Gunter Kuhnle
-
+44 (0) 118 378 7723
-
Professor
- Module Convenor for "Nutritional Epidemiology and Dietary Assessment (FB2NED)"
- Undergraduate Research Project Coordinator
- Member of Senate
- Director of the Chemical Analysis Facility (CAF).
Office
2-14Building location
Harry NurstenAreas of interest
Nutritional epidemiology – Development of objective measures of dietary intake and exposure to food bioactives and other compounds, including early exposure (e.g. childhood). My interest is in particular the development of such methods suitable for application in large-scale cohort studies.
Polyphenol metabolism and health – Association between polyphenol metabolism and health in large scale studies.
Association between meat intake and cancer – Investigation of the association between red and processed meat intake and the risk of colorectal and other cancer, in particular the elucidation of underlying mechanisms. Development of novel food products to reduce the associated risks.
Research centres and groups
- Hugh Sinclair Unit of Human Nutrition.
Academic qualifications
- Diplom Biochemiker – University of Leipzig, Germany
- Doctor Rerum Naturalium – University of Leipzig, Germany
- Postgraduate Certificate in Academic Practice (PGCAP).
Professional bodies/affiliations
- Fellow of the Higher Education Academy (FHEA).
Publications
-
Ottaviani, J.
,
Schroeter, H.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
(2023)
Measuring the intake of dietary bioactives: pitfalls and how to avoid them.
Molecular Aspects of Medicine
, 89
ISSN:
0098-2997
|
doi:
https://dx.doi.org/10.1016/j.mam.2022.101139
-
Crowe-White, K.
ORCID: 0000-0003-2497-4582
,
Evans, L.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Milenkovic, D.
,
Stote, K.
,
Wallace, T.
,
Handu, D.
,
Senkus, K.
(2022)
Flavan-3-ols and cardiometabolic health: first ever dietary bioactive guideline.
Advances in Nutrition
, 13
(6).
pp.
2070-2083.
ISSN:
2161-8313
|
doi:
https://dx.doi.org/10.1093/advances/nmac105
-
Trinh, D.
,
Radlinskaite, M.
,
Cheeseman, J.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Osborn, H.
,
Meleady, P.
,
Spencer, D.
,
Monopoli, M.
(2022)
Biomolecular corona stability in association with plasma
cholesterol level.
Nanomaterials
, 12
(15).
ISSN:
2079-4991
|
doi:
https://dx.doi.org/10.3390/nano12152661
-
Visioli, F.
ORCID: 0000-0002-1756-1723
,
Marangoni, F.
,
Fogliano, V.
,
Del Rio, D.
,
Martinez, J.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Buttriss, J.
,
Da Costa Ribeiro, H.
,
Bier, D.
,
Poli, A.
(2022)
The ultra-processed foods hypothesis: a product processed well beyond the basic ingredients in the package.
Nutrition Research Reviews
ISSN:
0954-4224
|
doi:
https://dx.doi.org/10.1017/S0954422422000117
-
Wuni, R.
,
Nathania, E.
,
Ayyappa, A.
,
Lakshmipriya, N.
,
Ramya, K.
,
Gayathri, R.
,
Geetha, G.
,
Anjan, R.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Radha, V.
,
Mohan, V.
,
Sudha, V.
,
Vimaleswaran, K.
(2022)
Impact of lipid genetic risk score and saturated fatty acid intake on central obesity in an Asian Indian population.
Nutrients
, 14
(13).
ISSN:
2072-6643
|
doi:
https://dx.doi.org/10.3390/nu14132713
-
Albuloshi, T.
,
Dimala, C.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Bouhaimed, M.
,
Dodd, G.
,
Spencer, J.
(2022)
The effectiveness of vitamin D supplementation in reducing depressive symptoms: a systematic review and meta-analysis of Randomized Controlled Trials (RCTs).
Nutrition and Healthy Aging
, 6
(4).
pp.
301-318.
ISSN:
2451-9502
|
doi:
https://dx.doi.org/10.3233/nha-200094
-
Cheeseman, J.
,
Badia, C.
,
Thomson, R.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Gardner, R.
,
Spencer, D.
,
Osborn, H.
(2022)
Quantitative standards of 4-O acetyl and 9-O acetyl N-acetyl neuraminic acid for the analysis of plasma and serum.
ChemBioChem
, 23
(5).
ISSN:
1439-7633
|
doi:
https://dx.doi.org/10.1002/cbic.202100662
-
Wuni, R.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Azzari Wynn-Jones, A.
,
Vimaleswaran, K.
(2022)
A nutrigenetic update on CETP gene - diet interactions on lipid-related outcomes.
Current Atherosclerosis Reports
, 24
pp.
119-132.
ISSN:
1534-6242
|
doi:
https://dx.doi.org/10.1007/s11883-022-00987-y
-
Kuhnle, G.
ORCID: 0000-0002-8081-8931
(2021)
Essentially essential.
The American Journal of Clinical Nutrition
, 113
(5).
pp.
1073-1074.
ISSN:
0002-9165
|
doi:
https://dx.doi.org/10.1093/ajcn/nqaa450
-
De Souza, T.
,
Da Silveira, T.
,
Rodrigues, M.
,
Ruiz, A.
,
Neves, D.
,
Duarte, M.
,
Cunha-Santos, E.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Ribeiro, A.
,
Godoy, H.
(2021)
A study of the bioactive potential of seven neglected and underutilized leaves consumed in Brazil.
Food Chemistry
, 364
ISSN:
3088146
|
doi:
https://dx.doi.org/10.1016/j.foodchem.2021.130350
-
Younes, M.
,
Aggett, P.
,
Aguilar, F.
,
Crebelli, R.
,
Dusemund, B.
,
Filipič, M.
,
Frutos, M.
,
Galtier, P.
,
Gundert-Remy, U.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Lambré, C.
,
Leblanc, J.
,
Lillegaard, I.
,
Moldeus, P.
,
Mortensen, A.
,
Oskarsson, A.
,
Stankovic, I.
,
Waalkens-Berendsen, I.
,
Woutersen, R.
,
Wright, M.
,
Di Domenico, A.
,
Fairweather‐Tait, S.
,
McArdle, H.
,
Smeraldi, C.
,
Gott, D.
(2021)
Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources (Revision 1).
EFSA Journal
, 19
(3).
ISSN:
1831-4732
|
doi:
https://dx.doi.org/10.2903/j.efsa.2021.6552
-
van Breda, S.
ORCID: 0000-0003-1421-8214
,
Mathijs, K.
,
Pieters, H.
,
Sági‐Kiss, V.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Georgiadis, P.
,
Saccani, G.
,
Parolari, G.
,
Virgili, R.
,
Sinha, R.
,
Hemke, G.
,
Hung, Y.
,
Verbeke, W.
,
Masclee, A.
,
Vleugels‐Simon, C.
,
van Bodegraven, A.
,
de Kok, T.
(2021)
Replacement of nitrite in meat products by natural bioactive compounds results in reduced exposure to N‐Nitroso compounds: the PHYTOME project.
Molecular Nutrition & Food Research
, 65
(20).
pp.
2001214.
ISSN:
1613-4125
|
doi:
https://dx.doi.org/10.1002/mnfr.202001214
-
Fong, R.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Crozier, A.
ORCID: 0000-0001-7581-6782
,
Schroeter, H.
,
Ottaviani, J.
ORCID: 0000-0002-4909-0452
(2021)
Validation of a high-throughput method for the quantification of flavanol and procyanidin biomarkers and methylxanthines in plasma by UPLC-MS.
Food & Function
ISSN:
2042-650X
|
doi:
https://dx.doi.org/10.1039/D1FO01228B
-
Sinha, R.
,
Zhao, N.
ORCID: 0000-0002-7762-3949
,
Goedert, J.
,
Byrd, D.
ORCID: 0000-0003-4275-7901
,
Wan, Y.
,
Hua, X.
,
Hullings, A.
,
Knight, R.
,
Breda, S.
,
Mathijs, K.
,
de Kok, T.
ORCID: 0000-0003-2102-3626
,
Ward, M.
,
Pieters, H.
,
Sági-Kiss, V.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Georgiadis, P.
,
Saccani, G.
,
Parolari, G.
,
Virgili, R.
,
Hemke, G.
,
Hung, Y.
,
Verbeke, W.
,
Masclee, A.
,
Vleugels-Simon, C.
,
van Bodegraven, A.
,
Dobbelaere, D.
,
Vandewynkel, A.
,
van der Kruijk, R.
,
Egberts, F.
,
van Helvoirt, J.
(2021)
Effects of processed meat and drinking water nitrate on oral and fecal microbial populations in a controlled feeding study.
Environmental Research
, 197
ISSN:
0013-9351
|
doi:
https://dx.doi.org/10.1016/j.envres.2021.111084
-
Cheeseman, J.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Stafford, G.
,
Gardner, R.
,
Spencer, D.
,
Osborn, H.
(2021)
Sialic acid as a potential biomarker for cardiovascular disease, diabetes and cancer.
Biomarkers in Medicine
, 15
(11).
pp.
911-928.
ISSN:
1752-0363
|
doi:
https://dx.doi.org/10.2217/bmm-2020-0776
-
Perrar, I.
,
Buyken, A.
,
Penczynski, K.
,
Remer, T.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Herder, C.
,
Roden, M.
,
Della Corte, K.
,
Nöthlings, U.
,
Alexy, U.
ORCID: 0000-0002-1488-5175
(2021)
Relevance of fructose intake in adolescence for fatty liver indices in young adulthood.
European Journal of Nutrition
, 60
pp.
3029-3041.
ISSN:
1436-6207
|
doi:
https://dx.doi.org/10.1007/s00394-020-02463-2
-
Kuhnle, G.
ORCID: 0000-0002-8081-8931
(2021)
Take my breath away: measuring sugar intake in exhaled air.
The Journal of Nutrition
, 151
(3).
pp.
457-458.
ISSN:
1938-3207
|
doi:
https://dx.doi.org/10.1093/jn/nxaa390
-
Della Corte, K.
,
Penczynski, K.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Perrar, I.
,
Herder, C.
,
Roden, M.
,
Wudy, S.
,
Remer, T.
,
Alexy, U.
,
Buyken, A.
(2021)
The prospective association of dietary sugar intake in adolescence with risk markers of Type 2 Diabetes in young adulthood.
Frontiers in Nutrition
, 7
ISSN:
2296-861X
|
doi:
https://dx.doi.org/10.3389/fnut.2020.615684
-
Ramne, S.
ORCID: 0000-0003-1291-4494
,
Brunkwall, L.
,
Ericson, U.
ORCID: 0000-0003-4629-4318
,
Gray, N.
ORCID: 0000-0002-0094-5245
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Nilsson, P.
ORCID: 0000-0002-5652-8459
,
Orho-Melander, M.
ORCID: 0000-0002-3578-2503
,
Sonestedt, E.
ORCID: 0000-0002-0747-4562
(2021)
Gut microbiota composition in relation to intake of added sugar, sugar-sweetened beverages and artificially sweetened beverages in the Malmö Offspring Study.
European Journal of Nutrition
, 60
pp.
2087-2097.
ISSN:
1436-6207
|
doi:
https://dx.doi.org/10.1007/s00394-020-02392-0
-
Cheeseman, J.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Spencer, D.
,
Osborn, H.
(2021)
Assays for the identification and quantification of sialic acids: challenges, opportunities and future perspectives.
Bioorganic & Medicinal Chemistry
, 30
ISSN:
0968-0896
|
doi:
https://dx.doi.org/10.1016/j.bmc.2020.115882
-
Ottaviani, J.
,
Britten, A.
,
Lucarelli, D.
,
Luben, R.
,
Mulligan, A.
,
Lentjes, M.
,
Fong, R.
,
Gray, N.
,
Grace, P.
,
Mawson, D.
,
Tym, A.
,
Wierzbicki, A.
,
Forouhi, N.
,
Khaw, K.
,
Schroeter, H.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
(2020)
Biomarker‐estimated flavan‐3‐ol intake is associated with lower blood pressure in cross‐sectional analysis in EPIC Norfolk.
Scientific Reports
, 10
ISSN:
2045-2322
|
doi:
https://dx.doi.org/10.1038/s41598-020-74863-7
- Thøgersen, R. , Castro-Mejía, J. , Kræmer Sundekilde, U. , H. Hansen, L. , Gray, N. , Kuhnle, G. , Rye Jørgensen, N. , Kornerup Hansen, A. , Sandris Nielsen, D. , Bertram, H. (2020) Inulin and milk mineral fortification of a pork sausage exhibits distinct effects on the microbiome and biochemical activity in the gut of healthy rats. Food Chemistry , 331 ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2020.127291
- Flanagan, E. , Lamport, D. , Brennan, L. , Burnet, P. , Calabrese, V. , Cunnane, S. , de Wilde, M. , Dye, L. , Farrimond, J. , Emerson Lombardo, N. , Hartmann, T. , Hartung, T. , Kalliomäki, M. , Kuhnle, G. , La Fata, G. , Sala-Vila, A. , Samieri, C. , Smith, A. , Spencer, J. , Thuret, S. , Tuohy, K. , Turroni, S. , Vanden Berghe, W. , Verkuijl, M. , Verzijden, K. , Yannakoulia, M. , Geurts, L. , Vauzour, D. (2020) Nutrition and the ageing brain: moving towards clinical applications. Ageing Research Reviews , 62 pp 0. ISSN: 1568-1637 | doi: https://dx.doi.org/10.1016/j.arr.2020.101079
- Ramne, S. , Gray, N. , Hellstrand, S. , Brunkwall, L. , Enhörning, S. , Nilson, P. , Engström, G. , Orho-Melander, M. , Ericson, U. , Kuhnle, G. , Sonestedt, E. (2020) Comparing self-reported sugar intake with the sucrose and fructose biomarker from overnight urine samples in relation to cardiometabolic risk factors. Frontiers in Nutrition , 7 ISSN: 2296-861X | doi: https://dx.doi.org/10.3389/fnut.2020.00062
- da Silveira, T. , de Andrade Lima, M. , Meinhart, A. , Kuhnle, G. , Godoy, H. (2020) Effect of solvent composition on the extraction of phenolic compounds and antioxidant capacity of Bacaba juice (Oenocarpus bacaba Mart.). Food Analytical Methods , 13 (5). pp. 1119-1128. ISSN: 1936-976X | doi: https://dx.doi.org/10.1007/s12161-020-01726-2
- Perrar, I. , Gray, N. , Kuhnle, G. , Remer, T. , Buyken, A. , Alexy, U. (2020) Sugar intake among German adolescents: trends from 1990-2016 based on biomarker excretion in 24-h urine samples. British Journal of Nutrition , 124 (4). pp. 164-172. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114520000665
- da Silveira, T. , Cristianini, M. , Kuhnle, G. , Ribeiro, A. , Filho, J. , Godoy, H. (2019) Anthocyanins, non-anthocyanin phenolics, tocopherols and antioxidant capacity of açaí juice (Euterpe oleracea) as affected by high pressure processing and thermal pasteurization. Innovative Food Science & Emerging Technologies , 55 pp. 88-96. ISSN: 1466-8564 | doi: https://dx.doi.org/10.1016/j.ifset.2019.05.001
- van Breda, S. , Mathijs, K. , Sagi Kiss, V. , Kuhnle, G. , van der Veer, B. , Jones, R. , Sinha, R. , Ward, M. , de Kok, T. (2019) Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers. Environmental Health , 18 (1). ISSN: 1476-069X | doi: https://dx.doi.org/10.1186/s12940-019-0525-z
- Kuhnle, G. (2019) Stable isotope ratios - nutritional biomarkers of long-term intake?. American Journal of Clinical Nutrition , 110 (6). pp. 1265-1267. ISSN: 0002-9165 | doi: https://dx.doi.org/10.1093/ajcn/nqz239
- Ottaviani, J. , Fong, R. , Kimball, J. , Ensunsa, J. , Gray, N. , Vogiatzoglou, A. , Britten, A. , Lucarelli, D. , Luben, R. , Grace, P. , Mawson, D. , Tym, A. , Wierzbicki, A. , Smith, D. , Wareham, N. , Forouhi, N. , Khaw, K. , Schroeter, H. , Kuhnle, G. (2019) Evaluation of (−)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake. Scientific Reports , 9 ISSN: 2045-2322 | doi: https://dx.doi.org/10.1038/s41598-019-49702-z
- Younes, M. , Aquilina, G. , Castle, L. , Engel, K. , Fowler, P. , Frutos Fernandez, M. , Fürst, P. , Gürtler, R. , Husøy, T. , Mennes, W. , Moldeus, P. , Oskarsson, A. , Shah, R. , Waalkens‐Berendsen, I. , Wölfle, D. , Aggett, P. , Cupisti, A. , Fortes, C. , Kuhnle, G. , Lillegaard, I. , Scotter, M. , Giarola, A. , Rincon, A. , Tard, A. , Gundert‐Remy, U. (2019) Re‐evaluation of phosphoric acid–phosphates – di‐, tri‐ and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use. EFSA Journal , 17 (6). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2019.5674
- Thøgersen, R. , Gray, N. , Kuhnle, G. , Van Hecke, T. , De Smet, S. , Young, J. , Sundekilde, U. , Hansen, A. , Bertram, H. (2019) Inulin-fortification of a processed meat product attenuates formation of nitroso compounds in the gut of healthy rats. Food Chemistry , 302 ISSN: 3088146 | doi: https://dx.doi.org/10.1016/j.foodchem.2019.125339
- Berends, J. , van den Berg, L. , Guggeis, M. , Henckens, M. , Hossein, I. , de Joode, M. , Zamani, H. , van Pelt, K. , Beelen, N. , Kuhnle, G. , de Kok, T. , Van Breda, S. (2019) Consumption of nitrate-rich beetroot juice with or without vitamin C supplementation increases the excretion of urinary nitrate, nitrate, and N-nitroso compounds in humans. International Journal of Molecular Sciences , 20 (9). ISSN: 1422-0067 | doi: https://dx.doi.org/10.3390/ijms20092277
- Kristek, A. , Wiese, M. , Heuer, P. , Kosik, O. , Schar, M. , Soycan, G. , Alsharif, S. , Kuhnle, G. , Walton, G. , Spencer, J. (2019) Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota. British Journal of Nutrition , 121 (5). pp. 549-559. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114518003501
- Kuhnle, G. (2018) Stable isotope ratios: nutritional biomarker and more. Journal of Nutrition , 148 (12). pp. 1883-1885. ISSN: 1541-6100 | doi: https://dx.doi.org/10.1093/jn/nxy247
- Kristek, A. , Schar, M. , Soycan, G. , Alsharif, S. , Kuhnle, G. , Walton, G. , Spencer, J. (2018) The gut microbiota and cardiovascular health benefits: a focus on wholegrain oats. Nutrition Bulletin , 43 (4). pp. 358-373. ISSN: 1471-9827 | doi: https://dx.doi.org/10.1111/nbu.12354
- Sae-Lee, C. , Corsi, S. , Barrow, T. , Kuhnle, G. , Bollati, V. , Mathers, J. , Byun, H. (2018) Dietary intervention modifies DNA methylation age assessed by the epigenetic clock. Molecular Nutrition & Food Research , 62 (23). ISSN: 1613-4125 | doi: https://dx.doi.org/10.1002/mnfr.201800092
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Chrysafidis, D. , Gürtler, R. , Mosesso, P. , Parent‐Massin, D. , Tobback, P. , Rincon, A. , Tard, A. , Lambré, C. (2018) Re‐evaluation of propane‐1,2‐diol (E 1520) as a food additive. EFSA Journal , 16 (4). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5235
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Wright, M. , Di Domenico, A. , Van Loveren, H. , Giarola, A. , Horvath, Z. , Lodi, F. , Riolo, F. , Woutersen, R. (2018) Re‐evaluation of stannous chloride (E 512) as food additive. EFSA Journal , 16 (6). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5295
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Lindtner, O. , Tlustos, C. , Tard, A. , Leblanc, J. (2018) Refined exposure assessment of polyethylene glycol (E 1521) from its use as a food additive. EFSA Journal , 16 (6). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5293
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , McArdle, H. , Tobback, P. , Pizzo, F. , Rincon, A. , Smeraldi, C. , Gott, D. (2018) Evaluation of di‐calcium malate, used as a novel food ingredient and as a source of calcium in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes. EFSA Journal , 16 (6). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5291
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Filipic, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Brimer, L. , Mosesso, P. , Christodoulidou, A. , Cascio, C. , Tard, A. , Lodi, F. , Dusemund, B. (2018) Re‐evaluation of gellan gum (E 418) as food additive. EFSA Journal , 16 (6). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5296
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , McArdle, H. , Tobback, P. , Pizzo, F. , Rincon, A. , Smeraldi, C. , Gott, D. (2018) Evaluation of di‐magnesium malate, used as a novel food ingredient and as a source of magnesium in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes. EFSA Journal , 16 (6). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5292
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipicč, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Di Domenico, A. , Fairweather‐Tait, S. , McArdle, H. , Smeraldi, C. , Gott, D. (2018) Guidance on safety evaluation of sources of nutrients and bioavailability of nutrient from the sources. EFSA Journal , 16 (6). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5294
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Wright, M. , Lodi, F. , Rincon, A. , Smeraldi, C. , Woutersen, R. (2018) Evaluation of four new studies on the potential toxicity of titanium dioxide used as a food additive (E 171). EFSA Journal , 16 (7). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5366
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Briemer, L. , Pasquale, M. , Christodoulidou, A. , Horvath, Z. , Lodi, F. , Tard, A. , Dusemund, B. (2018) Re‐evaluation of glycerol esters of wood rosin (E 445) as a food additive. EFSA Journal , 16 (7). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5370
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Wright, M. , Di Domenico, A. , van Loveren, H. , Giarola, A. , Horvath, Z. , Lodi, F. , Tard, A. , Woutersen, R. (2018) Re‐evaluation of aluminium sulphates (E 520–523) and sodium aluminium phosphate (E 541) as food additives. EFSA Journal , 16 (7). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5372
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Brimer, L. , Mosesso, P. , Christodoulidou, A. , Horváth, Z. , Lodi, F. , Tard, A. , Dusemund, B. (2018) Re‐evaluation of propane‐1,2‐diol alginate (E 405) as a food additive. EFSA Journal , 16 (7). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5371
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Wright, M. , Di Domenico, A. , Van Loveren, H. , Giarola, A. , Horvath, Z. , Lodi, F. , Woutersen, R. (2018) Re‐evaluation of sodium ferrocyanide (E 535), potassium ferrocyanide (E 536) and calcium ferrocyanide (E 538) as food additives. EFSA Journal , 16 (7). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5374
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Lindtner, O. , Tlustos, C. , Tard, A. , Leblanc, J. (2018) Refined exposure assessment of extracts of rosemary (E 392) from its use as food additive. EFSA Journal , 16 (8). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5373
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Gürtler, R. , Mosesso, P. , Parent‐Massin, D. , Tobback, P. , Chrysafidis, D. , Rincon, A. , Tard, A. , Lambré, C. (2018) Re‐evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives. EFSA Journal , 16 (8). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5375
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Tobback, P. , Mcardle, H. , Germini, A. , Gott, D. (2018) Scientific opinion on the evaluation of authorised ferric sodium EDTA as an ingredient in the context of Regulation (EC) 258/97 on novel foods and Regulation (EU) 609/2013 on food intended for infants and young children, food for special medical purposes and total diet replacement for weight control. EFSA Journal , 16 (8). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5369
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Andrade, R. , Fortes, C. , Mosesso, P. , Restani, P. , Pizzo, F. , Smeraldi, C. , Wright, M. (2018) Scientific opinion on the safety of monacolins in red yeast rice. EFSA Journal , 16 (8). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5368
- Ottaviani, J. , Fong, R. , Kimball, J. , Ensunsa, J. , Britten, A. , Lucarelli, D. , Luben, R. , Grace, P. , Mawson, D. , Tym, A. , Wierzbicki, A. , Khaw, K. , Schroeter, H. , Kuhnle, G. (2018) Evaluation at scale of microbiome-derived metabolites as biomarker of flavan-3-ol intake in epidemiological studies. Scientific Reports , 8 (1). ISSN: 2045-2322 | doi: https://dx.doi.org/10.1038/s41598-018-28333-w
- Martin, O. , Naud, N. , Taché, S. , Debrauwer, L. , Chevolleau, S. , Dupuy, J. , Chantelauze, C. , Durand, D. , Pujos-Guillot, E. , Blas-Y-Estrada, F. , Urbano, C. , Kuhnle, G. , Santé-Lhoutellier, V. , Sayd, T. , Viala, D. , Blot, A. , Meunier, N. , Schlich, P. , Attaix, D. , Guéraud, F. , Scislowski, V. , Corpet, D. , Pierre, F. (2018) Targeting colon luminal lipid peroxidation limits colon carcinogenesis associated with red meat consumption. Cancer Prevention Research , 11 (9). ISSN: 1940-6207 | doi: https://dx.doi.org/10.1158/1940-6207.CAPR-17-0361
- Lu, F. , Kuhnle, G. , Cheng, Q. (2018) The effect of common spices and meat type on the formation of heterocyclic amines and polycyclic aromatic hydrocarbons in deep-fried meatballs. Food Control , 92 pp. 399-411. ISSN: 0956-7135 | doi: https://dx.doi.org/10.1016/j.foodcont.2018.05.018
- Okunade, O. , Niranjan, K. , Ghawi, S. , Kuhnle, G. , Methven, L. (2018) Supplementation of the diet by exogenous myrosinase via mustard seeds to increase the bioavailability of sulforaphane in healthy human subjects after the consumption of cooked broccoli. Molecular Nutrition & Food Research , 62 (18). ISSN: 1613-4125 | doi: https://dx.doi.org/10.1002/mnfr.201700980
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Chrysafidis, D. , Gürtler, R. , Mosesso, P. , Parent‐Massin, D. , Tobback, P. , Cascio, C. , Rincon, A. , Lambré, C. (2018) Re‐evaluation of sodium, potassium and calcium salts of fatty acids (E 470a) and magnesium salts of fatty acids (E 470b) as food additives. EFSA Journal , 16 (3). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5180
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Tobback, P. , Rincon, A. , Smeraldi, C. , Gott, D. (2018) Safety in use of glucosylated steviol glycosides as a food additive in different food categories. EFSA Journal , 16 (2). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5181
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Andrade, R. , Fortes, C. , Mosesso, P. , Restani, P. , Pizzo, F. , Smeraldi, C. , Papaioannou, A. , Wright, M. (2018) Safety of hydroxyanthracene derivatives for use in food. EFSA Journal , 16 (1). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5090
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Herman, L. , Tobback, P. , Pizzo, F. , Smeraldi, C. , Tard, A. , Papaioannou, A. , Gott, D. (2018) Safety of low‐substituted hydroxypropyl cellulose (L‐HPC) to be used as a food additive in food supplements in tablet form. EFSA Journal , 16 (1). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5062
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Chrysafidis, D. , Gürtler, R. , Mosesso, P. , Parent‐Massin, D. , Tobback, P. , Kovalkovicova, N. , Rincon, A. , Tard, A. , Lambré, C. (2018) Re‐evaluation of silicon dioxide (E 551) as a food additive. EFSA Journal , 16 (1). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5088
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Di Domenico, A. , Dusemund, B. , Filipič, M. , Jose Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Tobback, P. , Waalkens‐Berendsen, I. , Wright, M. , Tard, A. , Tasiopoulou, S. , Woutersen, R. (2018) Re‐evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives. EFSA Journal , 16 (1). ISSN: 1831–4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5047
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Lindtner, O. , Tlustos, C. , Tard, A. , Leblanc, J. (2018) Refined exposure assessment of sucrose esters of fatty acids (E 473) from its use as a food additive. EFSA Journal , 16 (1). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5087
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Tobback, P. , Smeraldi, C. , Gott, D. (2018) Safety of orthosilicic acid‐vanillin complex (OSA‐VC) as a novel food ingredient to be used in food supplements as a source of silicon and bioavailability of silicon from the source. EFSA Journal , 16 (1). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2018.5086
- Kuhnle, G. (2018) Nutrition epidemiology of flavan-3-ols: the known unknowns. Molecular Aspects of Medicine , 61 pp. 2-11. ISSN: 0098-2997 | doi: https://dx.doi.org/10.1016/j.mam.2017.10.003
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Brimer, L. , Lindtner, O. , Mosesso, P. , Christodoulidou, A. , Horváth, Z. , Lodi, F. , Dusemund, B. (2017) Re‐evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400–E 404) as food additives. EFSA Journal , 15 (11). ISSN: 18314732 | doi: https://dx.doi.org/10.2903/j.efsa.2017.5049
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Chrysafidis, D. , Gürtler, R. , Mosesso, P. , Tobback, P. , Rincon, A. , Horvath, Z. , Lambré, C. (2017) Re‐evaluation of mono‐ and di‐glycerides of fatty acids (E 471) as food additives. EFSA Journal , 15 (11). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2017.5045
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gott, D. , Gundert‐Remy, U. , Kuhnle, G. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Boon, P. , Chrysafidis, D. , Gürtler, R. , Mosesso, P. , Parent‐Massin, D. , Tobback, P. , Rincon, A. , Horvath, Z. , Lambré, C. (2017) Re‐evaluation of polyglycerol esters of fatty acids (E 475) as a food additive. EFSA Journal , 15 (12). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2017.5089
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Herman, L. , Tobback, P. , Pizzo, F. , Smeraldi, C. , Tard, A. , Papaioannou, A. , Gott, D. (2017) Extension of use of lycopene (E 160d) to certain meat preparations, meat products and fruit and vegetable preparations. EFSA Journal , 15 (12). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2017.5064
- Younes, M. , Aggett, P. , Aguilar, F. , Crebelli, R. , Dusemund, B. , Filipič, M. , Frutos, M. , Galtier, P. , Gundert‐Remy, U. , Kuhnle, G. , Lambré, C. , Leblanc, J. , Lillegaard, I. , Moldeus, P. , Mortensen, A. , Oskarsson, A. , Stankovic, I. , Waalkens‐Berendsen, I. , Woutersen, R. , Wright, M. , Herman, L. , Tobback, P. , Pizzo, F. , Smeraldi, C. , Tard, A. , Papaioannou, A. , Gott, D. (2017) Safety of nisin (E 234) as a food additive in the light of new toxicological data and the proposed extension of use. EFSA Journal , 15 (12). ISSN: 1831-4732 | doi: https://dx.doi.org/10.2903/j.efsa.2017.5063
- Campbell, R. , Tasevska, N. , Jackson, K. , Sagi Kiss, V. , di Paolo, N. , Mindell, J. , Lister, S. , Khaw, K. , Kuhnle, G. (2017) Association between urinary biomarkers of total sugars intake and measures of obesity in a cross-sectional study. PLoS ONE , 12 (7). ISSN: 1932-6203 | doi: https://dx.doi.org/10.1371/journal.pone.0179508
- Ferreira Ferreira da Silveira, T. , Lima de Souza, T. , Carvalho, A. , Ribeiro, A. , Kuhnle, G. , Godoy, H. (2017) White açaí juice (Euterpe oleracea): phenolic composition by LC-ESI-MS/MS, antioxidant capacity and inhibition effect on the formation of colorectal cancer related compounds. Journal of Functional Foods , 36 pp. 215-223. ISSN: 1756-4646 | doi: https://dx.doi.org/10.1016/j.jff.2017.07.001
- Kuhnle, G. , Luben, R. , Khaw, K. , Feelisch, M. (2017) Sulfate, nitrate and blood pressure − an EPIC interaction between sulfur and nitrogen. Pharmacological Research , 122 pp. 127-129. ISSN: 1043-6618 | doi: https://dx.doi.org/10.1016/j.phrs.2017.06.006
- Lu, F. , Kuhnle, G. , Cheng, Q. (2017) Vegetable oil as fat replacer inhibits formation of heterocyclic amines and 2 polycyclic aromatic hydrocarbons in reduced fat pork patties. Food Control , 81 pp. 113-125. ISSN: 0956-7135 | doi: https://dx.doi.org/10.1016/j.foodcont.2017.05.043
- Cortese-Krott, M. , Koning, A. , Kuhnle, G. , Nagy, P. , Bianco, C. , Pasch, A. , Wink, D. , Fukuto, J. , Jackson, A. , van Goor, H. , Olson, K. , Feelisch, M. (2017) The reactive species interactome: evolutionary emergence, biological significance, and opportunities for redox metabolomics and personalized medicine. Antioxidants & Redox Signaling , 27 (10). pp. 684-712. ISSN: 1523-0864 | doi: https://dx.doi.org/10.1089/ars.2017.7083
- Lu, F. , Kuhnle, G. , Cheng, Q. (2017) Heterocyclic amines and polycyclic aromatic hydrocarbons in commercial ready-to-eat meat products on UK market. Food Control , 73 (B). pp. 306-315. ISSN: 0956-7135 | doi: https://dx.doi.org/10.1016/j.foodcont.2016.08.021
- Kuhnle, G. and Hobbs, D. (2017) Red wine and pomegranate extracts suppress cured meat promotion of colonic mucin-depleted foci in carcinogen-induced rats. Nutrition and Cancer , 69 (2). pp. 289-298. ISSN: 1532-7914 | doi: https://dx.doi.org/10.1080/01635581.2017.1263745
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Velmurugan, S.
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Ming Gan, J.
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Rathod, K.
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Khambata, R.
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Ghosh, S.
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Hartley, A.
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van Eijl, S.
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Sagi Kiss, V.
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Chowdghury, T.
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Curtis, M.
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Kuhnle, G.
ORCID: 0000-0002-8081-8931
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Wade, W.
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Ahluwalia, A.
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Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.
American Journal of Clinical Nutrition
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pp.
25-38.
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0002-9165
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doi:
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Cortese-Krott, M.
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Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Dyson, A.
,
Fernandez, B.
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Grman, M.
,
Barrow, M.
,
McLeod, G.
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Ondrias, K.
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Nagy, P.
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Singer, M.
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Kelm, M.
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Butler, A.
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Feelisch, M.
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Nitrosopersulfide (SSNO-) targets soluble guanylyl cyclase and induces vasodilation in vivo.
BMC Pharmacology & Toxicology
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ISSN:
2050-6511
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doi:
https://dx.doi.org/10.1186/2050-6511-16-S1-A42
- Cortese-Krott, M. , Kuhnle, G. , Dyson, A. , Fernandez, B. , Grman, M. , DuMond, J. , Barrow, M. , McLeod, G. , Nakagawa, H. , Ondrias, K. , Nagy, P. , King, S. , Saavedra, J. , Keefer, L. , Singer, M. , Kelm, M. , Butler, A. , Feelisch, M. (2015) Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl. Proceedings of the National Academy of Sciences of the United States of America , 112 (34). pp. E4651-E4660. ISSN: 0027-8424 | doi: https://dx.doi.org/10.1073/pnas.1509277112
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- Heiss, C. , Sansone, R. , Karimi, H. , Krabbe, M. , Schuler, D. , Rodriguez Mateos, A. , Krämer, T. , Cortese-Krott, M. , Kuhnle, G. , Spencer, J. , Schroeter, H. , Merx, M. , Kelm, M. (2015) Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial. AGE , 37 (3). ISSN: 0161-9152 | doi: https://dx.doi.org/10.1007/s11357-015-9794-9
- Vogiatzoglou, A. , Mulligan, A. , Bhaniani, A. , Lentjes, M. , McTaggart, A. , Luben, R. , Heiss, C. , Kelm, M. , Merx, M. , Spencer, J. , Schroeter, H. , Khaw, K. , Kuhnle, G. (2015) Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Free Radical Biology and Medicine , 84 pp. 1-10. ISSN: 0891-5849 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2015.03.005
- Kuhnle, G. , Tasevska, N. , Lentjes, M. , Griffin, J. , Sims, M. , Richardson, L. , Aspinall, S. , Mulligan, A. , Luben, R. , Khaw, K. (2015) Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of EPIC-Norfolk. Public Health Nutrition , 18 (15). pp. 2815-2824. ISSN: 1368-9800 | doi: https://dx.doi.org/10.1017/S1368980015000300
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- Eid, N. , Walton, G. , Costabile, A. , Kuhnle, G. , Spencer, J. (2014) Polyphenols, glucosinolates, dietary fibre and colon cancer: Understanding the potential of specific types of fruit and vegetables to reduce bowel cancer progression. Nutrition and Aging , 2 (1). pp. 45-67. ISSN: 1879-7725 | doi: https://dx.doi.org/10.3233/NUA-130029
- Vanden Bussche, J. , Hemeryck, L. , Van Hecke, T. , Kuhnle, G. , Pasmans, F. , Moore, S. , Van de Wiele, T. , De Smet, S. , Vanhaecke, L. (2014) O6-carboxymethylguanine DNA adduct formation and lipid peroxidation upon in vitro gastrointestinal digestion of haem-rich meat. Molecular Nutrition & Food Research , 58 (9). pp. 1883-1896. ISSN: 1613-4125 | doi: https://dx.doi.org/10.1002/mnfr.201400078
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Patel, P.
,
Cooper, A.
,
O'Connell, T.
,
Kuhnle, G.
ORCID: 0000-0002-8081-8931
,
Kneale, C.
,
Mulligan, A.
,
Luben, R.
,
Brage, S.
,
Khaw, K.
,
Wareham, N.
,
Forouhi, N.
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Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study.
American Journal of Clinical Nutrition
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pp.
708-718.
ISSN:
0002-9165
|
doi:
https://dx.doi.org/10.3945/ajcn.113.068577
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- Vogiatzoglou, A. , Heuer, T. , Mulligan, A. , Lentjes, M. , Luben, R. , Kuhnle, G. (2013) Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II). European Journal of Nutrition , 53 (2). pp. 635-643. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-013-0572-0
- Chenni, F. , Tache, S. , Naud, N. , Hobbs, D. , Kuhnle, G. , Pierre, F. , Corpet, D. (2013) Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite. Nutrition and Cancer , 65 (2). pp. 227-233. ISSN: 1532-7914 | doi: https://dx.doi.org/10.1080/01635581.2013.749291
- Mulligan, A. , Kuhnle, G. , Lentjes, M. , van Scheltinga, V. , Powell, N. , McTaggart, A. , Bhaniani, A. , Khaw, K. (2013) Intakes and sources of isoflavones, lignans, enterolignans, coumestrol and soya-containing foods in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk), from 7-day food diaries, using a newly updated database. Public Health Nutrition , 16 (8). pp. 1454-1462. ISSN: 1368-9800 | doi: https://dx.doi.org/10.1017/S1368980012003904
- Kuhnle, G. , Joosen, A. , Kneale, C. , O'Connell, T. (2013) Carbon and nitrogen isotopic ratios of urine and faeces as novel nutritional biomarkers of meat and fish intake. European Journal of Nutrition , 52 (1). pp. 389-395. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-012-0328-2
- Cortese-Krott, M. , Rodriguez-Mateos, A. , Kuhnle, G. , Brown, G. , Feelisch, M. , Kelm, M. (2012) A multi-level analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins. Free Radical Biology and Medicine , 53 (11). pp. 2146-2158. ISSN: 0891-5849 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2012.09.008
- O'Connell, T. , Kneale, C. , Tasevska, N. , Kuhnle, G. (2012) The diet-body offset in human nitrogen isotopic values: a controlled dietary study. American Journal of Physical Anthropology , 149 (3). pp. 426-434. ISSN: 1096-8644 | doi: https://dx.doi.org/10.1002/ajpa.22140
- Cortese-Knott, M. , Rodriguez Mateos, A. , Sansone, R. , Kuhnle, G. , Thasian-Sivarajah, S. , Krenz, T. , Horn, P. , Krisp, C. , Wolters, D. , Heiß, C. , Kröncke, K. , Hogg, N. , Feelisch, M. , Kelm, M. (2012) Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease. Blood , 120 (20). pp. 4229-4237. ISSN: 0006-4971 | doi: https://dx.doi.org/10.1182/blood-2012-07-442277
- Gay, L. , Mitrou, P. , Keen, J. , Bowman, R. , Naguib, A. , Cooke, J. , Kuhnle, G. , Burns, P. , Luben, R. , Lentjes, M. , Khaw, K. , Ball, R. , Ibrahim, A. , Arends, M. (2012) Dietary, lifestyle and clinico-pathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk Study. Journal of Pathology , 228 (3). pp. 405-415. ISSN: 1096-9896 | doi: https://dx.doi.org/10.1002/path.4085
- Lahmann, P. , Hughes, M. , Ibiebele, T. , Mulligan, A. , Kuhnle, G. , Webb, P. (2012) Estimated intake of dietary phytoestrogens in Australian women and evaluation of correlates of phytoestrogen intake. Journal of Nutritional Science , 1 ISSN: 2048-6790 | doi: https://dx.doi.org/10.1017/jns.2012.11
- Zamora-Ros, R. , Knaze, V. , Lujan-Barrosso, L. , Kuhnle, G. , Mulligan, A. , Touillaud, M. , Slimani, N. , Romieu, I. , Powell, N. , Tumino, R. , Peeters, P. , de Magistris, S. , Ricceri, F. , Sonested, E. , Drake, I. , Hjartaker, A. , Skie, G. , Mouw, T. , Wark, P. , Domaguera, D. , Bueno-de-Mesquigta, H. , Ros, M. , Molina, E. , Sieri, S. , Quiros, J. , Huerta, J. , Tjonneland, A. , Halkjaer, J. , Masala, G. , Teucher, B. , Kaaks, R. , Travis, R. , Dilis, V. , Benetou, V. , Trichopoulou, A. , Amiano, P. , Ardanaz, E. , Boeing, H. , Forster, H. , Clavel-Chapelon, F. , Fagherazzi, G. , Perquier, F. , Johansson, G. , Johansson, I. , Cassidy, A. , Overvad, K. , Gonzales, C. (2012) Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort. European Journal of Clinical Nutrition , 66 (8). pp. 932-941. ISSN: 0954-3007 | doi: https://dx.doi.org/10.1038/ejcn.2012.36
- Kuhnle, G. (2012) Isoflavones. In: Nollet, L. and Toldra, F. , (eds.) Handbook of analysis of active compounds in functional foods. CRC Press , Boca Raton. pp. 405-434. ISBN: 9781439815885
- Kuhnle, G. (2012) Nutritional biomarkers for objective dietary assessment. Journal of the Science of Food and Agriculture , 92 (6). pp. 1145-1149. ISSN: 0022-5142 | doi: https://dx.doi.org/10.1002/jsfa.5631
- Ottaviani, J. , Momma, T. , Kuhnle, G. , Keen, C. , Schroeter, H. (2012) Structurally-related (−)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards. Free Radical Biology and Medicine , 52 (8). pp. 1403-1412. ISSN: 0891-5849 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2011.12.010
- Hebels, D. , Sveje, K. , de Kok, M. , van Herwijnen, M. , Kuhnle, G. , Engels, L. , Vieugels-Simon, C. , Mares, W. , Pierik, M. , Masclee, A. , Kleinjans, J. , de Kok, T. (2012) Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon. Food and Chemical Toxicology , 50 (2). pp. 95-103. ISSN: 0278-6915 | doi: https://dx.doi.org/10.1016/j.fct.2011.10.038
- Hebels, D. , Sveje, K. , de Kok, M. , van Herwijnen, M. , Kuhnle, G. , Engels, L. , Vieugels-Simon, C. , Mares, W. , Pierik, M. , Masclee, A. , Kleinjans, J. , de Kok, T. (2011) N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer. Cancer Letters , 77 (15). pp. 5220-5229. ISSN: 0304-3835 | doi: https://dx.doi.org/10.1016/j.canlet.2011.05.007
- Kuhnle, G. , Ward, H. , Vogiatzoglou, A. , Luben, R. , Mulligan, A. , Wareham, N. , Forouhi, N. , Khaw, K. (2011) Association between dietary phyto-oestrogens and bone density in men and postmenopausal women. British Journal of Nutrition , 106 (7). pp. 1063-1069. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114511001309
- Ward, H. , Kuhnle, G. , Mulligan, A. , Lentjes, M. , Luben, R. , Khaw, K. (2010) Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition–Norfolk in relation to phytoestrogen intake derived from an improved database. American Journal of Clinical Nutrition , 91 (2). pp. 440-448. ISSN: 0002-9165 | doi: https://dx.doi.org/10.3945/ajcn.2009.28282
- Kuhnle, G. and Bingham, S. (2010) Meat, protein and cancer. In: Milner, J. and Romagnolo, D. , (eds.) Bioactive Compounds and Cancer. Springer , Totowa. pp. 195-212. ISBN: 9781607616269
- Ward, H. and Kuhnle, G. (2010) Phytoestrogen consumption and association with breast, prostate and colorectal cancer in EPIC Norfolk. Archives of Biochemistry and Biophysics , 501 (1). pp. 170-175. ISSN: 0003-9861 | doi: https://dx.doi.org/10.1016/j.abb.2010.05.018
- Joosen, A. , Kuhnle, G. , Aspinall, S. , Barrow, T. , Lecommandeur, E. , Azqueta, A. , Collins, A. , Bingham, S. (2009) Effect of processed and red meat on endogenous nitrosation and DNA damage. Carcinogenesis , 30 (8). pp. 1402-1407. ISSN: 0143-3334 | doi: https://dx.doi.org/10.1093/carcin/bgp130
- Tzounis, . , Vulevic, . , Kuhnle, . , George, . , Leonczak, . , Gibson, . , Kwik-Uribe, . , Spencer, . (2008) Flavanol monomer-induced changes to the human faecal microflora. British Journal of Nutrition , 99 (4). pp. 782-792. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/s0007114507853384
- El Mohsen, . , Bayele, . , Kuhnle, . , Gibson, . , Debnam, . , Srai, . , Rice-Evans, . , Spencer, . (2006) Distribution of [H-3]trans-resveratrol in rat tissues following oral administration. British Journal of Nutrition , 96 (1). pp. 62-70. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1079/bjn20061810
- El Mohsen, M. , Marks, J. , Kuhnle, G. , Moore, K. , Debnam, E. , Srai, S. , Rice-Evans, C. , Spencer, J. (2006) Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. British Journal of Nutrition , 95 (1). pp. 51-58. ISSN: 1475-2662 | doi: https://dx.doi.org/10.1079/BJN20051596
- Lee, . , Munerol, . , Pollard, . , Youdim, . , Pannala, . , Kuhnle, . , Debnam, . , Rice-Evans, . , Spencer, . (2006) The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth. Free Radical Biology and Medicine , 40 (2). pp. 323-334. ISSN: 0891-5849 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2005.08.031
- Pollard, . , Kuhnle, . , Vauzour, . , Vafeiadou, . , Tzounis, . , Whiteman, . , Rice-Evans, . , Spencer, . (2006) The reaction of flavonoid metabolites with peroxynitrite. Biochemical and Biophysical Research Communications , 350 (4). pp. 960-968. ISSN: 0006-291X | doi: https://dx.doi.org/10.1016/j.bbrc.2006.09.131
- Spencer, J. , Kuhnle, G. , Hajirezaei, M. , Mock, H. , Sonnewald, U. , Rice-Evans, C. (2005) The genotypic variation of the antioxidant potential of different tomato varieties. Free Radical Research , 39 (9). pp. 1005-1016. ISSN: 1071-5762 | doi: https://dx.doi.org/10.1080/10715760400022293
- Abd El Mohsen, . , Marks, . , Kuhnle, . , Rice-Evans, . , Moore, . , Gibson, . , Debnam, . , Srai, . (2004) The differential tissue distribution of the citrus flavanone naringenin following gastric instillation. Free Radical Research , 38 (12). pp. 1329-1340. ISSN: 1071-5762 | doi: https://dx.doi.org/10.1080/10715760400017293
- Rechner, . , Smith, . , Kuhnle, . , Gibson, . , Debnam, . , Srai, . , Moore, . , Rice-Evans, . (2004) Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products. Free Radical Biology and Medicine , 36 (2). pp. 212-225. ISSN: 0891-5849 | doi: https://dx.doi.org/10.1016/j.freeradbiomed.2003.09.022
- Spencer, J. , Kuhnle, G. , Williams, R. , Rice-Evans, C. (2003) Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites. Biochemical Journal , 372 (1). pp. 173-181. ISSN: 0264-6021 | doi: https://dx.doi.org/10.1042/BJ20021972