Charlotte Mills
-
+44 (0) 118 378 7108
-
Hugh Sinclair Lecturer in Nutritional Sciences
- Examinations Officer
Office
2-43Building location
Harry NurstenAreas of interest
My research employs a multidisciplinary approach, combining clinical and basic/analytical science to investigate the impact of plant bioactives and other nutrients on cardiometabolic health and the mechanisms underpinning these effects.
I am specifically interested in methods for maximising beneficial health effects e.g. through food processing and synergy. As well as the cross-talk between the gut microbiota, metabolism and health outcomes.
Research centres and groups
- Nutrition Research Group.
Publications
- Cahyana, Y. , Mills, C. , Huda, S. , Gordon, M. (2022) Factors affecting cellular uptake of anthocyanins: the role of pH, glucose and anthocyanin structure. Nutrients , 14 (22). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu14224807
- Visiolo, F. , Bordereau, V. , van der Kamp, M. , Clegg, M. , Guo, J. , Dolores del Castillo, M. , Gilcrease, W. , Hollywood, A. , Iriondo-DeHond, A. , Mills, C. , Sciascia, S. , van Zutphen, T. , Visser, E. , Willett, W. (2022) Educating health care professionals on the importance of proper diets. An online course on nutrition, health and sustainability. International Journal of Food Science and Nutrition , 73 (8). pp. 1091-1095. ISSN: 1465-3478 | doi: https://dx.doi.org/10.1080/09637486.2022.2123908
- Kirkham, F. , Mills, C. , Fantin, F. , Tatsuno, I. , Nagayama, D. , Giani, A. , Zamboni, M. , Shirai, K. , Cruickshank, J. , Rajkumar, C. (2022) Are you as old as your arteries? Comparing arterial aging in Japanese and European patient groups using cardio-ankle vascular index. Journal of Hypertension , 40 (9). pp. 1758-1767. ISSN: 1473-5598 | doi: https://dx.doi.org/10.1097/HJH.0000000000003214
- Morselli, F. , Faconti, L. , Mills, C. , Morant, S. , Chowienczyk, P. , Yeung, J. , Cavarape, A. , Cruickshank, J. , Webb, A. (2021) Dietary nitrate prevents progression of carotid subclinical atherosclerosis through blood pressure-independent mechanisms in patients with or at risk of type 2 diabetes mellitus. British Journal of Clinical Pharmacology , 87 (12). ISSN: 0306-5251 | doi: https://dx.doi.org/10.1111/bcp.14897
- Mills, C. , Harding, S. , Bapir, M. , Mandalari, G. , Salt, L. , Gray, R. , Fielding, B. , Wilde, P. , Hall, W. , Berry, S. (2021) Palmitic acid-rich oils with and without interesterification lower postprandial lipemia and increase atherogenic lipoproteins compared to a MUFA-rich oil: a randomized controlled trial. American Journal of Clinical Nutrition , 113 (5). pp. 1221-1231. ISSN: 0002-9165 | doi: https://dx.doi.org/10.1093/ajcn/nqaa413
-
O'Gallagher, K.
ORCID: 0000-0003-2218-4763
,
Cardona, S.
,
Hill, C.
,
Al-Saedi, A.
,
Shahed, F.
,
Floyd, C.
ORCID: 0000-0001-9359-6381
,
McNeil, K.
,
Mills, C.
ORCID: 0000-0002-8313-3700
,
Webb, A.
ORCID: 0000-0002-8109-1877
(2021)
Grapefruit juice enhances the systolic blood pressure-lowering effects of dietary nitrate-containing beetroot juice.
British Journal of Clinical Pharmacology
, 87
(2).
pp.
577-587.
ISSN:
0306-5251
|
doi:
https://dx.doi.org/10.1111/bcp.14420
- Floyd, C. , Shahed, F. , Ukah, F. , McNeil, K. , O'Gallagher, K. , Mills, C. , Evangelopoulos, D. , Lim, S. , Mudway, I. , Barrett, B. , Walton, H. , Webb, A. (2020) Acute blood pressure-lowering effects of nitrogen dioxide exposure from domestic gas cooking via elevation of plasma nitrite concentration in healthy individuals. Circulation Research , 127 (6). pp. 847-848. ISSN: 0009-7330 | doi: https://dx.doi.org/10.1161/CIRCRESAHA.120.316748
- Mills, C. , Govini, V. , Faconti, L. , Casagrande, M. , Morant, S. , Crickmore, H. , Iqbal, F. , Maskell, P. , Masani, A. , Nanino, E. , Webb, A. , Cruickshank, J. (2020) A randomised, factorial trial to reduce arterial stiffness independently of blood pressure: proof of concept? The ‘VaSera’ trial testing dietary nitrate and spironolactone. British Journal of Clinical Pharmacology , 86 (5). pp. 891-902. ISSN: 0306-5251 | doi: https://dx.doi.org/10.1111/bcp.14194
- Sayers, S. , Beavil, R. , Nicholas, F. , Huang, G. , Choudhary, P. , Pacholarz, K. , Barran, P. , Mills, C. , Cruickshank, J. , Silvestre, M. , Poppit, S. , McGill, A. , Lavery, G. , Hodson, D. , Caton, P. (2020) Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta- cell dysfunction in type 2 diabetes. Diabetologia , 63 (2). pp. 313-323. ISSN: 0012-186X | doi: https://dx.doi.org/10.1007/s00125-019-05029-y
- Rodriguez-Mateos, A. , Istas, G. , Boschek, L. , Feliciano, R. , Mills, C. , Boby, C. , Gomez-Alonso, S. , Milenkovic, D. , Heiss, C. (2019) Circulating anthocyanin metabolites mediate vascular benefits of blueberries: insights from randomized controlled trials, metabolomics, and nutrigenomics. Journals of Gerontology Series A: Biological and Medical Sciences , 74 (7). pp. 967-976. ISSN: 1079-5006 | doi: https://dx.doi.org/10.1093/gerona/glz047
- Webster, L. , Myers, J. , Nelson-Piercy, C. , Mills, C. , Watt-Coote, I. , Khalil, A. , Seed, P. , Kennedy Cruickshank, J. , Chappell, L. (2019) Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study. Ultrasound in Obstetrics & Gynecology , 53 (5). pp. 638-648. ISSN: 9607692 | doi: https://dx.doi.org/10.1002/uog.19021
- Faconti, L. , Mills, C. , Govoni, V. , Gu, H. , Morant, S. , Jiang, B. , Cruickshank, J. , Webb, A. (2019) Cardiac effects of 6 months’ dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double-blind, randomised-controlled, VASERA TRIAL. British Journal of Clinical Pharmacology , 85 (1). pp. 169-180. ISSN: 0306-5251 | doi: https://dx.doi.org/10.1111/bcp.13783
- Ferriday, D. , Grundy, M. , Mills, C. (2018) The benefits of the Biotechnology and Biological Sciences Research Council (BBSRC) Diet and Health Research Industry Club (DRINC) to early career researchers working in food, nutrition and human health. Nutrition Bulletin , 43 (4). pp. 435-441. ISSN: 1471-9827 | doi: https://dx.doi.org/10.1111/nbu.12353
- Mills, C. , Hall, W. , Berry, S. (2017) What are interesterified fats and should we be worried about them in our diet?. Nutrition Bulletin , 42 (2). pp. 153-158. ISSN: 1471-9827 | doi: https://dx.doi.org/10.1111/nbu.12264
- Khatri, J. , Mills, C. , Maskell, P. , Odongerel, C. , Webb, A. (2017) It is rocket science - why dietary nitrate is hard to ‘beet’! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway. British Journal of Clinical Pharmacology , 83 (1). pp. 129-139. ISSN: 0306-5251 | doi: https://dx.doi.org/10.1111/bcp.12913
- Mills, C. , Khatri, J. , Maskell, P. , Odongerel, C. , Webb, A. (2017) It is rocket science - why dietary nitrate is hard to ‘beet’! Part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway. British Journal of Clinical Pharmacology , 83 (1). pp. 140-151. ISSN: 0306-5251 | doi: https://dx.doi.org/10.1111/bcp.12918
- Feliciano, R. , Mills, C. , Istas, G. , Heiss, C. , Rodriguez-Mateos, A. (2017) Absorption, metabolism and excretion of cranberry (poly)phenols in humans: a dose response study and assessment of inter-individual variability. Nutrients , 9 (3). pp. 268. ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu9030268
- Mills, C. , Govoni, V. , Faconti, L. , Casagrande, M. , Morant, S. , Webb, A. , Cruickshank, J. (2017) Reducing arterial stiffness independently of blood pressure: the VaSera trial. Journal of the American College of Cardiology , 70 (13). pp. 1683-1684. ISSN: 0735-1097 | doi: https://dx.doi.org/10.1016/j.jacc.2017.07.765
- Mills, C. , Flury, A. , Marmet, C. , Poquet, L. , Rimaldi, S. , Sartori, C. , Rexhag, E. , Brenner, R. , Allman, Y. , Zimmerman, D. , Gibson, G. , Mottram, D. , Oruna-Concha, M. , Actis-Goretta, L. , Spencer, J. (2017) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: two randomized, controlled, crossover intervention trials. Clinical Nutrition , 36 (6). pp. 1520-1529. ISSN: 0261-5614 | doi: https://dx.doi.org/10.1016/j.clnu.2016.11.013
- Faconti, L. , Nanino, E. , Mills, C. , Cruickshank, K. (2016) Do arterial stiffness and wave reflection underlie cardiovascular risk in ethnic minorities?. JRSM Cardiovascular Disease , 5 pp. 1-9. ISSN: 2048-0040 | doi: https://dx.doi.org/10.1177/2048004016661679
- Yeboah, K. , Antwi, D. , Gyan, B. , Govoni, V. , Mills, C. , Cruickshank, J. , Amoah, A. (2016) Arterial stiffness in hypertensive and type 2 diabetes patients in Ghana: comparison of the cardio-ankle vascular index and central aortic techniques. BMC Endocrine Disorders , 16 (53). ISSN: 1472-6823 | doi: https://dx.doi.org/10.1186/s12902-016-0135-5
- Mills, C. , Govoni, V. , Casagrande, M. , Faconti, L. , Webb, A. , Cruickshank, J. (2015) Design and progress of a factorial trial testing the effect of spironolactone and inorganic nitrate on arterial function in people at risk of or with type 2 diabetes. Artery Research , 12 pp. 48-53. ISSN: 18729312 | doi: https://dx.doi.org/10.1016/j.artres.2015.10.194
- Mills, C. , Touzonis, X. , Oruna-Concha, M. , Mottram, D. , Gibson, G. , Spencer, J. (2015) In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth. British Journal of Nutrition , 113 (8). pp. 1220-1227. ISSN: 0007-1145 | doi: https://dx.doi.org/10.1017/S0007114514003948
- Mills, C. , Oruna-Concha, M. , Mottram, D. , Gibson, G. , Spencer, J. (2013) The effect of processing on chlorogenic acid content of commercially available coffee. Food Chemistry , 141 (4). pp. 3335-3340. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2013.06.014
- Mottram, D. , Mills, C. , Wagstaff, C. , Dodson, A. (2011) Investigation of the characteristic earthy flavor of baby corn (Zea Mays). In: Hofmann, . , Meyerhof, . , Schieberle, . , (eds.) Advances and Challenges in Flavor Chemistry & Biology. Deutsche Forschungsanstalt für Lebensmittelchemie , Freising, Germany. pp. 146-151. ISBN: 9783938896389