About the servers

This is the main page for the McGuffin bioinformatics group web servers. Several protein structure and function prediction methods are freely available for academic use. Please cite the relevant publications for each method. References for methods can be found on each server home page.

IntFOLD

An integrated server providing a single interface for the prediction of structure and function from sequence with interactive graphical output.

FunFOLD

Predict protein-ligand interactions.

nFOLD3

Build 3D models of a protein from sequence using fold recognition.

ModFOLD

Assess the quality of predicted 3D models.

DomFOLD

Predict the domain boundaries within a protein sequence.

DISOclust

Predict the intrinsically disordered regions within a protein sequence.

Downloads

Download standalone verisons of the methods.
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Updates

  • March 2012: New hardware has been installed for benchmarking the new versions of our methods. The IntFOLD2 server is coming soon...
  • March 2012: Paper published in Biochemical Journal - the IntFOLD server was used for modelling Ste20-related kinase 3 (MST3). Publications
  • Sept 2011: Confidence scores (p-values) now included in IntFOLD-TS graphical output.
  • Aug 2011: Interactive IntFOLD-TS output now includes model-template superpositions.
  • May 2011: IntFOLD-TS method paper now in press - Publications
  • May 2011: FunFOLD paper now in press -Download Publications
  • March 2011: IntFOLD server paper now in press - Publications
  • March 2011: Methods paper describing application of servers to Blumeria proteome is now in press - Publications
  • Dec 2010: Success at CASP9. More details and new servers coming soon...

Contact

Tel: 0118 378 6332

Email: l.j.mcguffin
@reading.ac.uk

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