Claire Williams

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+44 (0) 118 378 7540
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Professor
- Director of Research
- Module Convenor, PY3PCD
- Module Convenor, PY3NUT.
Areas of interest
Cannabinoids and behaviour, nutrition and cognition, epilepsy, reward, appetite, flavonoids.Teaching
- Undergraduate: neuroscience
- Postgraduate: neuroscience.
Research centres and groups
Nutrition and Health
Academic qualifications
- BSc, Nottingham Trent
- PhD, Reading.
Publications
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Ma, X.
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Li, Y.
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Xu, Y.
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Gibson, R.
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Williams, C.
ORCID: 0000-0003-4452-671X , Lawrence, A. , Nosarti, C. , Dazzan, P. , Rodriguez Mateos, A. (2023) Plant-based dietary patterns and their association with mood in healthy individuals. Food & Function , 14 (5). pp. 2326-2337. ISSN: 2042-650X | doi: https://dx.doi.org/10.1039/D2FO02951K
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Field, D.
ORCID: 0000-0003-4041-8404 , Cracknell, R. , Eastwood, J. , Scarfe, P.
ORCID: 0000-0002-3587-6198 , Williams, C.
ORCID: 0000-0003-4452-671X , Zheng, Y. , Tavassoli, T. (2022) High‐dose vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression. Human Psychopharmacology: Clinical and Experimental , 37 (6). pp 0. ISSN: 1099-1077 | doi: https://dx.doi.org/10.1002/hup.2852
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Cheng, N.
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Bell, L.
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Lamport, D.
ORCID: 0000-0002-4592-0439 , Williams, C.
ORCID: 0000-0003-4452-671X (2022) Dietary flavonoids and human cognition: a meta‐analysis. Molecular Nutrition & Food Research , 66 (21). pp 0. ISSN: 1613-4125 | doi: https://dx.doi.org/10.1002/mnfr.202100976
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Lamport, D.
ORCID: 0000-0002-4592-0439 , Wu, S. , Drever-Heaps, J. , Hugueniot, O. , Jones, D. , Kennedy, O. , Williams, C.
ORCID: 0000-0003-4452-671X , Butler, L. (2021) Can public health interventions change immediate and long-term dietary behaviours? Encouraging evidence from a pilot study of the U.K. Change4Life Sugar Swaps campaign. Nutrients , 14 (1). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu14010068
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Bell, L.
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Whyte, A.
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Duysburgh, C.
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Marzorati, M.
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Van den Abbeele, P.
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Le Cozannet, R.
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Fança-Berthon, P.
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Fromentin, E.
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Williams, C.
ORCID: 0000-0003-4452-671X (2021) A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost®) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action. European Journal of Nutrition ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-021-02654-5
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Vauzour, D.
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Rendeiro, C.
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D'Amato, A.
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Waffo-Teguo, P.
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Richard, T.
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Merillon, J.
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Pontifex, M.
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Connell, E.
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Muller, M.
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Butler, L.
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Williams, C.
ORCID: 0000-0003-4452-671X , Spencer, J. (2021) Anthocyanins promote learning through modulation of synaptic plasticity related proteins in an animal model of ageing. Antioxidants , 10 (8). ISSN: 2076-3921 | doi: https://dx.doi.org/10.3390/antiox10081235
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Eastwood, J.
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Walton, G.
ORCID: 0000-0001-5426-5635 , Van Hemert, S. , Williams, C.
ORCID: 0000-0003-4452-671X , Lamport, D.
ORCID: 0000-0002-4592-0439 (2021) The effect of probiotics on cognitive function across the human lifespan: a systematic review. Neuroscience and Biobehavioral Reviews , 128 pp. 311-327. ISSN: 0149-7634 | doi: https://dx.doi.org/10.1016/j.neubiorev.2021.06.032
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Barfoot, K.
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Istas, G.
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Feliciano, R.
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Lamport, D.
ORCID: 0000-0002-4592-0439 , Riddell, P. , Rodriguez-Mateos, A. , Williams, C.
ORCID: 0000-0003-4452-671X (2021) Effects of daily consumption of wild blueberry on cognition and urinary metabolites in school‑aged children: a pilot study. European Journal of Nutrition ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-021-02588-y
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Lamport, D.
ORCID: 0000-0002-4592-0439 and Williams, C.
ORCID: 0000-0003-4452-671X (2021) Polyphenols and cognition in humans: an overview of current evidence from recent systematic reviews and meta-analyses. Brain Plasticity , 6 (2). pp. 139-153. ISSN: 2213-6312 | doi: https://dx.doi.org/10.3233/bpl-200111
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Bell, L.
and
Williams, C.
ORCID: 0000-0003-4452-671X (2021) Blueberry benefits to cognitive function across the lifespan. International Journal of Food Sciences and Nutrition , 72 (5). pp. 650-652. ISSN: 1465-3478 | doi: https://dx.doi.org/10.1080/09637486.2020.1852192
- Whyte, A. , Rahman, S. , Bell, L. , Edirisinghe, I. , Krikorian, R. , Williams, C. , Burton-Freeman, B. (2021) Improved metabolic function and cognitive performance in middle-aged adults following a single dose of wild blueberry. European Journal of Nutrition , 60 (3). pp. 1521-1536. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-020-02336-8
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Williams, C.
ORCID: 0000-0003-4452-671X and Stephens, G.
ORCID: 0000-0002-8966-4238 (2020) Development of cannabidiol as a treatment for severe childhood epilepsies. British Journal of Pharmacology , 177 (24). pp. 5509-5517. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1111/bph.15274
- Whyte, A. , Lamport, D. , Schafer, G. , Williams, C. (2020) The cognitive effects of an acute wild blueberry intervention on 7- to 10-year-olds using extended memory and executive function task batteries. Food & Function , 11 (5). pp. 4793-4801. ISSN: 2042-650X | doi: https://dx.doi.org/10.1039/C9FO02284H
- Fisk, J. , Khalid, S. , Reynolds, S. , Williams, C. (2020) Effect of 4 weeks daily wild blueberry supplementation on symptoms of depression in adolescents. British Journal of Nutrition , 124 (2). pp. 181-188. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114520000926
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Bell, L.
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Whyte, A.
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Lamport, D.
ORCID: 0000-0002-4592-0439 , Spencer, J. , Butler, L. , Williams, C.
ORCID: 0000-0003-4452-671X (2020) Grape seed polyphenol extract and cognitive function in healthy young adults: A randomised, placebo-controlled, parallel-groups acute-on-chronic trial. Nutritional Neuroscience , 25 (1). pp. 54-63. ISSN: 1028-415X | doi: https://dx.doi.org/10.1080/1028415X.2019.1708033
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Patra, P.
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Serafeimidou-Pouliou, E.
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Bazelot, M.
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Whalley, B.
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Williams, C.
ORCID: 0000-0003-4452-671X , McNeish, A. (2020) Cannabidiol (CBD) improves survival and behavioural comorbidities of Dravet syndrome in mice. British Journal of Pharmacology , 177 (12). pp. 2779-2792. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1111/bph.15003
- Perry, C. , Finch, P. , Muller-Taubenberger, A. , Leung, K. , Warren, E. , Damstra-Oddy, J. , Sharma, D. , Patra, P. , Glyn, S. , Boberska, J. , Stewart, B. , Baldwin, A. , Piscitelli, F. , Harvey, R. , Harwood, A. , Thompson, C. , Claus, S. , Greene, N. , McNeish, A. , Williams, C. , Whalley, B. , Williams, R. (2020) A new mechanism for Cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models. British Journal of Pharmacology , 177 (4). pp. 912-928. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1111/bph.14892
- Whyte, A. , Cheng, N. , Butler, L. , Lamport, D. , Williams, C. (2019) Flavonoid-rich mixed berries maintain and improve cognitive function over a 6 h period in young healthy adults. Nutrients , 11 (11). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu11112685
- Dodd, G. , Williams, C. , Butler, L. , Spencer, J. (2019) Acute effects of flavonoid-rich blueberry on cognitive and vascular function in healthy older adults. Nutrition and Healthy Aging , 5 (2). pp. 119-132. ISSN: 2451-9502 | doi: https://dx.doi.org/10.3233/nha-180056
- Hein, S. , Whyte, A. , Wood, E. , Rodriguez-Mateos, A. , Williams, C. (2019) Systematic review of the effects of blueberry on cognitive performance as we age. Journal of Gerontology: Series A , 74 (7). pp. 984-995. ISSN: 1079-5006 | doi: https://dx.doi.org/10.1093/gerona/glz082
- Brierley, D. , Harman, J. , Giallourou, N. , Leishman, E. , Roashan, A. , Mellows, B. , Bradshaw, H. , Swann, J. , Patel, K. , Whalley, B. , Williams, C. (2019) Chemotherapy-induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol. Journal of Cachexia, Sarcopenia and Muscle , 10 (4). pp. 844-859. ISSN: 2190-6009 | doi: https://dx.doi.org/10.1002/jcsm.12426
- Serra, I. , Scheldeman, C. , Bazelot, M. , Whalley, B. , Dallas, M. , De Witte, P. , Williams, C. (2019) Cannabidiol modulates phosphorylated rpS6 signalling in a zebrafish model of tuberous sclerosis complex. Behavioural Brain Research , 363 pp. 135-144. ISSN: 0166-4328 | doi: https://dx.doi.org/10.1016/j.bbr.2019.01.040
- Kang, S. , Hayashi, Y. , Bruyns-Haylett, M. , Baker, D. , Boura, M. , Wang, H. , Karatzas, K. , Serra, I. , Bithell, A. , Williams, C. , Field, D. , Zheng, Y. (2019) Supplemental vitamin B-12 enhances the neural response to sensory stimulation in the barrel cortex of healthy rats but does not affect spontaneous neural activity. Journal of Nutrition , 149 (5). pp. 730-737. ISSN: 1541-6100 | doi: https://dx.doi.org/10.1093/jn/nxz011
- Bell, L. and Williams, C. (2019) A pilot dose-response study of the acute effects of haskap berry extract (Lonicera caerulea L.) on cognition, mood and blood pressure in older adults. European Journal of Nutrition , 58 pp. 3325-3334. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-018-1877-9
- Patra, P. , Barker-Haliski, M. , White, H. , Whalley, B. , Glyn, S. , Sandhu, H. , Jones, N. , Bazelot, M. , Williams, C. , McNeish, A. (2019) Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models. Epilepsia , 60 (2). ISSN: 0013-9580 | doi: https://dx.doi.org/10.1111/epi.14629
- Barfoot, K. , May, G. , Lamport, D. , Ricketts, J. , Riddell, P. , Williams, C. (2019) The effects of acute wild blueberry supplementation on the cognition of 7-10 year old schoolchildren. European Journal of Nutrition , 58 (7). pp. 2911-2920. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-018-1843-6
- Whalley, B. , Lin, H. , Bell, L. , Hill, T. , Patel, A. , Gray, R. , Roberts, E. , Devinsky, O. , Bazelot, M. , Williams, C. , Stephens, G. (2019) Species-specific susceptibility to cannabis-induced convulsions. British Journal of Pharmacology , 176 (10). pp. 1506-1523. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1111/bph.14165
- Whyte, A. , Cheng, N. , Fromentin, E. , Williams, C. (2018) A randomized, double-blinded, placebo-controlled study to compare the safety and efficacy of low dose enhanced wild blueberry powder and wild blueberry extract (ThinkBlue™) in maintenance of episodic and working memory in older adults. Nutrients , 10 (6). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu10060660
- Bell, L. , Lamport, D. , Field, D. , Butler, L. , Williams, C. (2018) Practice effects in nutrition intervention studies with repeated cognitive testing. Nutrition & Healthy Aging , 4 (4). pp. 309-322. ISSN: 2451-9480 | doi: https://dx.doi.org/10.3233/NHA-170038
- Whyte, A. , Schafer, G. , Williams, C. (2017) The effect of cognitive demand on performance of an executive function task following wild blueberry supplementation in 7 to 10 years old children. Food & Function , 8 (11). pp. 4129-4138. ISSN: 2042-650X | doi: https://dx.doi.org/10.1039/c7fo00832e
- Bell, L. , Lamport, D. , Butler, L. , Williams, C. (2017) A study of glycaemic effects following acute anthocyanin-rich blueberry supplementation in healthy young adults. Food & Function , 8 (9). pp. 3104-3110. ISSN: 2042-650X | doi: https://dx.doi.org/10.1039/c7fo00724h
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Khalid, S.
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Barfoot, K.
ORCID: 0000-0002-2866-6467 , May, G. , Lamport, D. , Reynolds, S. , Williams, C. (2017) Effects of acute blueberry flavonoids on mood in children and young adults. Nutrients , 9 (2). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu9020158
- Turner, S. , Williams, C. , Iversen, L. , Whalley, B. (2017) Molecular pharmacology of phytocannabinoids. In: Kinghorn, A. , Falk, H. , Gibbons, S. , Kobayashi, J. , (eds.) Phytocannabinoids. Progress in the Chemistry of Organic Natural Products , 103. Progress in the Chemistry of Organic Natural Products , 103 pp. 61-101. ISSN: 2191-7043 ISBN: 9783319455396 | doi: https://dx.doi.org/10.1007/978-3-319-45541-9_3
- Brierley, D. , Samuels, J. , Duncan, M. , Whalley, B. , Williams, C. (2017) A cannabigerol-rich Cannabis sativa extract, devoid of ∆9-tetrahydrocannabinol, elicits hyperphagia in rats. Behavioural Pharmacology , 28 (4). pp. 280-284. ISSN: 0955-8810 | doi: https://dx.doi.org/10.1097/FBP.0000000000000285
- Neshatdoust, S. , Saunders, C. , Castle, S. , Vauzour, D. , Williams, C. , Butler, L. , Lovegrove, J. , Spencer, J. (2016) High-flavonoid intake induces cognitive improvement linked to changes in serum brain-derived neurotrophic factor: two randomised,controlled trials. Nutrition and Healthy Ageing , 4 (1). pp. 81-93. ISSN: 2451-9502 | doi: https://dx.doi.org/10.3233/NHA-1615
- Lamport, D. , Pal, D. , Macready, A. , Barbosa Boucas, S. , Fletcher, J. , Williams, C. , Spencer, J. , Butler, L. (2016) The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow: an acute, randomised, placebo controlled crossover trial in healthy young adults. British Journal of Nutrition , 116 (12). pp. 2160-2168. ISSN: 1475-2662 | doi: https://dx.doi.org/10.1017/S000711451600430X
- Khalid, S. , Williams, C. , Reynolds, S. (2016) Is there an association between diet and depression in children and adolescents? A systematic review. British Journal of Nutrition , 116 (12). pp. 2097-2108. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114516004359
- Brierley, D. , Samuels, J. , Duncan, M. , Whalley, B. , Williams, C. (2016) Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats. Psychopharmacology , 233 (19-20). pp. 3603-3613. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-016-4397-4
- Modebadze, T. , Morgan, N. , Peres, I. , Hadid, R. , Amada, N. , Hill, C. , Williams, C. , Stanford, I. , Morris, C. , Jones, R. , Whalley, B. , Woodhall, G. (2016) A low mortality, high morbidity reduced intensity status epilepticus (RISE) model of epilepsy and epileptogenesis in the rat. PLoS ONE , 11 (2). ISSN: 1932-6203 | doi: https://dx.doi.org/10.1371/journal.pone.0147265
- Whyte, A. , Schafer, G. , Williams, C. (2016) Cognitive effects following acute wild blueberry supplementation in 7 – 10 year old children. European Journal of Nutrition , 55 (6). pp. 2151-2162. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-015-1029-4
- Brierley, D. , Samuels, J. , Duncan, M. , Whalley, B. , Williams, C. (2016) Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea. Psychopharmacology , 233 (2). pp. 243-254. ISSN: 1432-2072 | doi: https://dx.doi.org/10.1007/s00213-015-4100-1
- Bell, L. , Lamport, D. , Butler, L. , Williams, C. (2015) A review of the cognitive effects observed in humans following acute supplementation with flavonoids, and their associated mechanisms of action. Nutrients , 7 (12). pp. 10290-10306. ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu7125538
- Lamport, D. , Pal, D. , Moutsiana, C. , Field, D. , Williams, C. , Spencer, J. , Butler, L. (2015) The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial. Psychopharmacology , 232 (17). pp. 3327-3234. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-015-3972-4
- Kean, R. , Lamport, D. , Dodd, G. , Freeman, J. , Williams, C. , Ellis, J. , Butler, L. , Spencer, J. (2015) Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk randomised, double-blind, placebo-controlled trial in healthy older adults. American Journal of Clinical Nutrition , 101 (3). pp. 506-514. ISSN: 0002-9165 | doi: https://dx.doi.org/10.3945/ajcn.114.088518
- Whyte, A. and Williams, C. (2015) A pilot study investigating the effects of a single dose of a flavonoid-rich blueberry drink on memory in 8-10 year old children. Nutrition , 31 (3). pp. 531-534. ISSN: 0899-9007 | doi: https://dx.doi.org/10.1016/j.nut.2014.09.013
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Rendeiro, C.
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Foley, A.
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Lau, V.
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Ring, R.
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Rodriguez-Mateos, A.
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Vauzour, D.
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Williams, C.
ORCID: 0000-0003-4452-671X , Regan, C. , Spencer, J. (2014) A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats. Neuropharmacology , 79 pp. 335-344. ISSN: 0028-3908 | doi: https://dx.doi.org/10.1016/j.neuropharm.2013.12.003
- Hill, A. , Jones, N. , Smith, I. , Hill, C. , Williams, C. , Stephens, G. , Whalley, B. (2014) Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se. Neuroscience Letters , 566 pp. 269-274. ISSN: 0304-3940 | doi: https://dx.doi.org/10.1016/j.neulet.2014.03.013
- Amada, N. , Yamasaki, Y. , Williams, C. , Whalley, B. (2013) Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression. PeerJ ISSN: 2167-8359 | doi: https://dx.doi.org/10.7717/peerj.214
- Hill, T. , Cascio, M. , Romano, B. , Duncan, M. , Pertwee, R. , Williams, C. , Whalley, B. , Hill, A. (2013) Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB 1 receptor-independent mechanism. British Journal of Pharmacology , 170 (3). pp. 679-692. ISSN: 1476-5381 | doi: https://dx.doi.org/10.1111/bph.12321
- Corona, G. , Vauzour, D. , Hercelin, J. , Williams, C. , Spencer, J. (2013) Phenolic acid intake, delivered via moderate champagne wine consumption, improves spatial working memory via the modulation of hippocampal and cortical protein expression/activation.. Antioxidants & Redox Signaling , 19 (4). pp. 1676-1689. ISSN: 1523-0864 | doi: https://dx.doi.org/10.1089/ars.2012.5142
- Rendeiro, C. , Vauzour, D. , Rattray, M. , Waffo-Téguo, P. , Mérillon, J. , Butler, L. , Williams, C. , Spencer, J. (2013) Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor.. PLoS ONE , 8 (5). ISSN: 1932-6203 | doi: https://dx.doi.org/10.1371/journal.pone.0063535
- Hill, A. , Mercier, M. , Hill, T. , Glyn, S. , Jones, N. , Yamasaki, Y. , Futamura, T. , Duncan, M. , Stott, C. , Stephens, G. , Williams, C. , Whalley, B. (2012) Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models. British Journal of Pharmacology , 167 (8). pp. 1629-1642. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1111/j.1476-5381.2012.02207.x
- Rendeiro, C. , Vauzour, D. , Kean, R. , Butler, L. , Rattray, M. , Spencer, J. , Williams, C. (2012) Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology , 223 (3). pp. 319-330. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-012-2719-8
- Farrimond, J. , Whalley, B. , Williams, C. (2012) Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. Psychopharmacology , 223 (1). pp. 117-129. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-012-2697-x
- Jones, N. , Glyn, S. , Akiyama, S. , Hill, T. , Hill, A. , Weston, S. , Burnett, M. , Yamasaki, Y. , Stephens, G. , Whalley, B. , Williams, C. (2012) Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure , 21 (5). pp. 344-352. ISSN: 1059-1311 | doi: https://dx.doi.org/10.1016/j.seizure.2012.03.001
- Rendeiro, C. , Guerreiro, J. , Williams, C. , Spencer, J. (2012) Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. Proceedings of the Nutrition Society , 71 (2). pp. 246-262. ISSN: 1475-2719 | doi: https://dx.doi.org/10.1017/S0029665112000146
- Farrimond, J. , Whalley, B. , Williams, C. (2012) Non-D9-tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. Behavioural Pharmacology , 23 (1). pp. 113-117. ISSN: 0955-8810 | doi: https://dx.doi.org/10.1097/FBP.0b013e32834ed832
- Hill, A. , Williams, C. , Whalley, B. , Stephens, G. (2012) Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacology & Therapeutics , 133 (1). pp. 79-97. ISSN: 0163-7258 | doi: https://dx.doi.org/10.1016/j.pharmthera.2011.09.002
- Vauzour, D. , Corona, G. , Hercelin, J. , Garnotel, R. , Gillery, P. , Lovegrove, J. , Williams, C. , Spencer, J. (2011) Potential health effects of Champagne wine consumption. Journal of Wine Research , 22 (2). pp. 175-180. ISSN: 1469-9672 | doi: https://dx.doi.org/10.1080/09571264.2011.603251
- Farrimond, J. , Mercier, M. , Whalley, B. , Williams, C. (2011) Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. Phytotherapy Research , 25 (2). pp. 170-188. ISSN: 0951-418X | doi: https://dx.doi.org/10.1002/ptr.3375
- Field, D. , Williams, C. , Butler, L. (2011) Consumption of cocoa flavanols results in an acute improvement in visual and cognitive functions. Physiology & Behavior , 103 (3-4). pp. 255-260. ISSN: 0031-9384 | doi: https://dx.doi.org/10.1016/j.physbeh.2011.02.013
- Farrimond, J. , Whalley, B. , Williams, C. (2010) A low delta-9-tetrahydrocannabinol cannabis extract induces hyperphagia in rats . Behavioural Pharmacology , 21 (8). pp. 769-772. ISSN: 0955-8810 | doi: https://dx.doi.org/10.1097/FBP.0b013e328340a062
- Macready, A. , Butler, L. , Kennedy, O. , Ellis, J. , Williams, C. , Spencer, J. (2010) Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies. Nutrition Research Reviews , 23 (2). pp. 200-229. ISSN: 0954-4224 | doi: https://dx.doi.org/10.1017/S0954422410000119
- Farrimond, J. , Whalley, B. , Williams, C. (2010) Cannabis constituents modulate ∆9-tetrahydrocannabinol-induced hyperphagia in rats . Psychopharmacology , 210 (1). pp. 97-106. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-010-1821-z
- Hill, A. , Weston, S. , Jones, N. , Smith, I. , Bevan , S. , Williamson, E. , Stephens, G. , Williams, C. , Whalley, B. (2010) Δ9-tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rat. Epilepsia , 51 (8). pp. 1522-1532. ISSN: 0013-9580 | doi: https://dx.doi.org/10.1111/j.1528-1167.2010.02523.x
- Hanmer, L. , Riddell, P. , Williams, C. (2010) Using a runway paradigm to assess the relative strength of rats' motivations for enrichment objects. Behavior Research Methods , 42 (2). pp. 517-524. ISSN: 1554-351X | doi: https://dx.doi.org/10.3758/BRM.42.2.517
- Hill, A. , Jones, N. , Williams, C. , Stephens, G. , Whalley, B. (2010) Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. Journal of Neuroscience Methods , 185 (2). pp. 246 -256 . ISSN: 0165-0270 | doi: https://dx.doi.org/10.1016/j.jneumeth.2009.10.007
- Jones, N. , Hill, A. , Smith, I. , Bevan, S. , Williams, C. , Whalley, B. , Stephens, G. (2010) Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics , 332 (2). pp. 569-577. ISSN: 0022-3565 | doi: https://dx.doi.org/10.1124/jpet.109.159145
- Farrimond, . , Hill, . , Jones, . , Stephens, . , Whalley, . , Williams, . (2009) A cost-effective high-throughput digital system for observation and acquisition of animal behavioral data. Behavior Research Methods , 41 (2). pp. 446-451. ISSN: 1554-351X | doi: https://dx.doi.org/10.3758/BRM.41.2.446
- Hill, . , Jones, . , Williams, . , Stephens, . , Whalley, . (2009) Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. Journal of Neuroscience Methods , 185 (2). pp. 246-256. ISSN: 0165-0270 | doi: https://dx.doi.org/10.1016/j.jneumeth.2009.10.007.
- Williams, . , Hanmer, . , Riddell, . (2009) The effect of the functional attributes of objects within the caged environment on interaction time in laboratory rats. Applied Animal Behaviour Science , 120 (3-4). pp. 208-215. ISSN: 0168-1591 | doi: https://dx.doi.org/10.1016/j.applanim.2009.06.004
- Macready, A. , Kennedy, O. , Ellis, J. , Williams, C. , Spencer, J. , Butler, L. (2009) Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies. Genes and Nutrition , 4 (4). pp. 227-242. ISSN: 1555-8932 | doi: https://dx.doi.org/10.1007/s12263-009-0135-4
- Rendeiro, . , Spencer, . , Vauzour, . , Butler, . , Ellis, . , Williams, . (2009) The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes and Nutrition , 4 (4). pp. 251-270. ISSN: 1555-8932 | doi: https://dx.doi.org/10.1007/s12263-009-0137-2
- Farrimond, J. , Hill, A. , Jones, N. , Stephens, G. , Whalley, B. , Williams, C. (2009) A cost-effective high-throughput digital system for observation and acquisition of animal behavioral data. Behavior Research Methods , 41 (2). pp. 446-451. ISSN: 1554-351X | doi: https://dx.doi.org/10.3758/BRM.41.2.446
- Williams, C. , El Mohsen, M. , Vauzour, D. , Rendeiro, C. , Butler, L. , Ellis, J. , Whiteman, M. , Spencer, J. (2008) Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radical Biology and Medicine , 45 (3). pp. 295-305. ISSN: 1873-4596 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2008.04.008
- Williams, . , Riddell, . , Scott, . (2008) Comparison of preferences for object properties in the rat using paired- and free-choice paradigms. Applied Animal Behaviour Science , 112 (1-2). pp. 146-157. ISSN: 0168-1591 | doi: https://dx.doi.org/10.1016/j.applanim.2007.07.013
- Kirkham, . and Williams, . (2004) Endocannabinoid receptor antagonists: potential for obesity treatment. Treatments in Endocrinology , 3 (6). pp. 345-60. ISSN: 1175-6349
- Higgs, . , Williams, . , Kirkham, . (2003) Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after Delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. Psychopharmacology , 165 (4). pp. 370-377. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s00213-002-1263-3
- Williams, C. and Kirkham, T. (2002) Observational analysis of feeding induced by Δ9-THC and anandamide. Physiology & Behavior , 76 (2). pp. 241-250. ISSN: 0031-9384 | doi: https://dx.doi.org/10.1016/S0031-9384(02)00725-4
- Kirkham, T. , Williams, C. , Fezza, F. , Marzo, V. (2002) Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. British Journal of Pharmacology , 136 (4). pp. 550-557. ISSN: 0007-1188 | doi: https://dx.doi.org/10.1038/sj.bjp.0704767
- Kirkham, T. and Williams, C. (2001) Endogenous cannabinoids and appetite. Nutrition Research Reviews , 14 (1). pp. 65-86. ISSN: 0954-4224
- Kirkham, T. and Williams, C. (2001) Synergistic efects of opioid and cannabinoid antagonists on food intake. Psychopharmacology , 153 (2). pp. 267-270. ISSN: 0033-3158 | doi: https://dx.doi.org/10.1007/s002130000596