Dr Andrew Russell
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+44 (0) 118 378 6234
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Lecturer
- Lecturer in Organic Chemistry
- School Director of Academic Tutoring (SDAT)
- Department Director of Academic Tutoring.
Office
G29Building location
ChemistryAreas of interest
Dr Russell's research centres upon synthetic methodology and natural products synthesis. Thermal cycloaddition reactions are being employed to synthesise AI-77-B, whilst photochemical methods are being used in approaches to stemodin, aphidicolin, fortamine and conduramine E.Asymmetric alkene-arene meta-photocycloadditions are being developed whilst chiral citrates have been developed for the syntheses of homocitrate, rhizoferrin and the side chains of homoharringtonine and anhydroharringtonine.
He headed the development of a Chemical Analysis Facility that encompasses laboratories for nuclear magnetic resonance (NMR), mass spectrometry, thermal analysis, molecular spectroscopy and X-ray diffraction.
Research centres and groups
Dr Russell is part of the Biomedical, Molecular and Analytical Chemistry research group.Learn more about our research groups
Publications
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Gavriel, A.
,
Sambrook, M.
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Russell, A.
,
Hayes, W.
ORCID: 0000-0003-0047-2991
(2022)
Recent advances in self-immolative linkers and their applications in polymeric reporting systems.
Polymer Chemistry
, 13
(22).
pp.
3188-3269.
ISSN:
1759-9954
|
doi:
https://dx.doi.org/10.1039/D2PY00414C
- Gavriel, A. , Leroux, F. , Khurana, G. , Lewis, V. , Chippindale, A. , Sambrook, M. , Hayes, W. , Russell, A. (2021) A self-immolative system for disclosure of reactive electrophilic alkylating agents: understanding the role of the reporter group. Journal of Organic Chemistry , 86 (15). pp. 10263-10279. ISSN: 0022-3263 | doi: https://dx.doi.org/10.1021/acs.joc.1c00996
- Acton, A. , Leroux, F. , Feula, A. , Melia, K. , Sambrook, M. , Hayes, W. , Russell, A. (2019) Self-immolative systems for the disclosure of reactive electrophilic alkylating agents. Chemical Communications , 55 pp. 5219-5222. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/C8CC09728C
- Babra, J. , Russell, A. , Smith, C. , Zhang, Y. (2018) Combining C-H functionalisation and flow photochemical heterocyclic metamorphosis (FP-HM) for the synthesis of benzo[1,3]oxazepines. Tetrahedron , 74 (38). pp. 5351-5357. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2018.05.066
- Biswas, S. , Ma, S. , Nuzzo, S. , Twamley, B. , Russell, A. , Platts, J. , Hartl, F. , Baker, R. (2017) Structural variability of 4f and 5f thiocyanate complexes and dissociation of uranium(III)–thiocyanate bonds with increased ionicity. Inorganic Chemistry , 56 (23). pp. 14426-14437. ISSN: 1520-510X | doi: https://dx.doi.org/10.1021/acs.inorgchem.7b01560
- Cranwell, P. and Russell, A. (2016) A hydrazine-free Wolff–Kishner reaction suitable for an undergraduate laboratory. Journal of Chemical Education , 93 (5). pp. 949-952. ISSN: 0021-9584 | doi: https://dx.doi.org/10.1021/acs.jchemed.5b00954
- Cranwell, P. , Russell, A. , Smith, C. (2016) Methyl hydrazinocarboxylate as a practical alternative to hydrazine in the Wolff–Kishner reaction. Synlett , 27 (1). pp. 131-135. ISSN: 0936-5214 | doi: https://dx.doi.org/10.1055/s-0035-1560805
- Blencowe, C. , Thornthwaite, D. , Hayes, W. , Russell, A. (2015) Self-immolative base-mediated conjugate release from triazolylmethylcarbamates. Organic and Biomolecular Chemistry , 13 (32). pp. 8703-8707. ISSN: 1477-0520 | doi: https://dx.doi.org/10.1039/c5ob00984g
- Cranwell, P. , Peterson, A. , Littlefield, B. , Russell, A. (2015) An operationally simple sonogashira reaction for an undergraduate organic chemistry laboratory class. Journal of Chemical Education ISSN: 0021-9584 | doi: https://dx.doi.org/10.1021/acs.jchemed.5b00030
- Blencowe, C. , Russell, A. , Greco, F. , Hayes, W. , Thornthwaite, D. (2011) Self-immolative linkers in polymeric delivery systems. Polymer Chemistry , 2 (4). pp. 773-790. ISSN: 1759-9954 | doi: https://dx.doi.org/10.1039/C0PY00324G
- Chappell, D. , Drew, M. , Gibson, S. , Harwood, L. , Russell, A. (2010) Formal total synthesis of (±)-conduramine E utilising the Bryce-Smith-Gilbert photoamination reaction. Synlett (4). pp. 517-520. ISSN: 1437-2096 | doi: https://dx.doi.org/10.1055/s-0029-1219526
- Ma, . , Porter, . , Chappell, . , Russell, . , Marston, . (2009) Mechanisms for the formation of organic acids in the gas-phase ozonolysis of 3-carene. Physical Chemistry Chemical Physics , 11 (21). pp. 4184-4197. ISSN: 1463-9076 | doi: https://dx.doi.org/10.1039/b818750a
- Ma, . , Russell, . , Marston, . (2008) Mechanisms for the formation of secondary organic aerosol components from the gas-phase ozonolysis of alpha-pinene. Physical Chemistry Chemical Physics , 10 (29). pp. 4294-4312. ISSN: 1463-9076 | doi: https://dx.doi.org/10.1039/b803283a
- Russell, . (2008) Alcohols: synthesis by addition to alkynes and alkenes. In: Clayden, . , Ley, . , Noyori, . , Regitz, . , Schaumann, . , Shinkai, . , Thomas, . , Trost, . , Reider, . , (eds.) Science of synthesis: Houben-Weyl methods of molecular transformation: alcohols. , 36. Thieme , New York. pp. 191-244. ISBN: 9783131188816
- Ma, . , Willcox, . , Russell, . , Marston, . (2007) Pinic and pinonic acid formation in the reaction of ozone with alpha-pinene. Chemical Communications (13). pp. 1328-1330. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/b617130c
- Ma, . , Luciani, . , Porter, . , Russell, . , Johnson, . , Marston, . (2007) Organic acid formation in the gas-phase ozonolysis of alpha-pinene. Physical Chemistry Chemical Physics , 9 (37). pp. 5084-5087. ISSN: 1463-9076 | doi: https://dx.doi.org/10.1039/b709880d
- Chappell, . and Russell, . (2006) From alpha-cedrene to crinipellin B and onward: 25 years of the alkene-arene meta-photocycloaddition reaction in natural product synthesis. Organic and Biomolecular Chemistry , 4 (24). pp. 4409-4430. ISSN: 1477-0520 | doi: https://dx.doi.org/10.1039/b614011b
- Ancliff, . , Russell, . , Sanderson, . (2006) Synthesis of the ester side chains of some potently antileukemic harringtonia alkaloids from chiral citrates. Chemical Communications , 2006 (30). pp. 3243-3245. ISSN: 1359-7345 | doi: https://dx.doi.org/10.1039/b605339d
- Tchabanenko, K. , Chesworth, R. , Parker, J. , Anand, N. , Russell, A. , Adlington, R. , Baldwin, J. (2005) Biomimetic approach to Galbulimina type I alkaloids. Tetrahedron , 61 (49). pp. 11649-11656. ISSN: 0040-4020 | doi: https://dx.doi.org/10.1016/j.tet.2005.09.050
- Boyd, . , Greaves, . , Kettle, . , Russell, . , Steed, . (2005) Alkene-arene meta photocycloadditions with a four-carbon-atom tether: efficient approach toward the polycyclic ring systems of aphidicolin and stemodinone. Angewandte Chemie-International Edition , 44 (6). pp. 944-946. ISSN: 1433-7851 | doi: https://dx.doi.org/10.1002/anie.200461661