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Dr Sam Boateng

Portrait of Sam Boateng

Associate Professor in Biomedical Science

Admissions Tutor for Biomedical Sciences

Research centres and groups

International Collaborators

  • Professor Pieter de Tombe, Loyola University, Chicago
  • Dr Jody Martin , Loyola University, Chicago
  • Dr Robert Gaffin, University of Illinois at Chicago
  • Dr Masahiko Hoshijima, UCSD, USA

National Collaborators 

  • Dr Sassan Hafizi, University of Portsmouth 
  • Professor Ralph Knoell, Imperial College London

Research projects

  • Funding from British Heart Foundation
  • To study the process of cardiac cell adaptation, particularly in response to mechanical stress as a means to understanding the mechanisms associated with heart failure
  • Metabolism in heart failure
  • Re-modelling of cardiac fibroblasts
  • Role of circadian activity on myocardial growth and adaptation


Elected member of the British Society for Cardiovascular Research committee since 2011

Professional bodies/affiliations

Member of:

Selected publications


SY, Berlin JB, Geenen DL, Margulies KB, de Tombe PP and Russell B. Cardiac dysfunction and heart failure are associated with abnormalities in the subcellular distribution and amounts of oligomeric muscle LIM protein. Am J Physiol-Heart Circ Physiol 292(1):H259-69 (2007).

Lixin Qi and Boateng SY. The circadian protein Clock localizes to the sarcomeric Z-disk and is a sensor of myofilament cross-bridge activity in cardiac myocytes. Biochem Biophys Res Comm 352(4):1054-1059 (2006).

Lateef S, Boateng SY, Ahluwalia N, Hartman TJ, Hanley L and Russell B. Three-dimensional chemical structures by protein functionalised micron sized beads bound to polylysine coated silicone surfaces. J Biomed Mater Res A: 72A(4):373-80 (2005).

Boateng SY, Lateef S, Hartman TJ, Hanley L and Russell B. RGD and YIGSR synthetic peptides facilitate identical cellular adhesion as laminin and fibronectin but alter the physiology of neonatal cardiac myocytes. Am J Physiol Cell Physiol. (2005) Jan;288(1):C30-8. Epub 2004 Sep 15.

Boateng SY, Hartman TJ, Ahluwalia N, Vidula H, Desai TA and Russell B. Inhibition of fibroblast proliferation using silicone micropegs: Implications for cardiac tissue engineering and cell culturing. Am J Physiol-Cell Physiology 285:C171-C182 (2003).

Boateng S, Lateef SS, Crot CA, Motlagh D, Desai T, Samarel AM, Russell B and Hanley L. Peptides bound to silicone membranes and 3D micro fabrication for cardiac cell culture. Advanced Materials 14(6):461-463 (2002).

Lateef SS, Boateng S, Hartman TJ, Crot CA, Russell B and Hanley L. GRGDSP peptide bound silicone membranes withstand mechanical flexing in vitro and display enhanced fibroblast adhesion. Biomaterials 23:3159-3168 (2002).

Boateng SY, Naqvi R, Macleod K, Yacoub M and Boheler K. Short term low dose ramipril treatment normalises myocyte relaxation and calcium handling following cardiac hypertrophy in rats. Am J Physiol-Heart Circ Physiol 280(3):H1029-38 (2001).

Lateef S, Boateng S, Hartman T, Crot C, Russell B and Hanley L. Stretching and fibroblast growth on GRGDSP-peptide modified silicone membranes (Review). Polymeric materials: Science and Engineering 85:403-404 (2001).

Nikcevic G, Perhonen M, Boateng S and Russell B. Translation is regulated via the 3' untranslated region of α-myosin heavy chain mRNA by calcium, but not by its localization. J Muscle Res Cell Motil. 21(6):599-607 (2000).

Ribadeau-Dumas A, Brady M, Boateng SY, Schwartz K and Boheler KR. Sarco(Endo)plasmic reticulum Ca2+-ATPase (SERCA2) gene products are regulated post-transcriptionally during rat cardiac development. Cardiovas Res 43: 426-436 (1999).

Ationu A and Boateng S. The role of natriuretic peptides in cardiovascular disorders and human cardiac allografts (Review). Int J Mol Med 2: 235-239 (1998).

Boateng SY, Seymour A-M, Bhutta N, Dunn M, Yacoub M and Boheler K. Sub-antihypertensive doses of ramipril normalises calcium ATPase expression and function following cardiac hypertrophy in rats. J Mol Cell Cardiol. 30(12):2683-94 (1998).

Boateng S, Seymour A-M, Dunn M, Yacoub M and Boheler K. Inhibition of endogenous cardiac phosphatase activity and measurement of sarcoplasmic reticulum calcium uptake: a possible role of phospholamban phosphorylation in the hypertrophied myocardium. Biochem Biophys Res Comm 239: 701-705 (1997).

MU Koban, SY Boateng and K Boheler, The role of the sarcoplasmic reticulum calcium ATPase and its regulatory protein phospholamban in the developing myocardium. In: The Developing Heart (B.Ostadal: M. Nagano: N. Takeda: N.S Dhalla, eds) Lippincott-Ravens Publishers, New York, (1997).

Amarni M, Corbett J, Boateng SY, Dunn MJ and Yacoub MH. Kinetics of induction and protective effect of heat shock proteins following cardioplegic arrest. Ann-Thorac-Surg 61(5): 1407-11 (1996).

Amarni M, Corbett J, Allen NJ, O.Shea J, Boateng SY, May AJ, Dunn MJ and Yacoub MH. Induction of heat-shock proteins enhances myocardial and endothelial functional recovery after prolonged cardioplegic arrest. Ann-Thorac-Surg 57(1):157-160 (1994).

Impact, Enterprise and Outreach

Recent involvement with "Mending broken hearts" British Heart Foundation campaign

  • BHF Mending Broken Hearts Appeal
  • BHF Mending broken hearts campaign

Interviews with BBC television and radio

Recent activities at the university of Reading

  • Mending Broken Hearts campaign at the UoR


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