Professor Laurence Harwood

Email:
l.m.harwood@reading.ac.uk
Phone:
+44 (0) 118 378 7417
Job title:
Professor

Responsibilities:

Professor of Organic Chemistry
Director of the Chemical Analysis Facility.

Office

209

Building location

Chemistry

Areas of interest

Work in the Biomedical, Molecular and Analytical Chemistry research group revolves around the development of new synthetic methods and their application to the synthesis of natural and unnatural products. There are projects underway with the aims of developing synthetic approaches towards amino acids and peptides with an increasing emphasis on chemistry at the biological interface. This work has led to a spin out company called TechnoPep.

The group also has interests in the materials area, working closely with academic institutes and industrial centres throughout Europe in the area of nuclear reprocessing, developing ligands that selectively remove the minor actinides to reduce the long term nuclear legacy of stored waste. This work is also being applied to soil remediation for removal of radionucleides and heavy metals.

The group has an EU grant worth €225,000 in the SACSESS Framework to prepare selective ligands from actinide extraction in the presence of lanthanide.

Read more about Professor Harwood's research interests

Learn about Professor Harwood's professional activities

Research centres and groups

Professor Harwood is part of the Biomedical, Molecular and Analytical Chemistry research group.

Learn more about our research groups

Publications

Pitt, P. ORCID: 0000-0003-2842-7607 and Harwood, L. ORCID: 0000-0002-8442-7380 (2021) Kinetics of the parallel-consecutive bimolecular reaction: a solution to the inverse problem involving the Lambert-W function.. Physical Chemistry Chemical Physics , 23 (42). pp. 24102-24105. ISSN: 1463-9076 | doi: https://dx.doi.org/10.1039/d1cp03611d
Monir, D. ORCID: 0000-0001-9511-063X and Harwood, L. ORCID: 0000-0002-8442-7380 (2021) A mild approach to synthesise enantiopure glycine-derived 5-phenylthiomorpholinone. Tetrahedron , 84 ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2021.132035

Gwon, Y. , Lee, J. , Lee, K. , Ogden, M. , Harwood, L. , Lee, T. (2020) Prussian blue decoration on polyacrylonitrile nanofibers using polydopamine for effective Cs ion removal. Industrial & Engineering Chemistry Research , 59 (11). pp. 4872-4880. ISSN: 0888-5885 | doi: https://dx.doi.org/10.1021/acs.iecr.9b06639
Canner, A. , Harwood, L. , Cowell, J. , Babra, J. , Brown, S. , Ogden, M. (2020) Spectrophotometric analysis of ternary uranyl systems to replace tri-N-butyl phosphate (TBP) in used fuel reprocessing. Journal of Solution Chemistry , 49 (1). pp. 52-67. ISSN: 0095-9782 | doi: https://dx.doi.org/10.1007/s10953-019-00942-7
Distler, P. , Mindová, M. , John, J. , Babain, V. , Alyapyshev, M. , Tkachenko, L. , Kenf, E. , Harwood, L. , Afsar, A. (2020) Fluorinated carbonates as new diluents for extraction and separation of f-block elements. Solvent Extraction and Ion Exchange , 38 (2). pp. 180-193. ISSN: 1532-2262 | doi: https://dx.doi.org/10.1080/07366299.2019.1708004
Amphlett, J. , Pepper, S. , Riley, A. , Harwood, L. , Cowell, J. , Whittle, K. , Lee, T. , Ogden, M. (2020) Impact of copper(II) on activation product removal from reactor decommissioning effluents in South Korea. Journal of Industrial and Engineering Chemistry , 82 pp. 261-268. ISSN: 1226086X | doi: https://dx.doi.org/10.1016/j.jiec.2019.10.022
Distler, P. , Stamberg, K. , John, J. , Harwood, L. , Lewis, F. (2020) Thermodynamic parameters of Am(III), Cm(III) and Eu(III) extraction by CyMe4-BTPhen in cyclohexanone from HNO3 solutions. Journal of Chemical Thermodynamics , 141 ISSN: 0021-9614 | doi: https://dx.doi.org/10.1016/j.jct.2019.105955
Afsar, A. , Babra, J. , Distler, P. , Harwood, L. , Hopkins, I. , John, J. , Westwood, J. , Selfe, Z. (2020) Extraction properties of 4-Tetra(hydroxyphenyl)BTPhen in liquid-liquid extraction systems with Cyclohexanone/Octanol or in a solid-phase extraction system. Heterocycles , 101 (1). pp. 209-222. ISSN: 1881-0942 | doi: https://dx.doi.org/10.3987/COM-19-S(F)14

Harwood, L. , Pitt, P. , Scott, J. , Sousa, D. (2019) Ultra-high pressure direct syntheses of bis(imidazolium-3-yl)alkane dichlorides. Tetrahedron , 75 (44). ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2019.130639
Jang, G. , Cho, E. , Harwood, L. , Lee, T. (2019) Turn-on detection of Cs Ions based on conjugated polymer-graphene oxide. Polymer(Korea) , 43 (2). pp. 302-308. ISSN: 2234-8077 | doi: https://dx.doi.org/10.7317/pk.2019.43.2.302
Jang, J. , Harwood, L. , Lee, D. (2019) 5-Bromo-2,9-bis(5,6-diphenyl-1,2,4-triazin-3-yl)-1,10-phenanthrolin as an efficient ligand for selective removal of strontium and cobalt from aqueous solution. Bulletin of the Korean Chemical Society , 40 (5). pp. 424-428. ISSN: 1229-5949 | doi: https://dx.doi.org/10.1002/bkcs.11706
Afsar, A. , Distler, P. , Harwood, L. , John, J. , Babra, J. , Selfe, Z. , Cowell, J. , Westwood, J. (2019) Separation of minor actinides from lanthanides using immobilized ligand systems: the role of the counterion. Heterocycles , 99 (2). pp. 825-833. ISSN: 1881-0942 | doi: https://dx.doi.org/10.3987/COM-18-S(F)71

Namgung, H. , Gwon, Y. , Kim, J. , Jang, G. , Pepper, S. , Ogden, M. , Whittle, K. , Harwood, L. , Lee, T. (2018) Synthesis of Prussian blue-embedded porous polymer for detection and removal of Cs ions. Polymer , 158 pp. 320-326. ISSN: 0032-3861 | doi: https://dx.doi.org/10.1016/j.polymer.2018.11.001
Afsar, A. , Westwood, J. , Distler, P. , Harwood, L. , Mohan, S. , John, J. , Davis, F. (2018) Separation of Am(III) from Cm(III) and Eu(III) by electro-spun polystyrene- immobilized CyMe4-BTPhen. Tetrahedron , 74 (38). pp. 5258-5262. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2018.04.037
Reilly, S. , Su, J. , Keith, J. , Yang, P. , Batista, E. , Gaunt, A. , Harwood, L. , Hudson, M. , Lewis, F. , Scott, B. , Sharrad, C. , Whittaker, D. (2018) Plutonium coordination and redox chemistry with the CyMe4-BTPhen polydentate N-donor extractant ligand. Chemical Communications , 54 (89). pp. 12582-12585. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c8cc06015k
Hughes, D. , Afsar, A. , Laventine, D. , Shaw, E. , Harwood, L. , Hodson, M. (2018) Metal removal from soil leachates using DTPA-functionalised maghemite nanoparticles, a potential soil washing technology. Chemosphere , 209 pp. 480-488. ISSN: 1879-1298 | doi: https://dx.doi.org/10.1016/j.chemosphere.2018.06.121
Westwood, J. , Harwood, L. , Afsar, A. , Cowell, J. , Distler, P. , John, J. (2018) Synthesis and screening of a novel (dppz)-BTPhen ligand for separation of Americium from Europium. Letters in Organic Chemistry , 15 (5). pp. 340-344. ISSN: 1570-1786 | doi: https://dx.doi.org/10.2174/1570178615666171220144058
Pepper, S. , Whittle, K. , Harwood, L. , Cowell, J. , Lee, T. , Ogden, M. (2018) Cobalt and nickel uptake by silica-based extractants. Separation Science and Technology , 53 (10). pp. 1552-1562. ISSN: 0149-6395 | doi: https://dx.doi.org/10.1080/01496395.2017.1405034
Lewis, F. , Harwood, L. , Hudson, M. , Afsar, A. , Laventine, D. , John, J. , Stastna, K. , Distler, P. (2018) Separation of the minor actinides americium(III) and curium(III) by hydrophobic and hydrophilic BTPhen ligands: exploiting differences in their rates of extraction and effective separations at equilibrium. Solvent Extraction and Ion Exchange , 36 (2). pp. 115-135. ISSN: 0736-6299 | doi: https://dx.doi.org/10.1080/07366299.2018.1429358
Distler, P. , Stamberg, K. , John, J. , Harwood, L. , Lewis, F. (2018) Modelling of the Am(III) - Cm(III) kinetic separation effect observed during metal ion extraction by bis-(1,2,4)-triazine ligands. Separation Science and Technology , 53 (2). pp. 277-285. ISSN: 0149-6395 | doi: https://dx.doi.org/10.1080/01496395.2017.1384017

Uroos, M. , Pitt, P. , Harwood, L. , Lewis, W. , Blake, A. , Hayes, C. (2017) Total synthesis of (–)-aritasone via the ultra-high pressure hetero-Diels Alder dimerization of (-)-pinocarvone. Organic and Biomolecular Chemistry , 15 (40). pp. 8523-8528. ISSN: 1477-0520 | doi: https://dx.doi.org/10.1039/c7ob02204b
Cranwell, P. , Harwood, L. , Moody, C. (2017) Experimental organic chemistry. Wiley-Blackwell pp 688. ISBN: 9781119952398
Edwards, A. , Geist, A. , Müllich, U. , Sharrad, C. , Pritchard, R. , Whitehead, R. , Harwood, L. (2017) Transition metal-free, visible-light mediated synthesis of 1,10-phenanthroline derived ligand systems. Chemical Communications , 53 (58). pp. 8160-8163. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c7cc03903d
Afsar, A. , Cowell, J. , Distler, P. , Harwood, L. , John, J. , Westwood, J. (2017) Synthesis of novel BTPhen-functionalized silica-coated magnetic nanoparticles for separating trivalent actinides and lanthanides. Synlett , 28 (20). pp. 2795-2799. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-0036-1590865
Hughes, D. , Asfar, A. , Harwood, L. , Jiang, T. , Laventine, D. , Shaw, L. , Hodson, M. (2017) Adsorption of Pb and Zn from binary metal solutions and in the presence of dissolved organic carbon by DTPA-functionalised, silica-coated magnetic nanoparticles. Chemosphere , 183 pp. 519-527. ISSN: 0045-6535 | doi: https://dx.doi.org/10.1016/j.chemosphere.2017.05.146
Edwards, A. , Mocilac, P. , Geist, A. , Harwood, L. , Sharrad, C. , Burton, N. , Whitehead, R. , Denecke, M. (2017) Hydrophilic 2,9-bis-triazolyl-1,10-phenanthroline ligands enable selective Am(iii) separation: a step further towards sustainable nuclear energy. Chemical Communications , 53 (36). pp. 5001-5004. ISSN: 1364-548X | doi: https://dx.doi.org/10.1039/c7cc01855j
Afsar, A. , Distler, P. , Harwood, L. , John, J. , Westwood, J. (2017) Extraction of minor actinides, lanthanides and other fission products by silica-immobilized BTBP/BTPhen ligands. Chemical Communications , 53 (28). pp. 4010-4013. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c7cc01286a
Afsar, A. , Edwards, A. , Geist, A. , Harwood, L. , Hudson, M. , Westwood, J. , Whitehead, R. (2017) Effective separation of Am(III) from Cm(III) using modified btphen ligands. Heterocycles , 95 (1). pp. 575-586. ISSN: 1881-0942 | doi: https://dx.doi.org/10.3987/COM-16-S(S)26

Afsar, A. , Distler, P. , Harwood, L. , John, J. , Westwood, J. (2016) Synthesis and screening of modified 6,6′-Bis(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrobenzo[e][1,2,4]triazin-3-yl)-2,2′-bipyridine ligands for actinide and lanthanide separation in nuclear waste treatment. Journal of Organic Chemistry ISSN: 0022-3263 | doi: https://dx.doi.org/10.1021/acs.joc.6b01264
Edwards, A. , Wagner, C. , Geist, A. , Burton, N. , Sharrad, C. , Adams, R. , Pritchard, R. , Panak, P. , Whitehead, R. , Harwood, L. (2016) Exploring electronic effects on the partitioning of actinides(III) from lanthanides(III) using functionalised bis-triazinyl phenanthroline ligands. Dalton Transactions (45). pp. 18102-18112. ISSN: 1364-5447 | doi: https://dx.doi.org/10.1039/C6DT02474B
Durán-Peña, M. , Flores-Giubi, M. , Botubol-Ares, J. , Harwood, L. , Collado, I. , Macías-Sánchez, A. , Hernández-Galán, R. (2016) Chemoselective and stereoselective lithium carbenoid mediated cyclopropanation of acyclic allylic alcohols. Organic and Biomolecular Chemistry , 14 (9). pp. 2731-2741. ISSN: 1477-0520 | doi: https://dx.doi.org/10.1039/C5OB02617B
Lewis, F. , Harwood, L. , Hudson, M. , Núñez, A. , Galán, H. , Espartero, A. (2016) Synthesis and evaluation of a novel hydrophilic 6,6′-bis(1,2,4-triazin-3-yl)-2,2′-bipyridine ligand for separating actinide(III) from lanthanide(III). Synlett , 27 (1). pp. 1-5. ISSN: 1437-2096 | doi: https://dx.doi.org/10.1055/s-0035-1560541
Nouga, A. , Ndom, J. , Mpondo, E. , Nyobe, J. , Njoya, A. , Meva’a, L. , Cranwell, P. , Howell, J. , Harwood, L. , Wansi, J. (2016) New furoquinoline alkaloid and flavanone glycoside derivatives from the leaves of Oricia suaveolens and Oricia renieri (Rutaceae). Natural Product Research , 30 (3). pp. 305-310. ISSN: 1478-6419 | doi: https://dx.doi.org/10.1080/14786419.2015.1057727

Botubol-Ares, J. , Durán-Pena, M. , Hernández-Galán, R. , Collado, I. , Harwood, L. , Macías-Sánchez, A. (2015) Diastereoselective and enantioselective preparation of nor-mevaldic acid surrogates through desymmetrisation methodology. Enantioselective synthesis of (+) and (-) nor-mevalonic lactones. Tetrahedron , 71 (40). pp. 7531-7538. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2015.08.010
Higginson, M. , Thompson, P. , Marsden, O. , Livens, F. , Harwood, L. , Lewis, F. , Hudson, M. , Heath, S. (2015) Rapid selective separation of americium/curium from simulated nuclear forensic matrices using triazine ligands. Radiochimica Acta , 103 (10). ISSN: 0033-8230 | doi: https://dx.doi.org/10.1515/ract-2015-2403
Zeng, Q. , Lewis, F. , Harwood, L. , Hartl, F. (2015) Role of ligands in catalytic water oxidation by mononuclear ruthenium complexes. Coordination Chemistry Reviews , 304-305 pp. 88-101. ISSN: 0010-8545 | doi: https://dx.doi.org/10.1016/j.ccr.2015.03.003
Lewis, F. , Harwood, L. , Hudson, M. , Geist, A. , Kozhevnikov, V. , Distler, P. , John, J. (2015) Hydrophilic sulfonated bis-1,2,4-triazine ligands are highly effective reagents for separating actinides(iii) from lanthanides(iii) via selective formation of aqueous actinide complexes. Chemical Science , 6 (8). pp. 4812-4821. ISSN: 1478-6524 | doi: https://dx.doi.org/10.1039/C5SC01328C
Lewis, F. , Harwood, L. , Hudson, M. , Müllich, U. , Geist, A. (2015) Efficient masking of corrosion and fission products such as Ni(II) and Pd(II) in the presence of the minor actinide Am(III) using hydrophilic anionic or cationic bis-triazines. Chemical Communications , 51 (44). pp. 9189-9192. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c5cc02336j
Botubol-Ares, J. , Durán-Peña, M. , Hernández-Galán, R. , Collado, I. , Harwood, L. , Macías-Sánchez, A. (2015) nor-Mevaldic acid surrogates as selective antifungal agent leads against Botrytis cinerea. Enantioselective preparation of 4-hydroxy-6-(1-phenylethoxy)tetrahydro-2H-pyran-2-one. Bioorganic & Medicinal Chemistry , 23 (13). pp. 3379-3387. ISSN: 0968-0896 | doi: https://dx.doi.org/10.1016/j.bmc.2015.04.048
Afsar, A. , Harwood, L. , Hudson, M. , Westwood, J. , Geist, A. (2015) Effective separation of the actinides Am(III) and Cm(III) by electronic modulation of bis-(1,2,4-triazin-3-yl)phenanthrolines. Chemical Communications , 51 (27). pp. 5860-5863. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c5cc00567a

Afsar, A. , Harwood, L. , Hudson, M. , Distler, P. , John, J. (2014) Effective separation of Am(III) and Eu(III) from HNO3 solutions using CyMe4-BTPhen-functionalized silica-coated magnetic nanoparticles. Chemical Communications , 50 (95). pp. 15082-15085. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c4cc07478e
Afsar, A. , Westwood, J. , Harwood, L. , Hudson, M. , Laventine, D. , Geist, A. (2014) The effect of alkyl substitution on the extraction properties of BTPhen ligands for the partitioning of trivalent minor actinides and lanthanides in spent nuclear fuels. Jordan Journal of Chemistry , 9 (1). pp. 50-58.
Afsar, A. , Harwood, L. , Hudson, M. , Distler, P. , John, J. (2014) Effective separation of Am(III) and Eu(III) from HNO3 Q1 Q2 solutions using CyMe4-BTPhen-functionalized silica-coated magnetic nanoparticles. Chemical Communications , 50 pp. 15082-15085. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c4cc07478e
Afsar, A. , Harwood, L. , Hudson, M. , Hodson, M. , Shaw, E. (2014) Neocuproine-functionalized silica-coated magnetic nanoparticles for extraction of copper(II) from aqueous solution. Chemical Communications , 50 (56). pp. 7477-7480. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c4cc01250j

Treus, M. , Harwood, L. , Estevez, J. , Salas, C. , Drew, M. , Estevez, R. (2013) Intramolecular Diels-Alder furan-mediated synthesis of 8-aryl-3, 4-di-hydroisoquinolin-1(2H)-ones, convenient precursors of indeno[1,2,3-ij]isoquinolines. Synlett , 24 (17). pp. 2221-2224. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-0033-1339693
Afsar, A. , Laventine, D. , Harwood, L. , Hudson, M. , Geist, A. (2013) Utilizing electronic effects in the modulation of BTPhen ligands with respect to the partitioning of minor actinides from lanthanides. Chemical Communications , 49 (76). pp. 8534-8536. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/c3cc45126g
Afsar, A. , Laventine, D. , Harwood, L. , Hudson, M. , Geist, A. (2013) Immobilisation of phenanthroline-bis triazine(c1-btphen) on magnetic nanoparticles for co-extraction of americium(III) and europium(III). Heterocycles , 88 (1). pp. 613-620. ISSN: 1881-0942 | doi: https://dx.doi.org/10.3987/COM-13-S(S)9
Lewis, F. , Harwood, L. , Hudson, M. , Drew, M. , Hubscher-Bruder, V. , Videva, V. , Arnaud-Neu, F. , Stamberg, K. , Vyas, S. (2013) BTBPs versus BTPhens: some reasons for their differences in properties concerning the partitioning of minor actinides and the advantages of BTPhens. Inorganic Chemistry , 52 (9). pp. 4993-5005. ISSN: 0020-1669 | doi: https://dx.doi.org/10.1021/ic3026842
Whittaker, D. , Griffiths, T. , Helliwell, M. , Swinburne, A. , Natrajan, L. , Lewis, F. , Harwood, L. , Parry, S. , Sharrad, C. (2013) Lanthanide speciation in potential SANEX and GANEX actinide/ 2 lanthanide separations using Tetra-N-Donor extractants. Inorganic Chemistry , 52 (7). pp. 3429-3444. ISSN: 0020-1669 | doi: https://dx.doi.org/10.1021/ic301599y
Hudson, M. , Harwood, L. , Laventine, D. , Lewis, F. (2013) Use of soft heterocyclic N‑donor ligands to separate actinides and lanthanides. Inorganic Chemistry , 52 (7). pp. 3414-3428. ISSN: 0020-1669 | doi: https://dx.doi.org/10.1021/ic3008848

Harwood, L. and Yan, R. (2012) Asymmetric synthesis of peptides. | doi: US 2012/0190816 A9
Harwood, L. , Wellings, D. , Moody, D. (2012) Chemical ligation by ring opening of oxo-thiomorpholines. | doi: WO2012/020231
Lewis, F. , Harwood, L. , Hudson, M. , Drew, M. , Wilden, A. , Sypula, M. , Modolo, G. , Vu, T. , Simonin, J. , Vidick, G. , Bouslimani, N. , Desreux, J. (2012) From BTBPs to BTPhens: the effect of ligand pre-organization on the extraction properties of quadridentate bis-triazine ligands. Procedia Chemistry , 7 pp. 231-238. ISSN: 1876-6196 | doi: https://dx.doi.org/10.1016/j.proche.2012.10.038
Distler, P. , Spendlikova, I. , John, J. , Harwood, L. , Hudson, M. , Lewis, F. (2012) Influence of diluent alkyl substitution on the extraction of Am(III) and Eu(III) by a 6,6'-bis(1,2,4-triazinyl)-2,2'-bipyridine ligand dissolved in alkylated cyclohexanone diluents. Radiochimica Acta , 100 (10). pp. 747-752. ISSN: 0033-8230 | doi: https://dx.doi.org/10.1524/ract.2012.1949
Laventine, D. , Afsar, A. , Hudson, M. , Harwood, L. (2012) Tuning the solubilities of bis-triazinylphenanthroline ligands (BTPhens) and their complexes. Heterocycles ISSN: 1881-0942 | doi: https://dx.doi.org/10.3987/COM-12-S(N)102
Lewis, F. , Harwood, L. , Hudson, M. , Drew, M. , Sypula, M. , Modolo, G. , Whittaker, D. , Sharrad, C. , Videva, V. , Hubscher-Bruder, V. , Arnaud-Neu, F. (2012) Complexation of lanthanides, actinides and transition metal cations with a 6-(1,2,4-triazin-3-yl)-2,2′:6′,2′′-terpyridine ligand: implications for actinide(III)/lanthanide(III) partitioning. Dalton Transactions , 41 (30). pp. 9209-9219. ISSN: 1364-5447 | doi: https://dx.doi.org/10.1039/c2dt30522d
Silva, E. , Pye, R. , Brown, G. , Harwood, L. (2012) Towards the total synthesis of mycaperoxide B: probing biosynthetic rationale. European Journal of Organic Chemistry , 2012 (6). pp. 1209-1216. ISSN: 1099-0690 | doi: https://dx.doi.org/10.1002/ejoc.201101477
Lewis, F. , Harwood, L. , Hudson, M. , Distler, P. , John, J. , Stamberg, K. , Núñez, A. , Hitos, G. , Espartero, A. (2012) Synthesis and evaluation of lipophilic BTBP ligands for An/Ln separation in nuclear waste treatment: the effect of alkyl substitution on extraction properties and implications for ligand design. European Journal of Organic Chemistry , 2012 (8). pp. 1509-1519. ISSN: 1099-0690 | doi: https://dx.doi.org/10.1002/ejoc.201101576

Lewis, F. , Harwood, L. , Hudson, M. (2011) Synthesis of ligands for use in actinide extraction. | doi: WO/2011/077081
Sharrad, C. , Harwood, L. , Livens, F. (2011) Nuclear fuel cycles: interfaces with the environment. In: Harrison, R. and Hester, R. , (eds.) Nuclear power and the environment. Issues in Environmental Science and Technology pp. 40-56. ISBN: 9781849732888 | doi: https://dx.doi.org/10.1039/9781849732888-00040
Lewis, F. , Hudson, M. , Harwood, L. (2011) Development of highly selective ligands for separations of actinides from lanthanides in the nuclear fuel cycle. Synlett , 2011 (18). pp. 2609-2632. ISSN: 1437-2096 | doi: https://dx.doi.org/10.1055/s-0030-1289557
Harwood, L. , Lewis, F. , Hudson, M. , John, J. , Distler, P. (2011) The separation of americium(III) from europium(III) by two new 6,6'-bistriazinyl-2,2'-bipyridines in different diluents. Solvent Extraction and Ion Exchange , 29 (4). pp. 551-576. ISSN: 0736-6299 | doi: https://dx.doi.org/10.1080/10496475.2011.556989
Lewis, F. , Harwood, L. , Hudson, M. , Drew, M. , Desreux, J. , Vidick, G. , Bouslimani, N. , Modolo, G. , Wilden, A. , Sypula, M. , Vu, T. , Simonin, J. (2011) Highly efficient separation of actinides from lanthanides by a phenanthroline-derived bis-triazine ligand. Journal of the American Chemical Society , 133 (33). pp. 13093-13102. ISSN: 0002-7863 | doi: https://dx.doi.org/10.1021/ja203378m

Silva, E. , Pye, R. , Cardin, C. , Harwood, L. (2010) Probing a biomimetic approach to Mycaperoxide B: hydroperoxidation studies. Synlett (4). pp. 509-513. ISSN: 1437-2096 | doi: https://dx.doi.org/10.1055/s-0029-1219152
NDom, J. , Mbafor, J. , Meva'a, L. , Kakam, Z. , Phanuel, A. , Ndongo, E. , Harwood, L. , Mpondo, T. (2010) New alkamide and ent-kaurane diterpenoid derivatives from Senecio erechtitoides (Asteraceae) . Phytochemistry Letters , 3 (4). pp. 201-206. ISSN: 1874-3900 | doi: https://dx.doi.org/10.1016/j.phytol.2010.07.007
Lewis, F. , Harwood, L. , Hudson, M. , Drew, M. , Modolo, G. , Sypula, M. , Desreux, J. , Bouslimani, N. , Vidick, G. (2010) Interaction of 6,6′′-bis(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-1,2,4-benzotriazin-3-yl)-2,2′:6′,2′′-terpyridine (CyMe4-BTTP) with some trivalent ions such as lanthanide(iii) ions and americium(iii). Dalton Transactions , 39 (21). pp. 5172-5182. ISSN: 1364-5447 | doi: https://dx.doi.org/10.1039/B924988E
Chappell, D. , Drew, M. , Gibson, S. , Harwood, L. , Russell, A. (2010) Formal total synthesis of (±)-conduramine E utilising the Bryce-Smith-Gilbert photoamination reaction. Synlett (4). pp. 517-520. ISSN: 1437-2096 | doi: https://dx.doi.org/10.1055/s-0029-1219526

Marrero, . and Harwood, . (2009) Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction. Tetrahedron Letters , 50 (26). pp. 3574-3576. ISSN: 0040-4039 | doi: https://dx.doi.org/10.1016/j.tetlet.2009.03.063
Harwood, . , Mountford, . , Yan, . (2009) Morpholinone mediated oxazolone-free C-terminus amide coupling permitting a convergent strategy for peptide synthesis. Journal of Peptide Science , 15 (1). pp. 1-4. ISSN: 1075-2617 | doi: https://dx.doi.org/10.1002/psc.1080
Gan, . , Harwood, . , Richards, . , Smith, . , Vinader, . (2009) Cycloadditions of chiral carbonyl ylides with imine dipolarophiles as a route to enantiomerically pure alpha-amino-beta-hydroxy acids. Tetrahedron-Asymmetry , 20 (6-8). pp. 723-725. ISSN: 0957-4166 | doi: https://dx.doi.org/10.1016/j.tetasy.2009.02.029

Chen, . , Gan, . , Harwood, . (2008) Azide 1,3-dipolar cycloadditions to N-propynoyl and N-propenoyl (5R)-5-phenylmorpholin-2-one: diastereocontrolled aziridine formation . Synlett (14). pp. 2119-2121. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-2008-1078595

Harwood, L. and Yan, R. (2007) Asymmetric synthesis of peptides. | doi: EP1937708 A1

Brome, . , Harwood, . , Osborn, . (2006) Preparation of enantiopure long chain threo-2-amino-3-hydroxyesters via chiral morpholinone-derived azomethine ylids. Canadian Journal of Chemistry-Revue Canadienne De Chimie , 84 (10). pp. 1448-1455. ISSN: 0008-4042 | doi: https://dx.doi.org/10.1139/v06-121
Hudson, . , Boucher, . , Braekers, . , Desreux, . , Drew, . , Foreman, . , Harwood, . , Hill, . , Madic, . , Marken, . , Youngs, . (2006) New bis(triazinyl) pyridines for selective extraction of americium(III). New Journal of Chemistry , 30 (8). pp. 1171-1183. ISSN: 1144-0546 | doi: https://dx.doi.org/10.1039/b514108g
Drew, . , Harwood, . , Yan, . (2006) Synthesis of chiral 3,4,5,6-tetrahydro-1,4-thiazin-2-ones (thiamorpholin-2-ones)-novel heterocycles possessing enhanced carbonyl electrophilicity over their oxygen counterparts. Synlett (19). pp. 3259-3262. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-2006-951548
Draffin, . and Harwood, . (2006) Synthesis of enantiopure prolines via exo-stereoselective 1,3-dipolar cycloadditions to acetone-derived chiral stabilised azomethine ylides. Synlett , 2006 (6). pp. 857-860. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-2006-939054

Aldous, . , Drew, . , Draffin, . , Hamelin, . , Harwood, . , Thurairatnam, . (2005) 1,3-Dipolar cycloadditions to unsymmetrical ketone-derived chiral stabilized azomethine ylides: strategies for the synthesis of highly substituted amino acids. Synthesis-Stuttgart (19). pp. 3271-3278. ISSN: 0039-7881 | doi: https://dx.doi.org/10.1055/s-2005-918487
Harwood, . (2005) Ultra-high pressure as a mild synthetic tool. In: Chakravort, . , (eds.) New perspectives in the frontiers of chemical research. Golden Jubilee Commemorative Scientific Monograph pp. 1-24.

Romagnoli, . , van Baal, . , Price, . , Harwood, . , Hayes, . (2004) Chiral poly(aromatic amide ester) dendrimers bearing an amino acid derived C-3-symmetric core: synthesis and properties. European Journal of Organic Chemistry , 2004 (20). pp. 4148-4157. ISSN: 1434-193X | doi: https://dx.doi.org/10.1002/ejoc.200400390
Harwood, . , McKendrick, . , Whitehead, . (2004) Organic chemistry at a glance. Blackwell Publishing , Oxford. ISBN: 9780865427822

Romagnoli, . , Harwood, . , Hayes, . (2003) Synthesis of a novel class of chiral polyaromatic amide dendrimers bearing an amino acid derived C-3-symmetric core. Tetrahedron Letters , 44 (1). pp. 37-40. ISSN: 0040-4039 | doi: https://dx.doi.org/10.1016/S0040-4039(02)02518-2
Romagnoli, . , Ashton, . , Harwood, . , Philp, . , Price, . , Smith, . , Hayes, . (2003) Synthesis and properties of polyaromatic dendrimers possessing a repetitive amide-ester coupling sequence. Tetrahedron , 59 (22). pp. 3975-3988. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/s0040-4020(03)00466-6
El Kaim, . , Gautier, . , Grimaud, . , Harwood, . , Michaut, . (2003) The Mannich reaction of hydrazones: improved reactivity under solvent-free conditions. Green Chemistry , 5 (4). pp. 477-479. ISSN: 1463-9262 | doi: https://dx.doi.org/10.1039/b306242b
Begum, . , Box, . , Drew, . , Harwood, . , Humphreys, . , Lowes, . , Morris, . , Redon, . , Walker, . , Whitehead, . (2003) Difluorinated analogues of shikimic acid. Tetrahedron , 59 (26). pp. 4827-4841. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/S0040-4020(03)00697-5

Professor Laurence Harwood

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