- Senior Editor, Food Chemistry journal
- Co-Director of BBSRC Network Biomass Biorefinery Network
Dimitris Charalampopoulos

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+44 (0) 118 378 8216
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Professor
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Co-Chair of Departmental Staff Development and Wellbeing Committee
Office
2-17Building location
Harry NurstenAreas of interest
Dimitris’s research is in food biotechnology and aims to address key challenges for the transformation towards a more sustainable food system. Main drivers include the elimination of food loss and waste, the stimulation of the bioeconomy, the efficient utilisation of natural resources, and the development of more sustainable and healthier foods.
The main topics of focus are:
- Valorisation of food processing side-streams and wastes through industrial biotechnology and chemical/physical fractionation to produce functional components, e.g., polysaccharides, proteins.
- Bioprocess development for the microbial production of platform and speciality chemicals, e.g., lactic acid, exopolysaccharides, colourants.
- Microbial production, encapsulation, and delivery of probiotic microorganisms
- Enzymatic synthesis of prebiotic oligosaccharides with applications as functional food ingredients and gut bioactives
Postgraduate supervision
Research funding and postgraduate supervision
Dimitris has been awarded research funding from various agencies, including the UK Biotechnology and Biological Sciences Research Council (BBSRC), Global Challenges Research Fund (GCRF), Innovate UK, European Institute of Innovation & Technology (EIT) Food, as well as industry. He has supervised more than 20 PhD students to completion.
Academic qualifications
- BSc Chemistry, University of Crete, Greece
- MSc Food Biotechnology, University of Patras & University of Ulster
- PhD Fermentation, University of Manchester Institute of Science and Technology (UMIST)
Publications
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Zhang, G.
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Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 , Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Rodriguez Garcia, J.
ORCID: 0000-0002-4986-3144 (2023) Effect of defatted melon seed residue on dough development and bread quality. LWT-Food Science and Technology ISSN: 0023-6438 | doi: https://dx.doi.org/10.1016/j.lwt.2023.114892
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Yu, H.
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Bruzda, K.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2023) Impact of fermentation conditions and purification strategy on bacterial cellulose properties. Johnson Matthey Technology Review ISSN: 2056-5135 | doi: https://dx.doi.org/10.1595/205651323X16794186402492
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Li, Z.
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Zhan, G.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Guo, Z. (2023) Ionic liquid-mediated regeneration of cellulose dramatically improves decrystallization, TEMPO-mediated oxidation and alkyl/alkenyl succinylation. International Journal of Biological Macromolecules , 236 ISSN: 0141-8130 | doi: https://dx.doi.org/10.1016/j.ijbiomac.2023.123983
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Suttikul, S.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2023) Biotechnological production of optically pure 2,3-Butanediol by Bacillus subtilis based on Dissolved Oxygen Control Strategy. Fermentation , 9 (1). ISSN: 2311-5637 | doi: https://dx.doi.org/10.3390/fermentation9010015
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Kumar, V.
ORCID: 0000-0001-8967-6119 , Brancoli, P. , Narisetty, V. , Wallace, S. , Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Kumar Dubey, B. , Kumar, G. , Bhatnagar, A. , Kant Bhatia, S. , J.Taherzadeh, M. (2023) Bread waste – a potential feedstock for sustainable circular biorefineries. Bioresource Technology , 369 ISSN: 0960-8524 | doi: https://dx.doi.org/10.1016/j.biortech.2022.128449
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Azman, E.
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Yusof, N.
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Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 , Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 (2022) Stability enhancement of anthocyanins from blackcurrant (Ribes nigrum L.) pomace through intermolecular copigmentation. Molecules , 27 (17). ISSN: 1420-3049 | doi: https://dx.doi.org/10.3390/molecules27175489
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Luna, P.
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Risfaheri, ..
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Hoerudin, ..
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2022) Fractionation of carbohydrate polymers from Indonesian sorghum by-products. Food and Bioproducts Processing , 135 pp. 114-122. ISSN: 0960-3085 | doi: https://dx.doi.org/10.1016/j.fbp.2022.07.007
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Azman, E.
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Nor, N.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2022) Effect of acidified water on phenolic profile and antioxidant activity of dried blackcurrant (Ribes nigrum L.) pomace extracts. LWT-Food Science and Technology , 154 ISSN: 0023-6438 | doi: https://dx.doi.org/10.1016/j.lwt.2021.112733
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Eze, O.
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Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 , Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 (2022) Properties of protein isolates extracted by ultrasonication from soybean residue (okara). Food Chemistry , 368 ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2021.130837
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Baltulionis, G.
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Blight, M.
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Robin, A.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Watson, K. (2021) The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase. Journal of Structural Biology , 213 (3). ISSN: 1047-8477 | doi: https://dx.doi.org/10.1016/j.jsb.2021.107741
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Ta, L.
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Bujna, E.
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Kun, S.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Khutoryanskiy, V. (2021) Electrosprayed mucoadhesive alginate-chitosan microcapsules for gastrointestinal delivery of probiotics. International Journal of Pharmaceutics , 597 ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2021.120342
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de Andrade Lima, M.
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Andreou, R.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2021) Supercritical carbon dioxide extraction of phenolic compounds from potato (Solanum tuberosum) peels. Applied Sciences , 11 (8). ISSN: 2076-3417 | doi: https://dx.doi.org/10.3390/app11083410
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Cunningham, M.
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Vinderola, G.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Lebeer, S. , Sanders, M. , Grimaldi, R. (2021) Applying probiotics and prebiotics in new delivery formats – is the clinical evidence transferable?. Trends in Food Science & Technology ISSN: 0924-2244 | doi: https://dx.doi.org/10.1016/j.tifs.2021.04.009
- Azman, E. , House, A. , Charalampopoulos, D. , Chatzifragkou, A. (2021) Effect of dehydration on phenolic compounds and antioxidant activity of blackcurrant (Ribes nigrum L.) pomace. International Journal of Food Science and Technology , 56 (2). pp. 600-607. ISSN: 1365-2621 | doi: https://dx.doi.org/10.1111/ijfs.14762
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Picchioni, F.
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Warren, G.
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Lambert, S.
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Balcombe, K.
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Robinson, J.
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Srinivasan, C.
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Gomez, L.
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Laura, F.
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Westwood, N.
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Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 , Charalampopoulos, D. , Shaw, L. (2020) Valorisation of natural resources and the need for economic and sustainability sssessment: the case of cocoa pod husk in Indonesia. Sustainability , 12 (21). ISSN: 2071-1050 | doi: https://dx.doi.org/10.3390/su12218962
- Azman, E. , Charalampopoulos, D. , Chatzifragkou, A. (2020) Acetic acid buffer as extraction medium for free and bound phenolics from dried blackcurrant (Ribes nigrum L.) skins. Journal of Food Science , 85 (11). pp. 3745-3755. ISSN: 0022-1147 | doi: https://dx.doi.org/10.1111/1750-3841.15466
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Abukhabta, S.
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Khalil Ghawi, S.
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Karatzas, K.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , McDougall, G. , Allwood, J. , Verrall, S. , Lavery, S. , Latimer, C. , Pourshahidi, L. , Lawther, R. , O’Connor, G. , Rowland, I. , Gill, C. (2020) Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforaphane. European Journal of Nutrition ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-020-02322-0
- Albadran, H. , Monteagudo-Mera, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2020) Development of chitosan-coated agar-gelatin particles for probiotic delivery and targeted release in the gastrointestinal tract. Applied Microbiology and Biotechnology , 104 (13). pp. 5749-5757. ISSN: 0175-7598 | doi: https://dx.doi.org/10.1007/s00253-020-10632-w
- Harith, Z. , de Andrade Lima, M. , Charalampopoulos, D. , Chatzifragkou, A. (2020) Optimised production and extraction of astaxanthin from the yeast Xanthophyllomyces dendrorhous. Microorganisms , 8 (3). ISSN: 2076-2607 | doi: https://dx.doi.org/10.3390/microorganisms8030430
- Liu, C. , Kolida, S. , Charalampopoulos, D. , Rastall, R. (2020) An evaluation of the prebiotic potential of microbial levans from Erwinia sp. 10119. Journal of Functional Foods , 64 ISSN: 1756-4646 | doi: https://dx.doi.org/10.1016/j.jff.2019.103668
- Harris, S. , Powers, S. , Monteagudo, A. , Kosik, O. , Lovegrove, A. , Shewry, P. , Charalampopoulos, D. (2020) Determination of the prebiotic activity of wheat arabinogalactan peptide (AGP) using batch culture fermentation. European Journal of Nutrition , 59 pp. 297-307. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-019-01908-7
- Harris, S. , Monteagudo-Mera, A. , Kosik, O. , Charalampopoulos, D. , Shewry, P. , Lovegrove, A. (2019) Comparative prebiotic activity of mixtures of cereal grain polysaccharides. AMB Express , 9 (1). pp 0. ISSN: 2191-0855 | doi: https://dx.doi.org/10.1186/s13568-019-0925-z
- Min, J. , Reddy, L. , Charalampopoulos, D. , Kim, Y. , Wee, Y. (2019) Optimized production of Poly(γ-Glutamic acid) by bacillus sp. FBL-2 through response surface methodology using central composite design. Journal of Microbiology and Biotechnology , 29 (7). pp. 1061-1070. ISSN: 1017-7825 | doi: https://dx.doi.org/10.4014/jmb.1904.04013
- Song, D. , Reddy, V. , Charalampopoulos, D. , Wee, Y. (2019) Poly-(γ-glutamic acid) Production and Optimization from Agro-Industrial Bioresources as Renewable Substrates by Bacillus sp. FBL-2 through Response Surface Methodology. Biomolecules , 9 (12). ISSN: 2218-273X | doi: https://dx.doi.org/10.3390/biom9120754
- Zaini, N. , Chatzifragkou, A. , Charalampopoulos, D. (2019) Alkaline fractionation and enzymatic saccharification of wheat dried distillers grains with solubles (DDGS). Food and Bioproducts Processing , 118 pp. 103-113. ISSN: 0960-3085 | doi: https://dx.doi.org/10.1016/j.fbp.2019.09.006
- Harith, Z. , Charalampopoulos, D. , Chatzifragkou, A. (2019) Rapeseed meal hydrolysate as substrate for microbial astaxanthin production. Biochemical Engineering Journal , 151 ISSN: 1369-703X | doi: https://dx.doi.org/10.1016/j.bej.2019.107330
- Zaini, N. , Chatzifragkou, A. , Tverezovskiy, V. , Charalampopoulos, D. (2019) Purification and polymerisation of microbial D-lactic acid from DDGS hydrolysates fermentation. Biochemical Engineering Journal , 150 ISSN: 1369-703X | doi: https://dx.doi.org/10.1016/j.bej.2019.107265
- Monteagudo, A. , Rastall, B. , Gibson, G. , Charalampopoulos, D. , Chatzifragkou, A. (2019) Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Applied Microbiology and Biotechnology , 103 pp. 6463-6472. ISSN: 0175-7598 | doi: https://dx.doi.org/10.1007/s00253-019-09978-7
- de Andrade Lima, M. , Kestekoglou, I. , Charalampopoulos, D. , Chatzifragkou, A. (2019) Supercritical fluid extraction of carotenoids from vegetable waste matrices. Molecules , 24 (3). ISSN: 1420-3049 | doi: https://dx.doi.org/10.3390/molecules24030466
- Prasanna, P. and Charalampopoulos, D. (2019) Encapsulation in an alginate–goats’ milk–inulin matrix improves survival of probiotic Bifidobacterium in simulated gastrointestinal conditions and goats’ milk yoghurt. International Journal of Dairy Technology , 72 (1). pp. 132-141. ISSN: 1471-0307 | doi: https://dx.doi.org/10.1111/1471-0307.12568
- Mohd Zaini, N. , Chatzifragkou, A. , Charalampopoulos, D. (2019) Microbial production of D-lactic acid from dried distillers grains with solubles. Engineering in Life Sciences , 19 (1). pp. 21-30. ISSN: 1618-2863 | doi: https://dx.doi.org/10.1002/elsc.201800077
- Lu, F. , Rodriguez Garcia, J. , Van Damme, I. , Westwood, N. , Shaw, L. , Robinson, J. , Warren, G. , Chatzifragkou, A. , McQueen Mason, S. , Gomez, L. , Faas, L. , Balcombe, K. , Srinivasan, C. , Picchioni, F. , Hadley, P. , Charalampopoulos, D. (2018) Valorisation strategies for cocoa pod husk and its fractions. Current Opinion in Green and Sustainable Chemistry , 14 pp. 80-88. ISSN: 2452-2236 | doi: https://dx.doi.org/10.1016/j.cogsc.2018.07.007
- Si, J. , Jang, E. , Charalampopoulos, D. , Wee, Y. (2018) Purification and characterization of microbial protease produced extracellularly from Bacillus subtilis FBL-1. Biotechnology and Bioprocess Engineering , 23 (2). pp. 176-182. ISSN: 1226-8372 | doi: https://dx.doi.org/10.1007/s12257-017-0495-3
- Monteagudo, A. , Chatzifragkou, A. , Kosik, O. , Gibson, G. , Lovegrove, A. , Shewry, P. , Charalampopoulos, D. (2018) Evaluation of the prebiotic potential of arabinoxylans extracted from wheat distillers’ dried grains with solubles (DDGS) and in-process samples. Applied Microbiology and Biotechnology , 102 (17). pp. 7577-7587. ISSN: 0175-7598 | doi: https://dx.doi.org/10.1007/s00253-018-9171-6
- Granato, D. , Shahidi, F. , Wrolstad, R. , Kilmartin, P. , Melton, L. , Hidalgo, F. , Miyashita, K. , Camp, J. , Alasalvar, C. , Ismail, A. , Elmore, S. , Birch, G. , Charalampopoulos, D. , Astley, S. , Pegg, R. , Zhou, P. , Finglas, P. (2018) Antioxidant activity, total phenolics and flavonoids contents: should we ban in vitro screening methods?. Food Chemistry , 264 pp. 471-475. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2018.04.012
- Srisukchayakul, P. , Charalampopoulos, D. , Karatzas, K. (2018) Study on the effect of citric acid adaptation toward the subsequent survival of Lactobacillus plantarum NCIMB 8826 in low pH fruit juices during refrigerated storage. Food Research International , 111 pp. 198-204. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2018.05.018
- Prabhakumari, P. , Chatzifragkou, A. , Kosik, O. , Lovegrove, A. , Shewry, P. , Charalampopoulos, D. (2018) Development and characterisation of protein films derived from dried distillers’ grains with solubles and in-process samples. Industrial Crops and Products , 121 pp. 258-266. ISSN: 0926-6690 | doi: https://dx.doi.org/10.1016/j.indcrop.2018.05.016
- Chatzifragkou, A. and Charalampopoulos, D. (2018) Distiller's dried grains with solubles (DDGS) and intermediate products as starting materials in biorefinery strategies. In: Galanakis, C. , (eds.) Sustainable Recovery and Reutilization of Cereal Processing By-products. Elsevier , Amsterdam, Netherlands. pp. 63-86. ISBN: 9780081021620 | doi: https://dx.doi.org/10.1016/B978-0-08-102162-0.00003-4
- Albadran, H. , Chatzifragkou, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2018) Development of surfactant-coated alginate capsules containing Lactobacillus plantarum. Food Hydrocolloids , 82 pp. 490-499. ISSN: 0268-005X | doi: https://dx.doi.org/10.1016/j.foodhyd.2018.04.035
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de Andrade Lima, M.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 (2018) Purification of supercritical-fluid carotenoid-rich extracts by hydrophobic interaction chromatography. Separation and Purification Technology , 203 pp. 1-10. ISSN: 1383-5866 | doi: https://dx.doi.org/10.1016/j.seppur.2018.04.018
- Prasanna, P. and Charalampopoulos, D. (2018) Encapsulation of Bifidobacterium longum in alginate-dairy matrices and survival in simulated gastrointestinal conditions, refrigeration, cow milk and goat milk. Food Bioscience , 21 pp. 72-79. ISSN: 2212-4292 | doi: https://dx.doi.org/10.1016/j.fbio.2017.12.002
- Ho, A. , Kosik, O. , Lovegrove, A. , Charalampopoulos, D. , Rastall, R. (2018) In vitro fermentability of xylo-oligosaccharide and xylo-polysaccharide fractions with different molecular weights by human faecal bacteria. Carbohydrate Polymers , 179 pp. 50-58. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2017.08.077
- de Andrade Lima, M. , Charalampopoulos, D. , Chatzifragkou, A. (2018) Optimisation and modelling of supercritical CO2 extraction process of carotenoids from carrot peels. The Journal of Supercritical Fluids , 133 pp. 94-102. ISSN: 0896-8446 | doi: https://dx.doi.org/10.1016/j.supflu.2017.09.028
- Bepeyeva, A. , de Barros, J. , Albadran, H. , Kakimov, A. , Kakimova, Z. , Charalampopoulos, D. , Khutoryanskiy, V. (2017) Encapsulation of lactobacillus casei into calcium pectinate-chitosan beads for enteric delivery. Journal of Food Science , 82 (12). pp. 2954-2959. ISSN: 0022-1147 | doi: https://dx.doi.org/10.1111/1750-3841.13974
- Kosik, O. , Powers, S. , Chatzifragkou, A. , Prabhakumari, P. , Charalampopoulos, D. , Hess, L. , Brosnan, J. , Shewry, P. , Lovegrove, A. (2017) Changes in the arabinoxylan fraction of wheat grain during 1 alcohol production. Food Chemistry , 221 pp. 1754-1762. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2016.10.109
- Chatzifragkou, A. , Prabhakumari, P. , Charalampopoulos, D. (2016) Upgrading food processing side streams. In: Williams, P. and Phillips, G. , (eds.) Gums and Stabilisers for the Food Industry 18: Hydrocolloid Functionality for Affordable and Sustainable Global Food Solutions. Royal Society of Chemistry pp. 135-147. ISSN: 2042-0625 ISBN: 9781782623274 | doi: https://dx.doi.org/10.1039/9781782623830-00135
- Ramos, P. , Cerqueira, M. , Cook, M. , Bourbon, A. , Khutoryanskiy, V. , Charalampopoulos, D. , Teixeira, J. , Vicente, A. (2016) Development of an immobilization system for in situ micronutrients release. Food Research International , 90 pp. 121-132. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2016.10.050
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de Barros, J.
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Costabile, A.
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Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Khutoryanskiy, V. , Edwards, A. (2016) Evaluating and optimizing oral formulations of live bacterial vaccines using a gastro-small intestine model. European Journal of Pharmaceutics and Biopharmaceutics , 102 pp. 115-122. ISSN: 0939-6411 | doi: https://dx.doi.org/10.1016/j.ejpb.2016.03.010
- Chatzifragkou, A. , Prabhakumari, P. , Kosik, O. , Lovegrove, A. , Shewry, P. , Charalampopoulos, D. (2016) Extractability and characteristics of proteins deriving from wheat DDGS. Food Chemistry , 198 pp. 12-19. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2015.11.036
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Costabile, A.
,
Walton, G.
ORCID: 0000-0001-5426-5635 , Tzortzis, G. , Vulevic, J. , Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Gibson, G. (2015) Development of a bread delivery vehicle for dietary prebiotics to enhance food functionality targeted at those with metabolic syndrome. Gut Microbes , 6 (5). pp. 300-309. ISSN: 1949-0984 | doi: https://dx.doi.org/10.1080/19490976.2015.1064577
- Chatzifragkou, A. , Kosik, O. , Prabhakumari, P. , Lovegrove, A. , Frazier, R. , Shewry, P. , Charalampopoulos, D. (2015) Biorefinery strategies for upgrading Distillers’ Dried Grains with Solubles (DDGS). Process Biochemistry , 50 (12). pp. 2194-2207. ISSN: 0032-9592 | doi: https://dx.doi.org/10.1016/j.procbio.2015.09.005
- Sidira, M. , Kourkoutas, Y. , Kanellaki, M. , Charalampopoulos, D. (2015) In vitro study on the cell adhesion ability of immobilized lactobacilli on natural supports. Food Research International , 76 (3). pp. 532-539. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2015.07.036
- Albadran, H. , Chatzifragkou, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2015) Stability of probiotic Lactobacillus plantarum in dry microcapsules under accelerated storage conditions. Food Research International , 74 pp. 208-216. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2015.05.016
- de Barros, J. , Lechner, T. , Charalampopoulos, D. , Khutoryanskiy, V. , Edwards, A. (2015) Enteric coated spheres produced by extrusion/spheronization provide effective gastric protection and efficient release of live therapeutic bacteria. International Journal of Pharmaceutics , 493 (1-2). pp. 483-494. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2015.06.051
- Costabile, A. , Walton, G. , Tzortzis, G. , Vulevic, J. , Charalampopoulos, D. , Gibson, G. (2015) Effects of orange juice formulation on prebiotic functionality using an in vitro colonic model sytem. PLoS ONE , 10 (3). pp 0. ISSN: 1932-6203 | doi: https://dx.doi.org/10.1371/journal.pone.0121955
- Bhat, A. , Irorere, V. , Bartlett, T. , Hill, D. , Kedia, G. , Charalampopoulos, D. , Nualkaekul, S. , Radecka, I. (2015) Improving survival of probiotic bacteria using bacterial poly-γ-glutamic acid. International Journal of Food Microbiology , 196 pp. 24-31. ISSN: 0168-1605 | doi: https://dx.doi.org/10.1016/j.ijfoodmicro.2014.11.031
- Ho, A. , Carvalheiro, F. , Duarte, L. , Roseiro, L. , Charalampopoulos, D. , Rastall, R. (2014) Production and purification of xylooligosaccharides from oil palm empty fruit bunch fibre by a non-isothermal process. Bioresource Technology , 152 pp. 526-529. ISSN: 0960-8524 | doi: https://dx.doi.org/10.1016/j.biortech.2013.10.114
- Prasanna, P. , Grandison, A. , Charalampopoulos, D. (2014) Bifidobacteria in milk products: an overview of physiological and biochemical properties, exopolysaccharide production, selection criteria of milk products and health benefits. Food Research International , 55 pp. 247-262. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2013.11.013
- Cook, M. , Charalampopoulos, D. , Khutoryanskiy, V. (2014) Microencapsulation of probiotic bacteria into alginate hydrogels. In: Connon, C. and Hamley, I. , (eds.) Hydrogels in Cell-Based Therapies. RSC soft matter series Royal Society of Chemistry , Cambridge. pp. 95-111. ISBN: 9781782621263
- de Barros, J. , Scherer, T. , Charalampopoulos, D. , Khutoryanskiy, V. , Edwards, A. (2014) A laminated polymer film formulation for enteric delivery of live vaccine and probiotic bacteria. Journal of Pharmaceutical Sciences , 103 (7). pp. 2022-2032. ISSN: 1520-6017 | doi: https://dx.doi.org/10.1002/jps.23997
- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2014) Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gels. International Journal of Pharmaceutics , 466 (1-2). pp. 400-408. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2014.03.034
- Osman, A. , Symeou, S. , Trisse, V. , Watson, K. , Tzortzis, G. , Charalampopoulos, D. (2014) Synthesis of prebiotic galactooligosaccharides from lactose using bifidobacterial β-galactosidase (BbgIV) immobilised on DEAE-Cellulose, Q-Sepharose and amino-ethyl agarose. Biochemical Engineering Journal , 82 pp. 188-199. ISSN: 1369-703X | doi: https://dx.doi.org/10.1016/j.bej.2013.11.020
- Bhat, A. , Irorere, V. , Bartlett, T. , Hill, D. , Kedia, G. , Morris, M. , Charalampopoulos, D. , Radecka, I. (2013) Bacillus subtilis natto: a non-toxic source of poly-γ-glutamic acid that could be used as a cryoprotectant for probiotic bacteria. AMB Express , 3 (1). pp. 36. ISSN: 2191-0855 | doi: https://dx.doi.org/10.1186/2191-0855-3-36
- Osman, A. , Tzortzis, G. , Rastall, R. , Charalampopoulos, D. (2013) High yield production of a soluble bifidobacterial β-galactosidase (BbgIV) inE. coliDH5α with improved catalytic efficiency for the synthesis of prebiotic galactooligosaccharides. Journal of Agricultural and Food Chemistry , 61 (9). pp. 2213-2223. ISSN: 0021-8561 | doi: https://dx.doi.org/10.1021/jf304792g
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- Cook, M. , Saratoon, T. , Tzortzis, G. , Edwards, A. , Charalampopoulos, D. , Khutoryanskiy, V. (2013) CLSM method for the dynamic observation of pH change within polymer matrices for oral delivery. Biomacromolecules , 14 (2). pp. 387-393. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm301569r
- Prasanna, P. , Grandison, A. , Charalampopoulos, D. (2013) Microbiological, chemical and rheological properties of low fat set yoghurt produced with exopolysaccharide (EPS) producing Bifidobacterium strains. . Food Research International , 51 (1). pp. 15-22. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2012.11.016
- Cook, M. , Tzortzis, G. , Khutoryanskiy, V. , Charalampopoulos, D. (2013) Layer-by-layer coating of alginate matrices with chitosan–alginate for the improved survival and targeted delivery of probiotic bacteria after oral administration. Journal of Materials Chemistry B , 1 pp. 52-60. | doi: https://dx.doi.org/10.1039/C2TB00126H
- Nualkaekul, S. , Deepika, G. , Charalampopoulos, D. (2012) Survival of freeze dried Lactobacillus plantarum in instant fruit powders and reconstituted fruit juices. Food Research International , 48 (2). pp. 627-633. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2012.06.003
- Nualkaekul, S. , Lenton, D. , Cook, M. , Khutoryanskiy, V. , Charalampopoulos, D. (2012) Chitosan coated alginate beads for the survival of microencapsulated Lactobacillus plantarum in pomegranate juice. Carbohydrate Polymers , 90 (3). pp. 1281-1287. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2012.06.073
- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2012) Microencapsulation of probiotics for gastrointestinal delivery. Journal of Controlled Release , 162 (1). pp. 56-67. ISSN: 0168-3659 | doi: https://dx.doi.org/10.1016/j.jconrel.2012.06.003
- Prasanna, P. , Bell, A. , Grandison, A. , Charalampopoulos, D. (2012) Emulsifying, rheological and physicochemical properties of exopolysaccharide produced by Bifidobacterium longum subsp. infantis CCUG 52486 and Bifidobacterium infantis NCIMB 702205. Carbohydrate Polymers , 90 (1). pp. 533-540. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2012.05.075
- Deepika, G. , Karunakaran, E. , Hurley, C. , Biggs, C. , Charalampopoulos, D. (2012) Influence of fermentation conditions on the surface properties and adhesion of Lactobacillus rhamnosus GG. Microbial Cell Factories , 11 (1). ISSN: 1475-2859 | doi: https://dx.doi.org/10.1186/1475-2859-11-116
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- Charalampopoulos, D. and Rastall, R. (2012) Prebiotics in foods. Current Opinion in Biotechnology , 23 (2). pp. 187-191. ISSN: 0958-1669 | doi: https://dx.doi.org/10.1016/j.copbio.2011.12.028
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- Prasanna, P. , Grandison, A. , Charalampopoulos, D. (2012) Screening human intestinal Bifidobacterium strains for growth, acidification, EPS production and viscosity potential in low-fat milk. International Dairy Journal , 23 (1). pp. 36-44. ISSN: 0958-6946 | doi: https://dx.doi.org/10.1016/j.idairyj.2011.09.008
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- Deepika, G. , Rastall, R. , Charalampopoulos, D. (2011) Effect of food models and low-temperature storage on the adhesion of Lactobacillus rhamnosus GG to Caco-2 cells. Journal of Agricultural and Food Chemistry , 59 (16). pp. 8661-8666. ISSN: 0021-8561 | doi: https://dx.doi.org/10.1021/jf2018287
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- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2011) Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteria. Biomacromolecules , 12 (7). pp. 2834-2840. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm200576h
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- Charalampopoulos, D. and Pandiella, S. (2010) Survival of human derived Lactobacillus plantarum in fermented cereal extracts during refrigerated storage. LWT - Food Science and Technology , 43 (3). pp. 431-435. ISSN: 0023-6438 | doi: https://dx.doi.org/10.1016/j.lwt.2009.09.006
- Deepika, G. and Charalampopoulos, D. (2010) Surface and adhesion properties of lactobacilli. In: Laskin, A. , Sariaslani, S. , Gadd, G. , (eds.) Advances in Applied Microbiology . , 70. Advances in Applied MIcrobiology , 70 pp. 127-152. ISBN: 9780123809919 | doi: https://dx.doi.org/10.1016/S0065-2164(10)70004-6
- Ampatzoglou, A. , Schurr, B. , Deepika, G. , Baipong, S. , Charalampopoulos, D. (2010) Influence of fermentation on the acid tolerance and freeze drying survival of Lactobacillus rhamnosus GG. Biochemical Engineering Journal , 52 (1). pp. 65-70. ISSN: 1369-703X | doi: https://dx.doi.org/10.1016/j.bej.2010.07.005
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- Kedia, . , Vazquez, . , Charalampopoulos, . , Pandiella, . (2009) In vitro fermentation of oat bran obtained by debranning with a mixed culture of human fecal bacteria. Current Microbiology , 58 (4). pp. 338-342. ISSN: 0343-8651 | doi: https://dx.doi.org/10.1007/s00284-008-9335-1
- Rozada, . , Vazquez, . , Charalampopoulos, . , Thomas, . , Pandiella, . (2009) Effect of storage temperature and media composition on the survivability of Bifidobacterium breve NCIMB 702257 in a malt hydrolisate. International Journal of Food Microbiology , 133 (1-2). pp. 14-21. ISSN: 0168-1605 | doi: https://dx.doi.org/10.1016/j.ijfoodmicro.2009.04.003
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- Deepika, G. , Green, R. , Frazier, R. , Charalampopoulos, D. (2009) Effect of growth time on the surface and adhesion properties of Lactobacillus rhamnosus GG. Journal of Applied Microbiology , 107 (4). pp. 1230-1240. ISSN: 1364-5072 | doi: https://dx.doi.org/10.1111/j.1365-2672.2009.04306.x