The IntFOLD Server Results
Please cite the following papers:McGuffin, L.J., Atkins, J., Salehe, B.R., Shuid, A.N. & Roche, D.B. (2015) IntFOLD: an integrated server for modelling protein structures and functions from amino acid sequences. Nucleic Acids Research, 43, W169-73. PubMed
Roche, D. B., Buenavista, M. T., Tetchner, S. J. & McGuffin, L. J. (2011) The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction. Nucleic Acids Res., 39, W171-6. PubMed
Links to graphical output:
- Top 5 3D models
- Disorder prediction
- Domain boundary prediction
- Binding site prediction
- Full model quality assessment results
Download machine readable results in CASP format:
- TS (Tertiary Structure Prediction)
- DR (Disorder Prediction)
- DP (Domain Prediction)
- FN (Binding Site Prediction)
- QA (Model Quality Prediction)
Results will be available for 21 days after job completion (subject to server capacity)
| Top 5 3D models for T0547 | Help | ||||
| Model name (PDBsum links for templates used) | Confidence and P-value | Global model quality score | Local model quality plot (click images to download plots) | Model coloured by local quality (click images to view models, local errors and target coverage interactively) |
| nFOLD4_1twiA _COMA_TS1 |
HIGH: 2.851E-3 |
0.3435 |
 |
 |
| nFOLD4_1twiA _HHsearch_TS1 |
HIGH: 2.881E-3 |
0.3428 |
 |
 |
| nFOLD4_multi _HHsearch_TS1 1twiA 2p3eA |
HIGH: 3.141E-3 |
0.3367 |
 |
 |
| nFOLD4_2p3eA _HHsearch_TS2 |
HIGH: 3.25E-3 |
0.3343 |
 |
 |
| nFOLD4_2p3eA _COMA_TS2 |
HIGH: 3.345E-3 |
0.3322 |
 |
 |
McGuffin, L. J. (2008) Intrinsic disorder prediction from the analysis of multiple protein fold recognition models. Bioinformatics, 24, 1789-1804. PubMed
| Disorder prediction for T0547 | Help | |||
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| Click image to download plot in PostScript format. |
| Domain boundary prediction for T0547 | Help | |||
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| Click image to download model or view prediction using Jmol. The model above is coloured according to the predicted domains. |
Roche, D. B., Tetchner, S. J. & McGuffin, L. J. (2011) FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins. BMC Bioinformatics, 12, 160. PubMed
| Ligand binding residues prediction for T0547 | Help | |||
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| Click image to download model or view prediction using Jmol. Predicted ligand binding residues are shown as blue sticks in the image above. |
McGuffin, L. J. & Roche, D. B. (2010) Rapid model quality assessment for protein structure predictions using the comparison of multiple models without structural alignments. Bioinformatics, 26, 182-188. PubMed
| Full model quality assessment results for T0547 | Help | ||||
| Model name (PDBsum links for templates used) | Confidence and P-value | Global model quality score | Local model quality plot (click images to download plots) | Model coloured by local quality (click images to view models, local errors and target coverage interactively) |
| nFOLD4_1twiA _COMA_TS1 |
HIGH: 2.851E-3 |
0.3435 |
|
|
| nFOLD4_1twiA _HHsearch_TS1 |
HIGH: 2.881E-3 |
0.3428 |
|
|
| nFOLD4_multi _HHsearch_TS1 1twiA 2p3eA |
HIGH: 3.141E-3 |
0.3367 |
|
|
| nFOLD4_2p3eA _HHsearch_TS2 |
HIGH: 3.25E-3 |
0.3343 |
|
|
| nFOLD4_2p3eA _COMA_TS2 |
HIGH: 3.345E-3 |
0.3322 |
|
|
| nFOLD4_2qghA _HHsearch_TS7 |
HIGH: 3.435E-3 |
0.3304 |
 |
 |
| nFOLD4_2o0tA _HHsearch_TS3 |
HIGH: 3.598E-3 |
0.3272 |
 |
 |
| nFOLD4_1tufa _spk2_TS1 |
HIGH: 3.662E-3 |
0.3260 |
 |
 |
| nFOLD4_1f3tA _HHsearch_TS6 |
HIGH: 3.803E-3 |
0.3234 |
 |
 |
| nFOLD4_7odcA _HHsearch_TS8 |
HIGH: 3.834E-3 |
0.3228 |
 |
 |
| nFOLD4_1hkva _spk2_TS2 |
HIGH: 3.966E-3 |
0.3206 |
 |
 |
| nFOLD4_1hkva _sp3_TS2 |
HIGH: 4.212E-3 |
0.3165 |
 |
 |
| nFOLD4_1tufa _sp3_TS1 |
HIGH: 4.342E-3 |
0.3144 |
 |
 |
| nFOLD4_2j66a _spk2_TS5 |
HIGH: 4.405E-3 |
0.3135 |
 |
 |
| nFOLD4_2oo0A _HHsearch_TS9 |
HIGH: 4.421E-3 |
0.3133 |
 |
 |
| nFOLD4_2j66a _sp3_TS5 |
HIGH: 4.518E-3 |
0.3118 |
 |
 |
| nFOLD4_2plja _spk2_TS6 |
HIGH: 4.877E-3 |
0.3067 |
 |
 |
| nFOLD4_2nvaA _COMA_TS3 |
HIGH: 4.896E-3 |
0.3065 |
 |
 |
| nFOLD4_2pljA _HHsearch_TS10 |
HIGH: 4.903E-3 |
0.3064 |
 |
 |
| nFOLD4_7odca _spk2_TS4 |
HIGH: 5.021E-3 |
0.3048 |
 |
 |
| nFOLD4_1knwa _spk2_TS3 |
HIGH: 5.079E-3 |
0.3041 |
 |
 |
| nFOLD4_2yxxA _COMA_TS8 |
HIGH: 5.149E-3 |
0.3032 |
 |
 |
| nFOLD4_7odca _sp3_TS4 |
HIGH: 5.157E-3 |
0.3031 |
 |
 |
| nFOLD4_2yxxa _spk2_TS8 |
HIGH: 5.285E-3 |
0.3015 |
 |
 |
| nFOLD4_1knwa _sp3_TS3 |
HIGH: 5.318E-3 |
0.3011 |
 |
 |
| nFOLD4_2plja _sp3_TS7 |
HIGH: 5.388E-3 |
0.3002 |
 |
 |
| nFOLD4_2todA _COMA_TS6 |
HIGH: 5.481E-3 |
0.2991 |
 |
 |
| nFOLD4_7odcA _COMA_TS7 |
HIGH: 5.541E-3 |
0.2984 |
 |
 |
| nFOLD4_3btnA _COMA_TS5 |
HIGH: 5.575E-3 |
0.2980 |
 |
 |
| nFOLD4_2j66A _COMA_TS9 |
HIGH: 5.734E-3 |
0.2963 |
 |
 |
| nFOLD4_2j66A _HHsearch_TS4 |
HIGH: 5.815E-3 |
0.2954 |
 |
 |
| nFOLD4_2pljA _COMA_TS10 |
HIGH: 6.114E-3 |
0.2922 |
 |
 |
| nFOLD4_3btnA _HHsearch_TS5 |
HIGH: 6.724E-3 |
0.2862 |
 |
 |
| nFOLD4_2yxxa _sp3_TS8 |
HIGH: 8.532E-3 |
0.2715 |
 |
 |
| nFOLD4_7odca 2_sp3_TS6 |
MEDIUM: 2.217E-2 |
0.2176 |
 |
 |
| nFOLD4_7odca 2_spk2_TS7 |
MEDIUM: 2.232E-2 |
0.2173 |
 |
 |
| nFOLD4_3gwqa _spk2_TS9 |
MEDIUM: 3.441E-2 |
0.1953 |
 |
 |
| nFOLD4_3gwqa _sp3_TS9 |
MEDIUM: 4.812E-2 |
0.1790 |
 |
 |
| nFOLD4_1kqfa 2_sp3_TS10 |
POOR: 8.276E-1 |
0.0520 |
 |
 |
| nFOLD4_1wkba _spk2_TS10 |
POOR: 9.202E-1 |
0.0426 |
 |
 |