About the servers

This is the main page for the McGuffin bioinformatics group web servers. Several protein structure and function prediction methods are freely available for academic use. Please cite the relevant publications for each method. References for methods can be found on each server home page.

IntFOLD

An integrated server providing a single interface for the prediction of structure and function from sequence with interactive graphical output.

ModFOLD

Assess the quality of predicted 3D models.

ReFOLD

Fix the errors in 3D models of proteins.

PINOT

PINOT: Protein Interaction Network Online Tool.

FunFOLD

Predict protein-ligand interactions.

DISOclust

Predict the intrinsically disordered regions within a protein sequence.

DomFOLD

Predict the domain boundaries within a protein sequence.

nFOLD3

Our older unsupported method for building 3D models of a protein from sequence using fold recognition.

Downloads

Download standalone verisons of the methods.
Spokesmans shadow

News and Updates

  • May 2021: Biochem J. paper accepted - Publications
  • Apr 2021: ModFOLD8 and ReFOLD3 papers accepted by Nucleic Acids Research - Publications
  • Feb 2021: Two post docs are now working on our BBSRC project: BB/T018496/1 - Advancing capability in high performance protein structure and function prediction through optimisation of IntFOLD - People
  • Jan 2021: New hardware installed for IntFOLD component methods.
  • Dec 2020: Success at CASP14! Our ModFOLD8 server ranked among the top groups in QA. Panel talks were given in the QA and CASP-covid sessions and a poster was presented on our new ReFOLD3 method.
  • Sep 2020: New PhD students started - People
  • Aug 2020: Paper published in Blood - Publications
  • Jun 2020: Paper published in Cell Communication and Signaling - Publications
  • Jun 2020: Press release for CASP Commons research into SARS-CoV-2 protein structures.
  • May 2020: CASP14 prediction season begins! New servers and methods will be benchmarked.
  • Mar-Jun 2020: COVID-19 research - SARS-CoV-2 protein structures have been modelled using IntFOLD6 and scored with ModFOLD8 as part of CASP Commons 2020
  • Feb 2020: New hardware has been installed for the new versions of our methods - IntFOLD6 and ModFOLD8 will be benchmarked in CASP14 and CAMEO.
  • Oct 2019: New PhD students started - People
  • Sep 2019: Genome Biology CAFA3 paper published - Publications
  • Jul 2019: Estimates of Model Accuracy paper published for the CASP13 Proteins Special Issue - Publications
  • Jun 2019: PLOS ONE paper published - Publications
  • May 2019: Int. J Mol. Sci. paper accepted - Publications
  • Apr 2019: IntFOLD5 server paper accepted by Nucleic Acids Research - Publications
  • Dec 2018: Success at CASP13 (we are among the top few ranked groups in QA and TBM)! Invited talk & panel contribution given and two posters presented on our new methods and servers. Quoted in Guardian article re: CASP13 and DeepMind
  • Oct 2018: New PhD student started - People
  • Sep 2018: CASP13 prediction season complete. 5 abstracts prepared for Dec conference describing IntFOLD5, ModFOLD7, ReFOLD2, MultiFOLD and ModFOLDdock. New servers and downloads coming soon...
  • Jul 2018: Nature Sci. Rep. paper published - Publications
  • May 2018: CASP13 prediction season begins! New servers and methods will be benchmarked.
  • Feb 2018: Dr Bajuna Salehe to rejoin School as a Bioinformatician for Genomics
  • Dec 2017: Int. J Mol. Sci. paper accepted - Publications
  • Nov 2017: New Lecturer in Bioinformatics for Genomics, Dr Soon Gweon, has joined the School
  • Oct 2017: Estimates of Model Accuracy paper accepted for the CASP12 Proteins Special Issue - Publications
  • Jul 2017: Template Based Modelling paper accepted for the CASP12 Proteins Special Issue - Publications
  • Apr 2017: ModFOLD6 server paper accepted by Nucleic Acids Research - Publications
  • Apr 2017: ReFOLD server paper accepted by Nucleic Acids Research - Publications
  • Apr 2017: PLOS ONE paper accepted - Publications
  • Dec 2016: Success at CASP12 (we are among the top few ranked in TBM and QA)! Two talks and three posters presented on our new methods and servers. The ReFOLD and ModFOLD6 servers are now online.
  • Nov 2016: Two new PhD students to start - People
  • Sep 2016: CASP12 prediction season complete. 5 abstracts submitted for Dec conference describing IntFOLD4, ModFOLD6, ReFOLD, MultiFOLD and ModFOLDIA. New servers and downloads coming soon...
  • May-Aug 2016: CASP12 prediction season! New servers and methods will be benchmarked.
  • Apr 2016: Methods in Mol. Biol. paper published - Publications
  • Feb 2016: Won the University Best Research Output prize in the Health Theme for paper in J. Clin. Invest. Pubmed
  • Feb 2016: Nature Sci. Rep. paper published - Publications
  • Jan 2016: Methods in Mol. Biol. paper published - Publications
  • Dec 2015: Int. J. Mol. Sci. paper accepted - Publications
  • Oct 2015: New PhD student started - People
  • Aug 2015: Int. J. Mol. Sci. paper accepted - Publications
  • May 2015: J. Nutr. Biochem. paper accepted - Publications
  • Apr 2015: New PhD student started - People
  • Mar 2015: New IntFOLD server paper accepted by Nucleic Acids Research - Publications
  • Feb 2015: Science paper published containing results from the IntFOLD server - Press release

Page navigation

 

Search Form