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The IntFOLD Server Results Page (Version 3.0)

Please cite the following papers:

McGuffin, L.J., Atkins, J., Salehe, B.R., Shuid, A.N. & Roche, D.B. (2015) IntFOLD: an integrated server for modelling protein structures and functions from amino acid sequences. Nucleic Acids Research, 43, W169-73. PubMed

Buenavista, M. T., Roche, D. B. & McGuffin, L. J. (2012) Improvement of 3D protein models using multiple templates guided by single-template model quality assessment. Bioinformatics, 28, 1851-1857. PubMed

Links to graphical output:
Download machine readable results in CASP format:
Results will be available for 21 days after job completion (subject to server capacity)

Top 5 multi-template 3D models for CSRP3 | Help
Model ID and
PDBsum links for all templates used
Confidence
and P-value
Global model quality score Local model quality plot
(click images to download plots)
Model coloured by local quality
(click images to view models, local errors and target coverage interactively)
IntFOLD3
sp3
multi6
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
sp3
multi2
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
IntFOLDTS50
multi2
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
sp3
multi4
TS1

1b8tA
2rgtA
HIGH:
1.893E-3
0.5932
IntFOLD3
sp3
multi1
TS1

1b8tA
1b8tA2
HIGH:
1.893E-3
0.5932
Disorder prediction is carried out using DISOclust:
McGuffin, L. J. (2008) Intrinsic disorder prediction from the analysis of multiple protein fold recognition models. Bioinformatics, 24, 1789-1804. PubMed
Disorder prediction for CSRP3 | Help
Click image to download plot in PostScript format.
Domain boundary prediction for CSRP3 | Help
Click image to download model or view prediction using Jmol. The model above is coloured according to the predicted domains.
Ligand binding site prediction is carried out using FunFOLD:
Roche, D. B., Tetchner, S. J. & McGuffin, L. J. (2011) FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins. BMC Bioinformatics, 12, 160. PubMed
Ligand binding residues prediction for CSRP3 | Help
Click image to download model or view prediction using Jmol. Predicted ligand binding residues are shown as blue sticks in the image above.
Model quality assessment is carried out using ModFOLDclust2:
McGuffin, L. J. & Roche, D. B. (2010) Rapid model quality assessment for protein structure predictions using the comparison of multiple models without structural alignments. Bioinformatics, 26, 182-188. PubMed
Full model quality assessment results for CSRP3 | Help
Model ID and
PDBsum links for all templates used
Confidence
and P-value
Global model quality score Local model quality plot
(click images to download plots)
Model coloured by local quality
(click images to view models, local errors and target coverage interactively)
IntFOLD3
sp3
multi6
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
sp3
multi2
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
IntFOLDTS50
multi2
TS1

1b8tA
HIGH:
1.85E-3
0.5954
IntFOLD3
sp3
multi4
TS1

1b8tA
2rgtA
HIGH:
1.893E-3
0.5932
IntFOLD3
sp3
multi1
TS1

1b8tA
1b8tA2
HIGH:
1.893E-3
0.5932
IntFOLD3
IntFOLDTS130
multi4
TS1

1b8tA
HIGH:
1.96E-3
0.5899
IntFOLD3
IntFOLDTS130
multi1
TS1

1b8tA
HIGH:
1.96E-3
0.5899
IntFOLD3
COMA
multi8
TS1

1b8tA
HIGH:
1.968E-3
0.5895
IntFOLD3
COMA
multi6
TS1

1b8tA
HIGH:
1.968E-3
0.5895
IntFOLD3
COMA
multi4
TS1

1b8tA
HIGH:
1.968E-3
0.5895
IntFOLD3
COMA
multi2
TS1

1b8tA
HIGH:
1.968E-3
0.5895
IntFOLD3
HHsearch
multi7
TS1

1b8tA
1a7iA
HIGH:
2.02E-3
0.5870
IntFOLD3
HHsearch
multi3
TS1

1b8tA
1a7iA
HIGH:
2.02E-3
0.5870
IntFOLD3
wPPAS
multi6
TS1

1b8tA
HIGH:
2.043E-3
0.5858
IntFOLD3
wPPAS
multi2
TS1

1b8tA
HIGH:
2.043E-3
0.5858
IntFOLD3
Env-PPAS
multi6
TS1

1b8tA
HIGH:
2.043E-3
0.5858
IntFOLD3
Env-PPAS
multi2
TS1

1b8tA
HIGH:
2.043E-3
0.5858
IntFOLD3
HHsearch
multi8
TS1

1b8tA
HIGH:
2.051E-3
0.5855
IntFOLD3
HHsearch
multi6
TS1

1b8tA
HIGH:
2.051E-3
0.5855
IntFOLD3
HHsearch
multi4
TS1

1b8tA
HIGH:
2.051E-3
0.5855
IntFOLD3
HHsearch
multi2
TS1

1b8tA
HIGH:
2.051E-3
0.5855
IntFOLD3
MUSTER
multi6
TS1

1b8tA
HIGH:
2.056E-3
0.5852
IntFOLD3
MUSTER
multi2
TS1

1b8tA
HIGH:
2.056E-3
0.5852
IntFOLD3
LOMETS
multi2
TS1

1b8tA
HIGH:
2.056E-3
0.5852
IntFOLD3
IntFOLDTS130
multi2
TS1

1b8tA
HIGH:
2.056E-3
0.5852
IntFOLD3
LOMETS
multi4
TS1

1b8tA
HIGH:
2.085E-3
0.5839
IntFOLD3
LOMETS
multi1
TS1

1b8tA
HIGH:
2.085E-3
0.5839
IntFOLD3
dPPAS
multi5
TS1

1b8tA
HIGH:
2.15E-3
0.5810
IntFOLD3
PPAS
multi6
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
PPAS
multi2
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
dPPAS2
multi8
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
dPPAS2
multi6
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
dPPAS2
multi4
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
dPPAS2
multi2
TS1

1b8tA
HIGH:
2.177E-3
0.5797
IntFOLD3
wMUSTER
multi6
TS1

1b8tA
HIGH:
2.221E-3
0.5778
IntFOLD3
wMUSTER
multi2
TS1

1b8tA
HIGH:
2.221E-3
0.5778
IntFOLD3
IntFOLDTS50
multi4
TS1

1b8tA
HIGH:
2.418E-3
0.5696
IntFOLD3
IntFOLDTS50
multi1
TS1

1b8tA
HIGH:
2.418E-3
0.5696
IntFOLD3
wdPPAS
multi8
TS1

1b8tA
HIGH:
2.458E-3
0.5681
IntFOLD3
wdPPAS
multi6
TS1

1b8tA
HIGH:
2.458E-3
0.5681
IntFOLD3
wdPPAS
multi4
TS1

1b8tA
HIGH:
2.458E-3
0.5681
IntFOLD3
wdPPAS
multi2
TS1

1b8tA
HIGH:
2.458E-3
0.5681
IntFOLD3
wdPPAS
multi1
TS1

1b8tA
1ctlA
HIGH:
2.705E-3
0.5588
IntFOLD3
dPPAS
multi8
TS1

1b8tA
HIGH:
2.992E-3
0.5492
IntFOLD3
dPPAS
multi6
TS1

1b8tA
HIGH:
2.992E-3
0.5492
IntFOLD3
dPPAS
multi4
TS1

1b8tA
HIGH:
2.992E-3
0.5492
IntFOLD3
dPPAS
multi2
TS1

1b8tA
HIGH:
2.992E-3
0.5492
IntFOLD3
PPAS
multi4
TS1

1b8tA
2d8yA
HIGH:
3.569E-3
0.5322
IntFOLD3
PPAS
multi1
TS1

1b8tA
1ctlA
HIGH:
3.569E-3
0.5322
IntFOLD3
dPPAS2
multi1
TS1

1b8tA
1ctlA
HIGH:
3.569E-3
0.5322
IntFOLD3
Env-PPAS
multi4
TS1

1b8tA
2d8yA
HIGH:
3.624E-3
0.5307
IntFOLD3
Env-PPAS
multi1
TS1

1b8tA
1ctlA
HIGH:
3.624E-3
0.5307
IntFOLD3
sp3
multi7
TS1

1b8tA
1iml
1b8tA2
1b8tA1
HIGH:
4.158E-3
0.5175
IntFOLD3
sp3
multi3
TS1

1b8tA
1b8tA2
1iml
1b8tA1
HIGH:
4.158E-3
0.5175
IntFOLD3
IntFOLDTS50
multi3
TS1

1b8tA
2d8yA
1b8tA2
1b8tA1
HIGH:
4.436E-3
0.5113
IntFOLD3
spk2
multi4
TS1

1b8tA
2rgtA
HIGH:
5.36E-3
0.4931
IntFOLD3
spk2
multi1
TS1

1b8tA
1b8tA2
HIGH:
5.36E-3
0.4931
IntFOLD3
wMUSTER
multi7
TS1

1b8tA
2d8yA
1imlA
HIGH:
5.375E-3
0.4928
IntFOLD3
wMUSTER
multi3
TS1

1b8tA
2d8yA
1imlA
HIGH:
5.375E-3
0.4928
IntFOLD3
Env-PPAS
multi3
TS1

1b8tA
1imlA
2d8yA
HIGH:
5.939E-3
0.4832
IntFOLD3
spk2
multi7
TS1

1b8tA
1iml
1b8tA2
1b8tA1
HIGH:
6.596E-3
0.4731
IntFOLD3
spk2
multi8
TS1

1b8tA
2rgtA
HIGH:
8.404E-3
0.4498
IntFOLD3
spk2
multi5
TS1

1b8tA
1iml
HIGH:
8.404E-3
0.4498
IntFOLD3
dPPAS
multi7
TS1

1b8tA
2d8yA
HIGH:
9.764E-3
0.4354
IntFOLD3
dPPAS
multi3
TS1

1b8tA
2d8yA
HIGH:
9.764E-3
0.4354
IntFOLD3
dPPAS
multi1
TS1

1b8tA
2d8yA
HIGH:
9.764E-3
0.4354
IntFOLD3
spk2
multi6
TS1

1b8tA
HIGH:
9.906E-3
0.4340
IntFOLD3
spk2
multi2
TS1

1b8tA
HIGH:
9.906E-3
0.4340
IntFOLD3
spk2
multi3
TS1

1b8tA
1b8tA2
2co8A
1iml
1b8tA1
MEDIUM:
1.219E-2
0.4140
IntFOLD3
IntFOLDTS130
multi3
TS1

1b8tA
2d8yA
1b8tA2
1b8tA1
MEDIUM:
1.284E-2
0.4090
IntFOLD3
wdPPAS
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.419E-2
0.3994
IntFOLD3
wdPPAS
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.419E-2
0.3994
IntFOLD3
dPPAS2
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.472E-2
0.3959
IntFOLD3
dPPAS2
multi5
TS1

1b8tA
2d8yA
MEDIUM:
1.472E-2
0.3959
IntFOLD3
dPPAS2
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.472E-2
0.3959
IntFOLD3
PPAS
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.494E-2
0.3945
IntFOLD3
PPAS
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.494E-2
0.3945
IntFOLD3
IT3
TS1

MEDIUM:
1.554E-2
0.3907
IntFOLD3
LOMETS
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.577E-2
0.3893
IntFOLD3
Env-PPAS
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.612E-2
0.3872
IntFOLD3
IT3
TS5

MEDIUM:
1.682E-2
0.3830
IntFOLD3
wPPAS
multi7
TS1

1b8tA
2d8yA
1imlA
MEDIUM:
1.685E-2
0.3829
IntFOLD3
wPPAS
multi3
TS1

1b8tA
2d8yA
1imlA
MEDIUM:
1.685E-2
0.3829
IntFOLD3
COMA
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.73E-2
0.3804
IntFOLD3
COMA
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.73E-2
0.3804
IntFOLD3
IT3
TS3

MEDIUM:
1.745E-2
0.3795
IntFOLD3
MUSTER
multi7
TS1

1b8tA
2d8yA
MEDIUM:
1.792E-2
0.3769
IntFOLD3
MUSTER
multi3
TS1

1b8tA
2d8yA
MEDIUM:
1.792E-2
0.3769
IntFOLD3
IT3
TS4

MEDIUM:
2.026E-2
0.3652
IntFOLD3
wPPAS
multi8
TS1

1b8tA
2dfyX
MEDIUM:
2.178E-2
0.3582
IntFOLD3
wPPAS
multi5
TS1

1b8tA
2dfyX
MEDIUM:
2.178E-2
0.3582
IntFOLD3
wMUSTER
multi8
TS1

1b8tA
2dfyX
MEDIUM:
2.449E-2
0.3469
IntFOLD3
wMUSTER
multi5
TS1

1b8tA
2dfyX
MEDIUM:
2.449E-2
0.3469
IntFOLD3
MUSTER
multi8
TS1

1b8tA
2dfyX
MEDIUM:
2.476E-2
0.3458
IntFOLD3
MUSTER
multi5
TS1

1b8tA
2dfyX
MEDIUM:
2.476E-2
0.3458
IntFOLD3
HHsearch
multi5
TS1

1b8tA
2xjyA
MEDIUM:
2.492E-2
0.3452
IntFOLD3
HHsearch
multi1
TS1

1b8tA
4jcjA
MEDIUM:
2.532E-2
0.3437
IntFOLD3
IT3
TS2

MEDIUM:
2.705E-2
0.3374
IntFOLD3
COMA
multi1
TS1

1b8tA
2miuA
MEDIUM:
2.981E-2
0.3280
IntFOLD3
wMUSTER
multi4
TS1

1b8tA
2xqnT
2dfyX
MEDIUM:
3.317E-2
0.3177
IntFOLD3
wMUSTER
multi1
TS1

1b8tA
2xqnT
MEDIUM:
3.317E-2
0.3177
IntFOLD3
COMA
multi5
TS1

1b8tA
1rutX
MEDIUM:
3.327E-2
0.3174
IntFOLD3
wdPPAS
multi5
TS1

1b8tA
2xqnT
MEDIUM:
3.332E-2
0.3173
IntFOLD3
Env-PPAS
multi8
TS1

1b8tA
2dfyX
MEDIUM:
3.395E-2
0.3155
IntFOLD3
Env-PPAS
multi5
TS1

1b8tA
2dfyX
MEDIUM:
3.395E-2
0.3155
IntFOLD3
PPAS
multi8
TS1

1b8tA
2dfyX
MEDIUM:
3.609E-2
0.3096
IntFOLD3
PPAS
multi5
TS1

1b8tA
2dfyX
MEDIUM:
3.609E-2
0.3096
IntFOLD3
MUSTER
multi4
TS1

1b8tA
2dfyX
MEDIUM:
4.169E-2
0.2957
IntFOLD3
MUSTER
multi1
TS1

1b8tA
2xqnT
MEDIUM:
4.169E-2
0.2957
IntFOLD3
IT3
TS9

MEDIUM:
4.341E-2
0.2918
IntFOLD3
IT3
TS7

MEDIUM:
4.382E-2
0.2909
IntFOLD3
IT3
TS6

MEDIUM:
4.444E-2
0.2896
IntFOLD3
IT3
TS8

MEDIUM:
4.589E-2
0.2865
IntFOLD3
IT3
TS10

MEDIUM:
4.919E-2
0.2798
IntFOLD3
wPPAS
multi4
TS1

1b8tA
2dfyX
LOW:
5.119E-2
0.2760
IntFOLD3
wPPAS
multi1
TS1

1b8tA
2xqnT
LOW:
5.119E-2
0.2760
IntFOLD3
sp3
multi8
TS1

1b8tA
2rgtA
LOW:
5.492E-2
0.2692
IntFOLD3
sp3
multi5
TS1

1b8tA
2rgtA
LOW:
5.492E-2
0.2692

Contact

Tel: 0118 378 6332

Email: l.j.mcguffin
@reading.ac.uk

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