Vitaliy Khutoryanskiy

-
+44 (0) 118 378 6119
-
Professor of Formulation Science and Royal Society Industry Fellow
- Programme Director of MSc by Research in Pharmacy
- Module convenor of Research Methods and Advanced Topics (PMMR1) and Research Project in Advanced Topics (PMMRP)
Areas of interest
- Polymers for pharmaceutical applications
- Mucoadhesive drug delivery systems
- Transmucosal drug delivery (ocular, nasal, oral, intravesical and vaginal)
- Water-soluble and amphiphilic polymers
- Hydrogels, biomaterials & polymeric blends
- Functionalised nanoparticles (polymers, silica, gold)
- Stimuli-responsive polymers
- Invertebrate in vivo models in evaluation of toxicity and biological activities of chemicals and formulations (planaria and slugs)
Publications
- Vildanova, R. , Petrova, S. , Kolesov, S. , Khutoryanskiy, V. (2023) Biodegradable hydrogels based on chitosan and pectin for cisplatin delivery. Gels , 9 (4). ISSN: 2310-2861 | doi: https://dx.doi.org/10.3390/gels9040342
- Kashapova, N. , Kashapov, R. , Ziganshina, A. , Nikitin, D. , Semina, I. , Salnikov, V. , Khutoryanskiy, V. , Moustafine, R. , Zakharova, L. (2023) Cataleptogenic effect of haloperidol formulated in water-soluble calixarene-based nanoparticles. Pharmaceutics , 15 (3). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics15030921
- Semina, I. , Baichurina, A. , Nikitin, D. , Nikitina, A. , Moustafine, R. , Khutoryanskiy, V. (2023) Behavioral pharmacology as the main approach to study the efficiency of potential psychotropic drugs: analysis of modern methods (review). Drug development & registration , 12 (1). pp. 161-181. ISSN: 2658-5049 | doi: https://dx.doi.org/10.33380/2305-2066-2023-12-1-161-181
- Aspinall, S. and Khutoryanskiy, V. (2023) Surface modification of silica particles with adhesive functional groups or their coating with chitosan to improve the retention of toothpastes in the mouth. Langmuir , 39 (4). pp. 1677-1685. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/acs.langmuir.2c03269
- Onugwu, A. , Nwagwu, C. , Onugwu, O. , Echezona, A. , Agbo, C. , Ihim, S. , Emeh, P. , Nnamani, P. , Attama, A. , Khutoryanskiy, V. (2023) Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases. Journal of Controlled Release , 354 pp. 465-488. ISSN: 0168-3659 | doi: https://dx.doi.org/10.1016/j.jconrel.2023.01.018
- Vandera, K. , Pague, C. , Omar, J. , González-Gaitano, G. , Ways, T. , Khutoryanskiy, V. , Dreiss, C. (2023) Formation of supramolecular gels from host-guest interactions between PEGylated chitosan and α-cyclodextrin. Macromolecular Materials and Engineering ISSN: 1439-2054 | doi: https://dx.doi.org/10.1002/mame.202200646
-
Buang, F.
,
Chatzifragkou, A.
ORCID: 0000-0002-9255-7871 , Amin, M. , Khutoryanskiy, V. (2022) Synthesis of methacryloylated hydroxyethylcellulose and development of mucoadhesive wafers for buccal drug delivery. Polymers , 15 (1). ISSN: 2073-4360 | doi: https://dx.doi.org/10.3390/polym15010093
-
Soradech, S.
,
Kengkwasingh, P.
,
Williams, A.
ORCID: 0000-0003-3654-7916 , Khutoryanskiy, V. (2022) Synthesis and evaluation of poly(3-hydroxypropyl ethylene-imine) and its blends with chitosan forming novel elastic films for delivery of haloperidol. Pharmaceutics , 14 (12). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics14122671
- Moiseev, R. , Kaldybekov, D. , Filippov, S. , Radulescu, A. , Khutoryanskiy, V. (2022) Maleimide-decorated PEGylated mucoadhesive liposomes for ocular drug delivery. Langmuir , 38 (45). pp. 13870-13879. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/acs.langmuir.2c02086
-
Soradech, S.
,
Williams, A.
ORCID: 0000-0003-3654-7916 , Khutoryanskiy, V. (2022) Physically cross-linked cryogels of linear polyethyleneimine: influence of cooling temperature and solvent composition. Macromolecules , 55 (21). pp. 9537-9546. ISSN: 0024-9297 | doi: https://dx.doi.org/10.1021/acs.macromol.2c01308
- Tatykhanova, G. , Aseyev, V. , Vamvakaki, M. , Khutoryanskiy, V. , Kudaibergenov, S. (2022) Ophthalmic drug delivery system based on the complex of gellan and ofloxacin. Chemical Bulletin of Kazakh National University , 105 (2). pp. 4-12. ISSN: 2312-7554 | doi: https://dx.doi.org/10.15328/cb1239
- Ways, T. , Filippov, S. , Maji, S. , Glassner, M. , Cegłowski, M. , Hoogenboom, R. , King, S. , Lau, W. , Khutoryanskiy, V. (2022) Mucus-penetrating nanoparticles based on chitosan grafted with various non-ionic polymers: synthesis, structural characterisation and diffusion studies. Journal of Colloid and Interface Science , 626 pp. 251-264. ISSN: 0021-9797 | doi: https://dx.doi.org/10.1016/j.jcis.2022.06.126
- Onugwu, A. , Attama, A. , Nnamani, P. , Onugwu, S. , Onuigbo, E. , Khutoryanskiy, V. (2022) Development and optimization of solid lipid nanoparticles coated with chitosan and poly(2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin. Journal of Drug Delivery Science and Technology , 74 ISSN: 1773-2247 | doi: https://dx.doi.org/10.1016/j.jddst.2022.103527
- Brotherton, E. , Neal, T. , Kaldybekov, D. , Smallridge, M. , Khutoryanskiy, V. , Armes, S. (2022) Aldehyde-functional thermoresponsive diblock copolymer worm gels exhibit strong mucoadhesion. Chemical Science , 13 (23). pp. 6888-6898. ISSN: 1478-6524 | doi: https://dx.doi.org/10.1039/D2SC02074B
- Moiseev, R. , Steele, F. , Khutoryanskiy, V. (2022) Polyaphron formulations stabilised with different water-soluble polymers for ocular drug delivery. Pharmaceutics , 14 (5). pp. 1-20. ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics14050926
- Constantinou, A. , Nele, V. , Doutch, J. , Correia, J. , Moiseev, R. , Cihova, M. , Gaboriau, D. , Krell, J. , Khutoryanskiy, V. , Stevens, M. , Georgiou, T. (2022) Investigation of the thermogelation of a promising biocompatible ABC triblock terpolymer and its comparison with pluronic F127. Macromolecules , 55 (5). pp. 1783-1799. ISSN: 0024-9297 | doi: https://dx.doi.org/10.1021/acs.macromol.1c02123
- Makhayeva, D. , Filippov, S. , Yestemes, S. , Irmukhametova, G. , Khutoryanskiy, V. (2022) Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties. European Polymer Journal , 165 ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2022.111005
- Kazybayeva, D. , Irmukhametova, G. , Khutoryanskiy, V. (2022) Thiol-ene “click reactions” as a promising approach to polymer materials. Polymer Science, Series B , 64 pp. 1-16. ISSN: 1555-6123 | doi: https://dx.doi.org/10.1134/S1560090422010055
-
Bull, S.
ORCID: 0000-0001-5129-1731 , Khutoryanskiy, V. , Parker, J.
ORCID: 0000-0003-4121-5481 , Faka, M. , Methven, L. (2022) Oral retention of thermally denatured whey protein: In vivo measurement and structural observations by CD and NMR.. Food Chemistry , 374 pp 0. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2021.131650
- Haddow, P. , da Silva, M. , Kaldybekov, D. , Dreiss, C. , Hoffman, E. , Hutter, V. , Khutoryanskiy, V. , Kirton, S. , Mahmoudi, N. , McAuley, W. , Cook, M. (2022) Polymer architecture effects on poly(N,N-Diethyl acrylamide)-b-poly(ethylene glycol)-b-poly(N,N-diethyl acrylamide) thermoreversible gels and their evaluation as a healthcare material. Macromolecular Bioscience , 22 (3). ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.202100432
- Hock, N. , Racaniello, G. , Aspinall, S. , Denora, N. , Khutoryanskiy, V. , Bernkop-Schnürch, A. (2022) Thiolated nanoparticles for biomedical applications: mimicking the workhorses of our body. Advanced Science , 9 (1). ISSN: 2198-3844 | doi: https://dx.doi.org/10.1002/advs.202102451
- Morrison, P. and Khutoryanskiy, V. (2021) Controlled Drug Delivery via the Ocular Route. In: Benson, H. , Roberts, M. , Williams, A. , Liang, X. , (eds.) Fundamentals of Drug Delivery. Wiley pp. 349-375. ISBN: 9781119769644 | doi: https://dx.doi.org/10.1002/9781119769644.ch14
- Filippov, S. , Khusnutdinov, R. , Inham, W. , Liu, C. , Nikitin, D. , Semina, I. , Garvey, C. , Nasibullin, S. , Khutoryanskiy, V. , Zhang, H. , Moustafine, R. (2021) Hybrid nanoparticles for haloperidol encapsulation: quid est optimum?. Polymers , 13 (23). ISSN: 2073-4360 | doi: https://dx.doi.org/10.3390/polym13234189
-
Shan, X.
,
Aspinall, S.
,
Kaldybekov, D.
,
Buang, F.
,
Williams, A.
ORCID: 0000-0003-3654-7916 , Khutoryanskiy, V. (2021) Synthesis and evaluation of methacrylated poly(2-ethyl-2-oxazoline) as a mucoadhesive polymer for nasal drug delivery. ACS Applied Polymer Materials , 3 (11). pp. 5882-5892. ISSN: 2637-6105 | doi: https://dx.doi.org/10.1021/acsapm.1c01097
-
Aspinall, S.
ORCID: 0000-0002-1333-1664 , Parker, J.
ORCID: 0000-0003-4121-5481 , Khutoryanskiy, V.
ORCID: 0000-0002-7221-2630 (2021) Role of mucoadhesive polymers in retention of toothpaste in the oral cavity. Colloids and Surfaces B: Biointerfaces , 208 ISSN: 0927-7765 | doi: https://dx.doi.org/10.1016/j.colsurfb.2021.112104
- Kashapov, R. , Kashapova, N. , Ziganshina, A. , Syakaev, V. , Khutoryanskiy, V. , Zakharova, L. (2021) Interaction of mucin with viologen and acetate derivatives of calix[4]resorcinols. Colloids and Surfaces B: Biointerfaces , 208 ISSN: 9277765 | doi: https://dx.doi.org/10.1016/j.colsurfb.2021.112089
- Porfiryeva, N. , Semina, I. , Salakhov, I. , Moustafine, R. , Khutoryanskiy, V. (2021) Mucoadhesive and mucus-penetrating Interpolyelectrolyte complexes for nose-to-brain drug delivery. Nanomedicine: Nanotechnology, Biology and Medicine ISSN: 1549-9634 | doi: https://dx.doi.org/10.1016/j.nano.2021.102432
-
Shan, X.
,
Moghul, M.
,
Williams, A.
ORCID: 0000-0003-3654-7916 , Khutoryanskiy, V. (2021) Mutual Effects of Hydrogen Bonding and Polymer Hydrophobicity on Ibuprofen Crystal Inhibition in Solid Dispersions with Poly(N-vinyl pyrrolidone) and Poly(2-oxazolines). Pharmaceutics , 13 (5). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics13050659
- Nurgaziyeva, E. , Kudaibergenov, S. , Mun, G. , Khutoryanskiy, V. (2021) Synthesis of fluorescently-labelled poly(2-ethyl-2-oxazoline)-protected gold nanoparticles. Chemical Bulletin of Kazakh National University , 100 (1). pp. 12-20. ISSN: 2312-7554 | doi: https://dx.doi.org/10.15328/cb1185
- Lavikainen, J. , Dauletbekova, M. , Toleutay, G. , Kaliva, M. , Chatzinikolaidou, M. , Kudaibergenov, S. , Tenkovtsev, A. , Khutoryanskiy, V. , Vamvakaki, M. , Aseyev, V. (2021) Poly(2‐ethyl‐2‐oxazoline) grafted gellan gum for potential application in transmucosal drug delivery. Polymers for Advanced Technologies , 32 (7). pp. 2770-2780. ISSN: 1042-7147 | doi: https://dx.doi.org/10.1002/pat.5298
-
Ta, L.
,
Bujna, E.
,
Kun, S.
,
Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Khutoryanskiy, V. (2021) Electrosprayed mucoadhesive alginate-chitosan microcapsules for gastrointestinal delivery of probiotics. International Journal of Pharmaceutics , 597 ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2021.120342
-
Shah, S.
,
Khutoryanskiy, V.
,
Williams, A.
ORCID: 0000-0003-3654-7916 (2021) A novel polymer insect repellent conjugate for extended release and decreased skin permeation of Para-Menthane-3,8-Diol. Pharmaceutics , 13 (3). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics13030403
-
Viktorova, A.
ORCID: 0000-0001-9849-1968 , Elizarova, E.
ORCID: 0000-0001-9264-9576 , Romanova, R.
ORCID: 0000-0001-9454-2895 , Timergalieva, V.
ORCID: 0000-0002-3690-8905 , Khutoryanskiy, V.
ORCID: 0000-0002-7221-2630 , Moustafine, R.
ORCID: 0000-0002-0916-2853 (2021) Interpolymer complexes based on Carbopol<sup>®</sup> and poly(2-ethyl-2-oxazoline) as carriers for buccal delivery of metformin. Drug development & registration , 10 (1). pp. 48-55. ISSN: 2658-5049 | doi: https://dx.doi.org/10.33380/2305-2066-2021-10-1-48-55
-
Mansfield, E.
,
Filippov, S.
,
de la Rosa, V.
,
Cook, M.
,
Grillo, I.
,
Hoogenboom, R.
,
Williams, A.
ORCID: 0000-0003-3654-7916 , Khutoryanskiy, V. (2021) Understanding the temperature induced aggregation of silica nanoparticles decorated with temperature-responsive polymers: can a small step in the chemical structure make a giant leap for a phase transition?. Journal of Colloid and Interface Science , 590 pp. 249-259. ISSN: 0021-9797 | doi: https://dx.doi.org/10.1016/j.jcis.2021.01.044
- Makhayeva, D. , Irmukhametova, G. , Khutoryanskiy, V. (2021) Polymeric iodophors: preparation, properties, and biomedical applications. Review Journal of Chemistry , 10 pp. 40-57. ISSN: 2634-8284 | doi: https://dx.doi.org/10.1134/S2079978020010033
-
Aspinall, S.
,
Parker, J.
ORCID: 0000-0003-4121-5481 , Khutoryanskiy, V. (2021) Oral care product formulations, properties and challenges. Colloids and Surfaces B: Biointerfaces , 200 ISSN: 0927-7765 | doi: https://dx.doi.org/10.1016/j.colsurfb.2021.111567
-
Al Mahrooqi, J.
,
Khutoryanskiy, V.
,
Williams, A.
ORCID: 0000-0003-3654-7916 (2021) Thiolated and PEGylated silica nanoparticle delivery to hair follicles. International Journal of Pharmaceutics , 593 ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2020.120130
- Khutoryanskiy, V. (2021) Happy 70th birthday, Professor Sarkyt E. Kudaibergenov. Polymers for Advanced Technologies , 32 (7). pp. 2636-2638. ISSN: 1042-7147 | doi: https://dx.doi.org/10.1002/pat.5156
- Kazybayeva, D. , Irmukhametova, G. , Khutoryanskiy, V. (2021) Synthesis of hydrolytically and oxidation‐responsive networks using thiol‐ene “click” chemistry with pentaerythritol tetrakis(3‐mercaptopropionate) and tri/tetra‐acrylates. Polymers for Advanced Technologies , 32 (7). pp. 2682-2689. ISSN: 1042-7147 | doi: https://dx.doi.org/10.1002/pat.5147
- Connon, C. , Cave, R. , Khutoryanskiy, V. , Wright, B. (2020) Transport of cells in hydrogels. | doi: US 10,655,120 B2
- Shah, S. , Williams, A. , Lau, W. , Khutoryanskiy, V. (2020) Planarian toxicity fluorescent assay: a rapid and cheap pre-screening tool for potential skin irritants. Toxicology in Vitro , 69 ISSN: 1879-3177 | doi: https://dx.doi.org/10.1016/j.tiv.2020.105004
- Shan, X. , Williams, A. , Khutoryanskiy, V. (2020) Polymer structure and property effects on solid dispersions with haloperidol: poly(N-vinyl pyrrolidone) and poly(2-oxazolines) studies. International Journal of Pharmaceutics , 590 ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2020.119884
- Porfiryeva, N. , Khutoryanskiy, V. , Moustafine, R. (2020) А study of haloperidol release from polycomplex nanoparticles based on Eudragit® copolymers. Drug development & registration , 9 (3). pp. 45-50. ISSN: 2658-5049 | doi: https://dx.doi.org/10.33380/2305-2066-2020-9-3-45-50
- M. Ways, T. , Ng, K. , Lau, W. , Khutoryanskiy, V. (2020) Silica nanoparticles in transmucosal drug delivery. Pharmaceutics , 12 (8). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics12080751
- Porfiryeva, N. , Moustafine, R. , Khutoryanskiy, V. (2020) PEGylated systems in pharmaceutics. Polymer Science Series C , 61 (1). pp. 62-74. ISSN: 1811-2382 | doi: https://dx.doi.org/10.1134/S181123822001004X
- Bukhovets, A. , Fotaki, N. , Khutoryanskiy, V. , Moustafine, R. (2020) Interpolymer complexes of Eudragit® copolymers as novel carriers for colon-specific drug delivery. Polymers , 12 (7). ISSN: 2073-4360 | doi: https://dx.doi.org/10.3390/polym12071459
- Sevastos, A. , Thomson, N. , Lindsay, C. , Padia, F. , Khutoryanskiy, V. (2020) Rainfastness of agrochemical formulations based on N-vinyl pyrrolidone polymers and their interpolymer complexes with poly(acrylic acid). European Polymer Journal , 134 ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2020.109852
- Albadran, H. , Monteagudo-Mera, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2020) Development of chitosan-coated agar-gelatin particles for probiotic delivery and targeted release in the gastrointestinal tract. Applied Microbiology and Biotechnology , 104 (13). pp. 5749-5757. ISSN: 0175-7598 | doi: https://dx.doi.org/10.1007/s00253-020-10632-w
- Natfji, A. , Nikitin, D. , Semina, I. , Moustafine, R. , Khutoryanskiy, V. , Lin, H. , Stephens, G. , Watson, K. , Osborn, H. , Greco, F. (2020) Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects. Journal of Controlled Release , 322 pp. 227-235. ISSN: 0168-3659 | doi: https://dx.doi.org/10.1016/j.jconrel.2020.02.037
- Abilova, G. , Kaldybekov, D. , Irmukhametova, G. , Kazybayeva, D. , Iskakbayeva, Z. , Kudaibergenov, S. , Khutoryanskiy, V. (2020) Chitosan/Poly(2-ethyl-2-oxazoline) films with ciprofloxacin for application in vaginal drug delivery. Materials , 13 (7). ISSN: 1996-1944 | doi: https://dx.doi.org/10.3390/ma13071709
- Khutoryanskiy, V. (2020) Preparation and publication of chemistry papers in international peer-reviewed journals. Chemical Bulletin of Kazakh National University (1). pp. 40-49. ISSN: 1563-0331 | doi: https://dx.doi.org/10.15328/cb1103
- Irmukhametova, G. , Mun, G. , Khutoryanskiy, V. (2020) Hydrogel dressings. In: Boateng, J. , (eds.) Therapeutic Dressings and Wound Healing Applications. Wiley , New Jersey, USA. pp. 185-207. ISBN: 9781119433262 | doi: https://dx.doi.org/10.1002/9781119433316.ch9
- Agibayeva, L. , Kaldybekov, D. , Porfiryeva, N. , Garipova, V. , Mangazbayeva, R. , Moustafine, R. , Semina, I. , Mun, G. , Kudaibergenov, S. , Khutoryanskiy, V. (2020) Gellan gum and its methacrylated derivatives as in situ gelling mucoadhesive formulations of pilocarpine: In vitro and in vivo studies. International Journal of Pharmaceutics , 577 ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2020.119093
- Kaldybekov, D. , Filippov, S. , Radulescu, A. , Khutoryanskiy, V. (2019) Maleimide-functionalised PLGA-PEG nanoparticles as mucoadhesive carriers for intravesical drug delivery. European Journal of Pharmaceutics and Biopharmaceutics , 143 pp. 24-34. ISSN: 0939-6411 | doi: https://dx.doi.org/10.1016/j.ejpb.2019.08.007
- Brannigan, R. and Khutoryanskiy, V. (2019) Progress and current trends in the synthesis of novel polymers with enhanced mucoadhesive properties. Macromolecular Bioscience , 19 (10). ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.201900194
- Moiseev, R. , Morrison, P. , Steele, F. , Khutoryanskiy, V. (2019) Penetration enhancers in ocular drug delivery. Pharmaceutics , 11 (7). ISSN: 1999-4923 | doi: https://dx.doi.org/10.3390/pharmaceutics11070321
- Kolawole, O. , Lau, W. , Khutoryanskiy, V. (2019) Synthesis and evaluation of boronated chitosan as a mucoadhesive polymer for intravesical drug delivery. Journal of Pharmaceutical Sciences , 108 (9). pp. 3046-3053. ISSN: 0022-3549 | doi: https://dx.doi.org/10.1016/j.xphs.2019.05.006
- Abilova, G. , Kaldybekov, D. , Ozhmukhametova, E. , Saimova, A. , Kazybayeva, D. , Irmukhametova, G. , Khutoryanskiy, V. (2019) Chitosan/poly(2-ethyl-2-oxazoline) films for ocular drug delivery: Formulation, miscibility, in vitro and in vivo studies. European Polymer Journal , 116 pp. 311-320. ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2019.04.016
- Porfiryeva, N. , Nasibullin, S. , Abdullina, S. , Tukhbatullina, I. , Moustafine, R. , Khutoryanskiy, V. (2019) Acrylated Eudragit® E PO as a novel polymeric excipient with enhanced mucoadhesive properties for application in nasal drug delivery. International Journal of Pharmaceutics , 562 pp. 241-248. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2019.03.027
- Chen, H. , Mansfield, E. , Woods, A. , Khutoryanskiy, V. , Forbes, B. , Jones, S. (2019) Mucus penetrating properties of soft, distensible lipid nanocapsules. European Journal of Pharmaceutics and Biopharmaceutics , 139 pp. 76-84. ISSN: 0939-6411 | doi: https://dx.doi.org/10.1016/j.ejpb.2019.02.020
- Kolawole, O. , Lau, W. , Khutoryanskiy, V. (2019) Chitosan/β-glycerophosphate in situ gelling mucoadhesive systems for intravesical delivery of mitomycin-C. International Journal of Pharmaceutics: X , 1 ISSN: 2590-1567 | doi: https://dx.doi.org/10.1016/j.ijpx.2019.100007
- Moustafine, R. , Victorova, A. , Khutoryanskiy, V. (2019) Interpolymer complexes of Carbopol® 971 and poly(2-ethyl-2-oxazoline): physicochemical studies of complexation and formulations for oral drug delivery. International Journal of Pharmaceutics , 558 pp. 53-62. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2019.01.002
- Mirgorodskaya, A. , Kushnazarova, R. , Nikitina, A. , Semina, I. , Nizameev, I. , Kadirov, M. , Khutoryanskiy, V. , Zakharova, L. , Sinyashin, O. (2018) Polyelectrolyte nanocontainers: controlled binding and release of indomethacin. Journal of Molecular Liquids , 272 pp. 982-989. ISSN: 0167-7322 | doi: https://dx.doi.org/10.1016/j.molliq.2018.10.115
- Serres-Gómez, M. , González-Gaitano, G. , Kaldybekov, D. , Mansfield, E. , Khutoryanskiy, V. , Isasi, J. , Dreiss, C. (2018) Supramolecular hybrid structures and gels from host–guest interactions between α-cyclodextrin and PEGylated organosilica nanoparticles. Langmuir , 34 (36). pp. 10591-10602. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/acs.langmuir.8b01744
- Khutoryanskiy, V. , Smyslov, R. , Yakimansky, A. (2018) Modern methods for studying polymer complexes in aqueous and organic solutions. Polymer Science Series A , 60 (5). pp. 553-576. ISSN: 1555-6107 | doi: https://dx.doi.org/10.1134/S0965545X18050085
- Kolawole, O. , Lau, W. , Khutoryanskiy, V. (2018) Methacrylated chitosan as a polymer with enhanced mucoadhesive properties for transmucosal drug delivery. International Journal of Pharmaceutics , 550 (1-2). pp. 123-129. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2018.08.034
- Ways, T. , Lau, W. , Ng, K. , Khutoryanskiy, V. (2018) Synthesis of thiolated, PEGylated and POZylated silica nanoparticles and evaluation of their retention on rat intestinal mucosa in vitro. European Journal of Pharmaceutical Sciences , 122 pp. 230-238. ISSN: 0928-0987 | doi: https://dx.doi.org/10.1016/j.ejps.2018.06.032
- Caló, E. , Ballamy, L. , Khutoryanskiy, V. (2018) Hydrogels in wound management. In: Singh, T. , Laverty, G. , Donnelly, R. , (eds.) Hydrogels: Design, Synthesis and Application in Drug Delivery and Regenerative Medicine. CRC Press , London. ISBN: 9781498748612
- Ozhmukhametova, E. , Mussin, M. , Bayachmetov, A. , Adambosynov, B. , Khutoryanskiy, V. (2018) Experimental purulent corneal ulcer in rabbits as a model to study ocular dosage forms. Kazan Medical Journal , 99 (2). pp. 248-254. ISSN: 2587-9359 | doi: https://dx.doi.org/10.17816/KMJ2018-248
- Al Mahrooqi, J. , Mun, E. , Williams, A. , Khutoryanskiy, V. (2018) Controlling the size of thiolated organosilica nanoparticles. Langmuir , 34 (28). pp. 8347-8354. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/acs.langmuir.8b01556
- Mansfield, E. , Williams, A. , Khutoryanskiy, V. (2018) Applications of temperature-responsive polymers grafted onto solid core nanoparticles. In: Khutoryanskiy, V. and Georgiou, T. , (eds.) Temperature-Responsive Polymers: Chemistry, Properties, and Applications. Wiley and sons pp. 281-299. ISBN: 9781119157786
- Albadran, H. , Chatzifragkou, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2018) Development of surfactant-coated alginate capsules containing Lactobacillus plantarum. Food Hydrocolloids , 82 pp. 490-499. ISSN: 0268-005X | doi: https://dx.doi.org/10.1016/j.foodhyd.2018.04.035
- Ways, T. , Lau, W. , Khutoryanskiy, V. (2018) Chitosan and its derivatives for application in mucoadhesive drug delivery systems. Polymers , 10 (3). ISSN: 2073-4360 | doi: https://dx.doi.org/10.3390/polym10030267
- Ruiz-Rubio, L. , Alonso, M. , Pérez-Álvarez, L. , Alonso, R. , Vilas, J. , Khutoryanskiy, V. (2018) Formulation of carbopol®/Poly(2-ethyl-2-oxazoline)s mucoadhesive tablets for buccal delivery of hydrocortisone. Polymers , 10 (2). ISSN: 2073-4360 | doi: https://dx.doi.org/10.3390/polym10020175
- Mansfield, E. , Pandya, Y. , Mun, E. , Rogers, S. , Abutbul-Ionita, I. , Danino, D. , Williams, A. , Khutoryanskiy, V. (2018) Structure and characterisation of hydroxyethylcellulose–silica nanoparticles. RSC Advances , 8 (12). pp. 6471-6478. ISSN: 2046-2069 | doi: https://dx.doi.org/10.1039/C7RA08716K
-
Cook, S.
,
Methven, L.
,
Parker, J.
ORCID: 0000-0003-4121-5481 , Khutoryanskiy, V. (2018) Polysaccharide food matrices for controlling the release, retention and perception of flavours. Food Hydrocolloids , 79 pp. 253-261. ISSN: 0268-005X | doi: https://dx.doi.org/10.1016/j.foodhyd.2017.12.023
- Kaldybekov, D. , Tonglairoum, P. , Opanasopit, P. , Khutoryanskiy, V. (2018) Mucoadhesive maleimide-functionalised liposomes for drug delivery to urinary bladder. European Journal of Pharmaceutical Sciences , 111 pp. 83-90. ISSN: 0928-0987 | doi: https://dx.doi.org/10.1016/j.ejps.2017.09.039
-
Cook, S.
,
Woods, S.
,
Methven, L.
,
Parker, J.
ORCID: 0000-0003-4121-5481 , Khutoryanskiy, V. (2018) Mucoadhesive polysaccharides modulate sodium retention, release and taste perception. Food Chemistry , 240 pp. 482-489. ISSN: 0308-8146 | doi: https://dx.doi.org/10.1016/j.foodchem.2017.07.134
- Khutoryanskiy, V. (2018) Beyond PEGylation: alternative surface-modification of nanoparticles with mucus-inert biomaterials. Advanced Drug Delivery Reviews , 124 pp. 140-149. ISSN: 0169-409X | doi: https://dx.doi.org/10.1016/j.addr.2017.07.015
- Bepeyeva, A. , de Barros, J. , Albadran, H. , Kakimov, A. , Kakimova, Z. , Charalampopoulos, D. , Khutoryanskiy, V. (2017) Encapsulation of lactobacillus casei into calcium pectinate-chitosan beads for enteric delivery. Journal of Food Science , 82 (12). pp. 2954-2959. ISSN: 0022-1147 | doi: https://dx.doi.org/10.1111/1750-3841.13974
- Kolawole, O. , Lau, W. , Mostafid, H. , Khutoryanskiy, V. (2017) Advances in intravesical drug delivery systems to treat bladder cancer. International Journal of Pharmaceutics , 532 (1). pp. 105-117. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2017.08.120
- Morrison, P. , Porfiryeva, N. , Chahal, S. , Salakhov, I. , Lacourt, C. , Semina, I. , Moustafine, R. , Khutoryanskiy, V. (2017) Crown ethers: novel permeability enhancers for ocular drug delivery?. Molecular Pharmaceutics , 14 (10). pp. 3528-3538. ISSN: 1543-8392 | doi: https://dx.doi.org/10.1021/acs.molpharmaceut.7b00556
- da Silva, J. , Khutoryanskiy, V. , Bruschi, M. , Cook, M. (2017) A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids. International Journal of Pharmaceutics , 528 (1-2). pp. 586-594. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2017.06.025
- Rodríguez, I. , Vázquez, J. , Pastrana, L. , Khutoryanskiy, V. (2017) Enhancement and inhibition effects on the corneal permeability of timolol maleate: polymers, cyclodextrins and chelating agents. International Journal of Pharmaceutics , 529 (1-2). pp. 168-177. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2017.06.075
- Cook, S. , Bull, S. , Methven, L. , Parker, J. , Khutoryanskiy, V. (2017) Mucoadhesion: a food perspective. Food Hydrocolloids , 72 pp. 281-296. ISSN: 0268-005X | doi: https://dx.doi.org/10.1016/j.foodhyd.2017.05.043
- Kandzija, N. and Khutoryanskiy, V. (2017) Delivery of riboflavin-5’-monophosphate into the cornea: can liposomes provide any enhancement effects?. Journal of Pharmaceutical Sciences , 106 (10). pp. 3041-3049. ISSN: 0022-3549 | doi: https://dx.doi.org/10.1016/j.xphs.2017.05.022
- Brannigan, R. and Khutoryanskiy, V. (2017) Synthesis and evaluation of mucoadhesive acryloyl-quaternized PDMAEMA nanogels for ocular drug delivery. Colloids and Surfaces B: Biointerfaces , 155 pp. 538-543. ISSN: 0927-7765 | doi: https://dx.doi.org/10.1016/j.colsurfb.2017.04.050
- Cook, M. , Filippov, S. , Khutoryanskiy, V. (2017) Synthesis and solution properties of a temperature-responsive PNIPAM–b-PDMS–b-PNIPAM triblock copolymer. Colloid and Polymer Science , 295 (8). pp. 1351-1358. ISSN: 1435-1536 | doi: https://dx.doi.org/10.1007/s00396-017-4084-y
- Moustafine, R. , Sitenkov, A. , Bukhovets, A. , Nasibullin, S. , Appeltans, B. , Kabanova, T. , Khutoryanskiy, V. , Guy, V. (2017) Indomethacin-containing interpolyelectrolyte complexes based on Eudragit® E PO/S 100 copolymers as a novel drug delivery system. International Journal of Pharmaceutics , 524 (1-2). pp. 121-133. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2017.03.053
- Hackl, E. , Khutoryanskiy, V. , Ermolina, I. (2017) Hydrogels based on copolymers of 2‐hydroxyethylmethacrylate and 2‐hydroxyethylacrylate as a delivery system for proteins: Interactions with lysozyme. Journal of Applied Polymer Science , 134 (18). ISSN: 0021-8995 | doi: https://dx.doi.org/10.1002/app.44768
- Zainal Abidin, M. , Junqueira-Gonçalves, M. , Khutoryanskiy, V. , Niranjan, K. (2017) Intensifying chitin hydrolysis by adjunct treatments – an overview. Journal of Chemical Technology and Biotechnology , 92 (11). pp. 2787-2798. ISSN: 0268-2575 | doi: https://dx.doi.org/10.1002/jctb.5208
- Bull, S. , Hong, Y. , Khutoryanskiy, V. , Parker, J. , Faka, M. , Methven, L. (2017) Whey protein mouth drying influenced by thermal denaturation. Food Quality and Preference , 56 pp. 233-240. ISSN: 0950-3293 | doi: https://dx.doi.org/10.1016/j.foodqual.2016.03.008 (Part B)
- Ramos, P. , Cerqueira, M. , Cook, M. , Bourbon, A. , Khutoryanskiy, V. , Charalampopoulos, D. , Teixeira, J. , Vicente, A. (2016) Development of an immobilization system for in situ micronutrients release. Food Research International , 90 pp. 121-132. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2016.10.050
- Symonds, B. , Lindsay, C. , Thomson, N. , Khutoryanskiy, V. (2016) Chitosan as a rainfastness adjuvant for agrochemicals. RSC Advances , 6 (104). pp. 102206-102213. ISSN: 2046-2069 | doi: https://dx.doi.org/10.1039/C6RA23485B
- Calo', E. , Barros, J. , Ballamy, L. , Khutoryanskiy, V. (2016) Poly(vinyl alcohol)–Gantrez® AN cryogels for wound care applications. RSC Advances , 6 (107). pp. 105487-105494. ISSN: 2046-2069 | doi: https://dx.doi.org/10.1039/C6RA24573K
- Tonglairoum, P. , Brannigan, R. , Opanasopit, P. , Khutoryanskiy, V. (2016) Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery. Journal of Materials Chemistry B , 4 (40). pp. 6581-6587. ISSN: 0959-9428 | doi: https://dx.doi.org/10.1039/C6TB02124G
- Mun, E. , Williams, A. , Khutoryanskiy, V. (2016) Adhesion of thiolated silica nanoparticles to urinary bladder mucosa: effects of PEGylation, thiol content and particle size. International Journal of Pharmaceutics , 512 (1). pp. 32-38. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2016.08.026
- Mansfield, E. , de la Rosa, V. , Kowalczyk, R. , Grillo, I. , Hoogenboom, R. , Sillence, K. , Hole, P. , Williams, A. , Khutoryanskiy, V. (2016) Side chain variations radically alter the diffusion of poly(2-alkyl-2-oxazoline) functionalised nanoparticles through a mucosal barrier. Biomaterials Science ISSN: 2047-4830 | doi: https://dx.doi.org/10.1039/c6bm00375c
- Calo', E. , de Barros, J. , Fernández-Gutiérrez, M. , San Román, J. , Ballamy, L. , Khutoryanskiy, V. (2016) Antimicrobial hydrogels based on autoclaved poly(vinyl alcohol) and poly(methyl vinyl ether-alt-maleic anhydride) mixtures for wound care applications. RSC Advances , 6 (60). pp. 55211-55219. ISSN: 2046-2069 | doi: https://dx.doi.org/10.1039/C6RA08234C
- Filippov, S. , Bogomolova, A. , Kaberov, L. , Velychkivska, N. , Starovoytova, L. , Cernochova, Z. , Rogers, S. , Lau, W. , Khutoryanskiy, V. , Cook, M. (2016) Internal nanoparticle structure of temperature-responsive self-assembled PNIPAM-b-PEG-b-PNIPAM triblock copolymers in aqueous solutions: NMR, SANS and light scattering studies. Langmuir , 32 (21). pp. 5314-5323. ISSN: 1520-5827 | doi: https://dx.doi.org/10.1021/acs.langmuir.6b00284
- Symonds, B. , Thomson, N. , Lindsay, C. , Khutoryanskiy, V. (2016) Rainfastness of poly(vinyl alcohol) deposits on Vicia faba leaf surfaces: from laboratory-scale washing to simulated rain. ACS Applied Materials and Interfaces , 8 (22). pp. 14220-14230. ISSN: 1944-8244 | doi: https://dx.doi.org/10.1021/acsami.6b01682
-
de Barros, J.
,
Costabile, A.
,
Charalampopoulos, D.
ORCID: 0000-0003-1269-8402 , Khutoryanskiy, V. , Edwards, A. (2016) Evaluating and optimizing oral formulations of live bacterial vaccines using a gastro-small intestine model. European Journal of Pharmaceutics and Biopharmaceutics , 102 pp. 115-122. ISSN: 0939-6411 | doi: https://dx.doi.org/10.1016/j.ejpb.2016.03.010
- Khateb, K. , Ozhmukhametova, E. , Mussin, M. , Seilkhanov, S. , Rakhypbekov, T. , Lau, W. , Khutoryanskiy, V. (2016) In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery. International Journal of Pharmaceutics , 502 (1-2). pp. 70-79. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2016.02.027
- Hongkulsup, C. , Khutoryanskiy, V. , Niranjan, K. (2016) Enzyme assisted extraction of chitin from shrimp shells (Litopenaeus vannamei). Journal of Chemical Technology and Biotechnology , 91 (5). pp. 1250-1256. ISSN: 0268-2575 | doi: https://dx.doi.org/10.1002/jctb.4714
- Smith, S. , Cook, M. , Parker, J. , Methven, L. , Khutoryanskiy, V. (2015) A role for mucoadhesion in flavour enhancement and retention. Flavour Science. Context Products pp. 365-368.
- Khutoryanskiy, V. (2015) Supramolecular materials: longer and safer gastric residence. Nature Materials , 14 (10). pp. 963-964. ISSN: 1476-1122 | doi: https://dx.doi.org/10.1038/nmat4432
- Cook, M. , Smith, S. , Khutoryanskiy, V. (2015) Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing. Chemical Communications , 51 (77). pp. 14447-14450. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/C5CC02428E
- Albadran, H. , Chatzifragkou, A. , Khutoryanskiy, V. , Charalampopoulos, D. (2015) Stability of probiotic Lactobacillus plantarum in dry microcapsules under accelerated storage conditions. Food Research International , 74 pp. 208-216. ISSN: 0963-9969 | doi: https://dx.doi.org/10.1016/j.foodres.2015.05.016
- de Barros, J. , Lechner, T. , Charalampopoulos, D. , Khutoryanskiy, V. , Edwards, A. (2015) Enteric coated spheres produced by extrusion/spheronization provide effective gastric protection and efficient release of live therapeutic bacteria. International Journal of Pharmaceutics , 493 (1-2). pp. 483-494. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2015.06.051
- Mansfield, E. , Sillence, K. , Hole, P. , Williams, A. , Khutoryanskiy, V. (2015) POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers. Nanoscale , 7 (32). pp. 13671-13679. ISSN: 2040-3364 | doi: https://dx.doi.org/10.1039/C5NR03178H
- Cook, M. , Schmidt, S. , Lee, E. , Samprasit, W. , Opanasopit, P. , Khutoryanskiy, V. (2015) Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladder. Journal of Materials Chemistry B , 3 (32). pp. 6599-6604. ISSN: 0959-9428 | doi: https://dx.doi.org/10.1039/C5TB00834D
- Albarkah, Y. , Green, R. , Khutoryanskiy, V. (2015) Probing the mucoadhesive interactions between porcine gastric mucin and some water-soluble polymers. Macromolecular Bioscience , 15 (11). pp. 1546-1553. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.201500158
- Nurpeissova, Z. , Alimkhanova, S. , Mangazbayeva, R. , Shaikhutdinov, Y. , Mun, G. , Khutoryanskiy, V. (2015) Redox- and glucose-responsive hydrogels from poly(vinyl alcohol) and 4-mercaptophenylboronic acid. European Polymer Journal , 69 pp. 132-139. ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2015.06.003
- Hackl, E. , Khutoryanskiy, V. , Tiguman, G. , Ermolina, I. (2015) Evaluation of water properties in HEA–HEMA hydrogels swollen in aqueous-PEG solutions using thermoanalytical techniques. Journal of Thermal Analysis and Calorimetry , 121 (1). pp. 335-345. ISSN: 1588-2926 | doi: https://dx.doi.org/10.1007/s10973-015-4446-y
- Caló, E. and Khutoryanskiy, V. (2015) Biomedical applications of hydrogels: a review of patents and commercial products. European Polymer Journal , 65 pp. 252-267. ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2014.11.024
- Morrison, P. and Khutoryanskiy, V. (2014) Advances in ophthalmic drug delivery. Therapeutic Delivery , 5 (12). pp. 1297-1315. ISSN: 2041-5990 | doi: https://dx.doi.org/10.4155/tde.14.75
- Baygazieva, E. , Yesmurzayeva, N. , Tatykhanova, G. , Mun, G. , Khutoryanskiy, V. , Kudaibergenov, S. (2014) Polymer protected gold nanoparticles: synthesis, characterization and application in catalysis. International Journal of Biology and Chemistry , 7 (1). pp. 14-23.
- Mun, E. , Morrison, P. , Williams, A. , Khutoryanskiy, V. (2014) On the barrier properties of the cornea: a microscopy study of the penetration of fluorescently labeled nanoparticles, polymers, and sodium fluorescein. Molecular Pharmaceutics , 11 (10). pp. 3556-3564. ISSN: 1543-8392 | doi: https://dx.doi.org/10.1021/mp500332m
- Bizley, S. , Williams, A. , Khutoryanskiy, V. (2014) Thermodynamic and kinetic properties of interpolymer complexes assessed by isothermal titration calorimetry and surface plasmon resonance. Soft Matter , 10 pp. 8254-8260. ISSN: 1744-683X | doi: https://dx.doi.org/10.1039/C4SM01138D
- Cook, M. , Charalampopoulos, D. , Khutoryanskiy, V. (2014) Microencapsulation of probiotic bacteria into alginate hydrogels. In: Connon, C. and Hamley, I. , (eds.) Hydrogels in Cell-Based Therapies. RSC soft matter series Royal Society of Chemistry , Cambridge. pp. 95-111. ISBN: 9781782621263
- Morrison, P. and Khutoryanskiy, V. (2014) Enhancement in corneal permeability of riboflavin using calcium sequestering compounds. International Journal of Pharmaceutics , 472 (1-2). pp. 56-64. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2014.06.007
- de Barros, J. , Scherer, T. , Charalampopoulos, D. , Khutoryanskiy, V. , Edwards, A. (2014) A laminated polymer film formulation for enteric delivery of live vaccine and probiotic bacteria. Journal of Pharmaceutical Sciences , 103 (7). pp. 2022-2032. ISSN: 1520-6017 | doi: https://dx.doi.org/10.1002/jps.23997
- Khutoryanskiy, V. , eds. (2014) Mucoadhesive materials and drug delivery systems. Wiley , Chichester. pp 352. ISBN: 9781119941439
- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2014) Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gels. International Journal of Pharmaceutics , 466 (1-2). pp. 400-408. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2014.03.034
- Khutoryanskaya, O. , Morrison, P. , Seilkhanov, S. , Mussin, M. , Ozhmukhametova, E. , Rakhypbekov, T. , Khutoryanskiy, V. (2014) Hydrogen-bonded complexes and blends of poly(acrylic acid) and methylcellulose: nanoparticles and mucoadhesive films for Ocular Delivery of Riboflavin. Macromolecular Bioscience , 14 (2). pp. 225-234. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.201300313
- Mun, E. , Hannell, C. , Rogers, S. , Hole, P. , Williams, A. , Khutoryanskiy, V. (2014) On the role of specific interactions in the diffusion of nanoparticles in aqueous polymer solutions. Langmuir , 30 (1). pp. 308-317. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/la4029035
- Driver, K. , Baco, S. , Khutoryanskiy, V. (2013) Hollow capsules formed in a single stage via interfacial hydrogen-bonded complexation of methylcellulose with poly(acrylic acid) and tannic acid. European Polymer Journal , 49 (12). pp. 4249-4256. ISSN: 0014-3057 | doi: https://dx.doi.org/10.1016/j.eurpolymj.2013.10.004
- Withers, C. , Cook, M. , Methven, L. , Gosney, M. , Khutoryanskiy, V. (2013) Investigation of milk proteins binding to the oral mucosa. Food & Function , 4 (11). pp. 1668-1674. ISSN: 2042-650X | doi: https://dx.doi.org/10.1039/c3fo60291e
- Aravindan, L. , Bicknell, K. , Brooks, G. , Khutoryanskiy, V. , Williams, A. (2013) A comparison of thiolated and disulfide‐crosslinked polyethylenimine for nonviral gene delivery. Macromolecular Bioscience , 13 (9). pp. 1163-1173. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.201300103
- Storha, A. , Mun, E. , Khutoryanskiy, V. (2013) Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery. RSC Advances , 3 (30). pp. 12275-12279. ISSN: 2046-2069 | doi: https://dx.doi.org/10.1039/C3RA42093K
- Morrison, P. , Connon, C. , Khutoryanskiy, V. (2013) Cyclodextrin-mediated enhancement of riboflavin solubility and corneal permeability. Molecular Pharmaceutics , 10 (2). pp. 756-762. ISSN: 1543-8392 | doi: https://dx.doi.org/10.1021/mp3005963
- Cook, M. , Saratoon, T. , Tzortzis, G. , Edwards, A. , Charalampopoulos, D. , Khutoryanskiy, V. (2013) CLSM method for the dynamic observation of pH change within polymer matrices for oral delivery. Biomacromolecules , 14 (2). pp. 387-393. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm301569r
- Cook, M. , Tzortzis, G. , Khutoryanskiy, V. , Charalampopoulos, D. (2013) Layer-by-layer coating of alginate matrices with chitosan–alginate for the improved survival and targeted delivery of probiotic bacteria after oral administration. Journal of Materials Chemistry B , 1 pp. 52-60. | doi: https://dx.doi.org/10.1039/C2TB00126H
- Nualkaekul, S. , Lenton, D. , Cook, M. , Khutoryanskiy, V. , Charalampopoulos, D. (2012) Chitosan coated alginate beads for the survival of microencapsulated Lactobacillus plantarum in pomegranate juice. Carbohydrate Polymers , 90 (3). pp. 1281-1287. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2012.06.073
- Sogias, I. , Williams, A. , Khutoryanskiy, V. (2012) Chitosan-based mucoadhesive tablets for oral delivery of ibuprofen. International Journal of Pharmaceutics , 436 (1-2). pp. 602-610. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2012.07.007
- Kudaibergenov, S. , Nuraje, N. , Khutoryanskiy, V. (2012) Amphoteric nano-, micro-, and macrogels, membranes, and thin films. Soft Matter , 8 (36). pp. 9302-9321. ISSN: 1744-683X | doi: https://dx.doi.org/10.1039/C2SM25766A
- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2012) Microencapsulation of probiotics for gastrointestinal delivery. Journal of Controlled Release , 162 (1). pp. 56-67. ISSN: 0168-3659 | doi: https://dx.doi.org/10.1016/j.jconrel.2012.06.003
- Bizley, S. , Williams, A. , Kemp, F. , Khutoryanskiy, V. (2012) Optimizing layer-by-layer deposition of interpolymer complexes on solid substrates using Biacore. Soft Matter , 8 (25). pp. 6782-6787. ISSN: 1744-683X | doi: https://dx.doi.org/10.1039/C2SM25652E
- Cave, R. , Cook, J. , Connon, C. , Khutoryanskiy, V. (2012) A flow system for the on-line quantitative measurement of the retention of dosage forms on biological surfaces using spectroscopy and image analysis. International Journal of Pharmaceutics , 428 (1-2). pp. 96-102. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2012.02.047
- Cook, J. , Goodall, G. , Khutoryanskaya, O. , Khutoryanskiy, V. (2012) Microwave-assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions . Macromolecular Rapid Communications , 33 (4). pp. 332-336. ISSN: 1022-1336 | doi: https://dx.doi.org/10.1002/marc.201100742
- Wright, B. , Cave, R. , Cook, J. , Khutoryanskiy, V. , Mi, S. , Chen, B. , Leyland, M. , Connon, C. (2012) Enhanced viability of corneal epithelial cells for efficient transport/storage using a structurally-modified calcium alginate hydrogel. Regenerative Medicine , 7 (3). pp. 295-307. ISSN: 1746-076X | doi: https://dx.doi.org/10.2217/rme.12.7
- Irmukhametova, G. , Fraser, B. , Keddie, J. , Mun, G. , Khutoryanskiy, V. (2012) Hydrogen-bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surfaces . Langmuir , 28 (1). pp. 299-306. ISSN: 0743-7463 | doi: https://dx.doi.org/10.1021/la2038735
- Hall, D. , Khutoryanskaya, O. , Khutoryanskiy, V. (2011) Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems. Soft Matter , 7 (20). pp. 9620-9623. ISSN: 1744-683X | doi: https://dx.doi.org/10.1039/C1SM05929G
- Irmukhametova, G. , Mun, G. , Khutoryanskiy, V. (2011) Thiolated mucoadhesive and PEGylated nonmucoadhesive organosilica nanoparticles from 3-Mercaptopropyltrimethoxysilane . Langmuir , 27 (15). pp. 9551-9556. ISSN: 1520-5827 | doi: https://dx.doi.org/10.1021/la201385h
- Cook, M. , Tzortzis, G. , Charalampopoulos, D. , Khutoryanskiy, V. (2011) Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteria. Biomacromolecules , 12 (7). pp. 2834-2840. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm200576h
- Khutoryanskiy, V. (2011) Advances in mucoadhesion and mucoadhesive polymers. Macromolecular Bioscience , 11 (6). pp. 748-764. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.201000388
- Mi, S. , Khutoryanskiy, V. , Jones, R. , Zhu, X. , Hamley, I. , Connon, C. (2011) Photochemical cross-linking of plastically compressed collagen gel produces an optimal scaffold for corneal tissue engineering. Journal of Biomedical Materials Research Part A , 99A (1). pp. 1-8. ISSN: 1549-3296 | doi: https://dx.doi.org/10.1002/jbm.a.33152
- Khutoryanskiy, V. (2011) Application of interpolymer complexation to coat solid and soft surfaces. pp. 212-218.
- Zhunuspayev, D. , Mun, G. , Khutoryanskiy, V. (2010) Temperature-responsive properties and drug solubilization capacity of amphiphilic copolymers based on N-vinylpyrrolidone and vinyl propyl ether. Langmuir , 26 (10). pp. 7590-7597. ISSN: 1520-5827 | doi: https://dx.doi.org/10.1021/la904403k
- Sogias, I. , Khutoryanskiy, V. , Williams, A. (2010) Exploring the Factors Affecting the Solubility of Chitosan in Water. Macromolecular Chemistry and Physics , 211 (4). pp. 426-433. ISSN: 1022-1352 | doi: https://dx.doi.org/10.1002/macp.200900385
- Khutoryanskaya, O. , Potgieter, M. , Khutoryanskiy, V. (2010) Multilayered hydrogel coatings covalently-linked to glass surfaces showing a potential to mimic mucosal tissues . Soft Matter , 6 pp. 551-556. ISSN: 1744-683X | doi: DOI:10.1039/b918007a
- Khutoryanskiy, . (2009) Pharmaceutical applications of interpolymer complexes. In: Khutoryanskiy, . and Staikos, . , (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications . World Scientific , Singapore. pp. 235-258. ISBN: 9789812707857
- Khutoryanskiy, . , Dubolazov, . , Mun, . (2009) pH- and ionic strength effects on interpolymer complexation via hydrogen-bonding. In: Khutoryanskiy, . and Staikos, . , (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications . World Scientific , Singapore. pp. 1-22. ISBN: 9789812707857
- Khutoryanskiy, V. and Khutoryanskaya, O. (2009) A basic guide to hydrogels. Newsletter of the United Kingdom and Ireland Controlled Release Society , 14 pp. 26-30.
- Aravindan, L. , Bicknell, K. , Brooks, G. , Khutoryanskiy, V. , Williams, A. (2009) Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine . International Journal of Pharmaceutics , 378 (1-2). pp. 201-210. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2009.05.052
- Khutoryanskiy, V. and Khutoryanskaya, O. (2009) Design and evaluation of hydrogel films based on polymeric blends. In: Stein, D. , (eds.) Handbook of Hydrogels: Properties, Preparation and Applications . Chemical Engineering Methods and Technology Nova Science Publishers, Inc. , Hauppauge NY USA. pp. 521-540. ISBN: 9781607417026
- Al-Saadi , A. , Yu , C. , Khutoryanskiy, V. , Shih , S. , Crossley , A. , Tsang , S. (2009) Layer-by-layer electrostatic entrapment of protein molecules on superparamagnetic nanoparticle: new strategy to enhance adsorption capacity and maintain biological activity. Journal of Physical Chemistry C , 113 (34). pp. 15260-15265. ISSN: 1932-7447 | doi: DOI:10.1021/jp903100j
- Luo, . , Yin, . , Khutoryanskaya, . , Khutoryanskiy, . (2008) Mucoadhesive and elastic films based on blends of chitosan and hydroxyethylcellulose. Macromolecular Bioscience , 8 (2). pp. 184-192. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.200700185
- Sogias, I. , Williams, A. , Khutoryanskiy, V. (2008) Why is Chitosan Mucoadhesive? . Biomacromolecules , 9 (7). pp. 1837-1842. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm800276d
- Zhunuspayev, D. , Mun, G. , Hole, P. , Khutoryanskiy, V. (2008) Solvent Effects on the Formation of Nanoparticles and Multilayered Coatings Based on Hydrogen-Bonded Interpolymer Complexes of Poly(acrylic acid) with Homo- and Copolymers of N-Vinyl Pyrrolidone. Langmuir , 24 (23). pp. 13742-13747. ISSN: 0743-7463 | doi: DOI:10.1021/la802852h
- Khutoryanskaya, O. , Mayeva, Z. , Mun, G. , Khutoryanskiy, V. (2008) Designing Temperature-Responsive Biocompatible Copolymers and Hydrogels Based on 2-Hydroxyethyl(meth)acrylates. Biomacromolecules , 9 (12). pp. 3353-3361. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm8006242
- Aal, . , Khutoryanskiy, . , Nurkeeva, . , Mun, . (2007) Optimization of electroless copper plating on polyethylene films modified by surface grafting of vinyl ether of monoethanolamine. Eurasian Chemico-Technological Journal , 9 (1). pp. 63-70. ISSN: 1562-3920
- Fefelova, . , Nurkeeva, . , Mun, . , Khutoryanskiy, . (2007) Mucoadhesive interactions of amphiphilic cationic copolymers based on [2-(methacryloyloxy)ethyl]trimethylammonium chloride. International Journal of Pharmaceutics , 339 (1-2). pp. 25-32. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2007.02.019
- Khutoryanskaya, . , Williams, . , Khutoryanskiy, . (2007) pH-mediated interactions between poly(acrylic acid) and methylcellulose in the formation of ultrathin multilayered hydrogels and spherical nanoparticles. Macromolecules , 40 (21). pp. 7707-7713. ISSN: 0024-9297 | doi: https://dx.doi.org/10.1021/ma071644v
- Khutoryanskiy, . (2007) Hydrogen-bonded interpolymer complexes as materials for pharmaceutical applications. International Journal of Pharmaceutics , 334 (1-2). pp. 15-26. ISSN: 0378-5173 | doi: https://dx.doi.org/10.1016/j.ijpharm.2007.01.037
- Mun, . , Nurkeeva, . , Beissegul, . , Dubolazov, . , Urkimbaeva, . , Park, . , Khutoryanskiy, . (2007) Temperature-responsive water-soluble copolymers based on 2-hydroxyethyl acrylate and butyl acrylate. Macromolecular Chemistry and Physics , 208 (9). pp. 979-987. ISSN: 1022-1352 | doi: https://dx.doi.org/10.1002/macp.200600555
- Khutoryanskiy, . and Tirelli, . (2007) Oxidation-responsiveness of nanomaterials for targeting inflammatory reactions. Pure and Applied Chemistry , 80 (8). pp. 1703-1718. ISSN: 0033-4545 | doi: https://dx.doi.org/10.1351/pac200880081703
- Dubolazov, . , Nurkeeva, . , Mun, . , Khutoryanskiy, . (2006) Design of mucoadhesive polymeric films based on blends of poly(acrylic acid) and (hydroxypropyl)cellulose. Biomacromolecules , 7 (5). pp. 1637-1643. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm060090l
- Mangazbaeva, . , Mun, . , Nurkeeva, . , Khutoryanskiy, . (2006) Interpolymer complexes of hydroxy-propylmethylcellulose with polycarboxylic acids in aqueous solutions. Polymer International , 55 (6). pp. 668-674. ISSN: 0959-8103 | doi: https://dx.doi.org/10.1002/pi.2012
- Mun, . , Nurkeeva, . , Akhmetkalieva, . , Shmakov, . , Khutoryanskiy, . , Lee, . , Park, . (2006) Novel temperature-responsive water-soluble copolymers based on 2-hydroxyethylacrylate and vinyl butyl ether and their interactions with poly(carboxylic acids). Journal of Polymer Science Part B-Polymer Physics , 44 (1). pp. 195-204. ISSN: 0887-6266 | doi: https://dx.doi.org/10.1002/polb.20695
- Nurkeeva, . , Mun, . , Sergaziev, . , Fefelova, . , Sarsenbaeva, . , Khutoryanskiy, . (2006) Synthesis of cationic water-soluble copolymers and hydrogels based on [2-(methacryloyloxy)ethyl]trimethylammonium cloride and 2-hydroxyethylacrylate and their complex formation with poly(acrylic acid). Journal of Polymer Science Part B-Polymer Physics , 44 (5). pp. 845-853. ISSN: 0887-6266 | doi: https://dx.doi.org/10.1002/polb.20742
- Qu, . , Khutoryanskiy, . , Stewart, . , Rahman, . , Papahadjopoulos-Sternberg, . , Dufes, . , McCarthy, . , Wilson, . , Lyons, . , Carter, . , Schatzlein, . , Uchegbu, . (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules , 7 (12). pp. 3452-3459. ISSN: 1525-7797 | doi: https://dx.doi.org/10.1021/bm0604000
- Yin, . , Luo, . , Chen, . , Khutoryanskiy, . (2006) Miscibility studies of the blends of chitosan with some cellulose ethers. Carbohydrate Polymers , 63 (2). pp. 238-244. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2005.08.041
- Khutoryanskaya, . , Khutoryanskiy, . , Pethrick, . (2005) Characterisation of blends based on hydroxyethylcellulose and maleic acid-alt-methyl vinyl ether. Macromolecular Chemistry and Physics , 206 (15). pp. 1497-1510. ISSN: 1022-1352 | doi: https://dx.doi.org/10.1002/macp.200500069
- Nurkeeva, . , Mun, . , Dubolazov, . , Khutoryanskiy, . (2005) pH effects on the complexation, miscibility and radiation-induced crosslinking in poly(acrylic acid)-poly (vinyl alcohol) blends. Macromolecular Bioscience , 5 (5). pp. 424-432. ISSN: 1616-5187 | doi: https://dx.doi.org/10.1002/mabi.200400200
- Nurkeeva, . , Tyukova, . , Suvorova, . , Mun, . , Dzhusupbekova, . , Khutoryanskiy, . (2005) Miscibility studies in poly(methyl vinyl ether)/hydroxypropylcellulose binary system in aqueous solutions and solid state. Carbohydrate Polymers , 62 (1). pp. 80-86. ISSN: 0144-8617 | doi: https://dx.doi.org/10.1016/j.carbpol.2005.06.023