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Jay Mulley

Email:
g.mulley@reading.ac.uk
Phone:
+44 (0) 118 378 8893
Job title:
Lecturer

Responsibilities:

Lecturer in Biomedical Sciences
Programme Director for BSc Microbiology
Admissions Tutor for BSc Microbiology
PhD supervisor
Academic Tutor

Teaching

Part 0. Foundation Biology
Part 1. Introductory Microbiology (Convenor); Bacteriology & Virology (Convenor); Pathology
Part 2. Infectious Diseases (Convenor); Molecular Genetics; Marine Biology & Conservation
Part 3. Mechanisms for Microbial function; Applied and Integrated Biochemistry; Zoonotic Epidemiology

Final Year Research Project Supervisor

Research centres and groups

Member of the Microbiology Research Group

Research projects

Metal-ion based antimicrobials: mechanism of antibacterial action and resistance
Phage therapy: understanding bacteriophage diversity and bacteriophage-host interactions to improve application in treatment of bacterial infections
Photorhabdus-nematode symbiosis: molecular mechanisms involved in nematode mutualism, insect pathogenicity, evolution of human pathogenicity
Development of a virus-like particle (VLP) vaccine for Polio virus

Impact, enterprise and outreach

Lead Academic Developer of the Open Online Course (OOC) Small & Mighty: Introduction to Microbiology available on the FutureLearn platform

Publications

Hapeshi, A. , Healey, J. , Mulley, G. ORCID: 0000-0003-0650-478X , Waterfield, N. (2020) Temperature restriction in entomopathogenic bacteria. Frontiers in Microbiology , 11 ISSN: 1664-302X | doi: https://dx.doi.org/10.3389/fmicb.2020.548800
Storey, N. , Rabiey, M. , Neuman, B. , Jackson, R. , Mulley, G. ORCID: 0000-0003-0650-478X (2020) Genomic characterisation of mushroom pathogenic pseudomonads and their interaction with bacteriophages. Viruses , 12 (11). ISSN: 1999-4915 | doi: https://dx.doi.org/10.3390/v12111286

Bukhari, K. , Mulley, G. , Gulyaeva, A. , Zhao, L. , Shu, G. , Jiang, J. , Neuman, B. (2018) Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus. Virology , 524 pp. 160-171. ISSN: 0042-6822 | doi: https://dx.doi.org/10.1016/j.virol.2018.08.010

Westhoek, A. , Field, E. , Rehling, F. , Mulley, G. , Webb, I. , Poole, P. , Turnbull, L. (2017) Policing the legume-Rhizobium symbiosis: a critical test of partner choice. Scientific reports , 7 (1). ISSN: 2045-2322 | doi: https://dx.doi.org/10.1038/s41598-017-01634-2

Castagnola, A. , Mulley, G. , Davis, N. , Waterfield, N. , Stock, S. (2016) Transcript abundance of photorhabdus insect-related (Pir) toxin in Manduca sexta and Galleria mellonella infections. Toxins , 8 (10). ISSN: 2072-6651 | doi: https://dx.doi.org/10.3390/toxins8100287

Nollmann, F. , Dauth, C. , Mulley, G. ORCID: 0000-0003-0650-478X , Kegler, C. , Kaiser, M. , Waterfield, N. , Bode, H. (2015) Insect-specific production of new GameXPeptides in Photorhabdus luminescens TTO1, widespread natural products in entomopathogenic bacteria. ChemBioChem , 16 (2). pp. 205-208. ISSN: 1439-7633 | doi: https://dx.doi.org/10.1002/cbic.201402603
Mulley, G. , Beeton, M. , Wilkinson, P. , Vlisidou, I. , Ockendon-Powell, N. , Hapeshi, A. , Tobias, N. , Nollmann, F. , Bode, H. , van den Elsen, J. , ffrench-Constant, R. , Waterfield, N. , eds. (2015) From insect to man: Photorhabdus sheds light on the emergence of human pathogenicity. In: Skurnik, M. , (eds.) PLoS ONE , 10 (12). ISSN: 1932-6203 | doi: https://dx.doi.org/10.1371/journal.pone.0144937
Taylor, T. , Mulley, G. , McGuffin, L. , Johnson, L. , Brockhurst, M. , Arseneault, T. , Silby, M. , Jackson, R. (2015) Evolutionary rewiring of bacterial regulatory networks. Microbial Cell , 2 (7). pp. 256-258. ISSN: 2311-2638 | doi: https://dx.doi.org/10.15698/mic2015.07.215
Taylor, T. , Mulley, G. , Dills, A. , Alsohim, A. , McGuffin, L. ORCID: 0000-0003-4501-4767 , Studholme, D. , Silby, M. , Brockhurst, M. , Johnson, L. ORCID: 0000-0002-0006-1511 , Jackson, R. (2015) Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system. Science , 347 (6225). pp. 1014-1017. ISSN: 0036-8075 | doi: https://dx.doi.org/10.1126/science.1259145

Prell, J. , Mulley, G. ORCID: 0000-0003-0650-478X , Haufe, F. , White, J. , Williams, A. , Karunakaran, R. , Downie, J. , Poole, P. (2012) The PTS(Ntr) system globally regulates ATP-dependent transporters in Rhizobium leguminosarum. Molecular Microbiology , 84 (1). pp. 117-129. ISSN: 0950-382X | doi: https://dx.doi.org/10.1111/j.1365-2958.2012.08014.x

Zhou, J. , Loftus, A. , Mulley, G. ORCID: 0000-0003-0650-478X , Jenkins, A. (2011) A thin film detection/response system for pathogenic bacteria. Journal of the American Chemical Society , 132 (18). pp. 6566-6570. ISSN: 0002-7863 | doi: https://dx.doi.org/10.1021/ja101554a
Poulter, N. , Donaldson, M. , Mulley, G. ORCID: 0000-0003-0650-478X , Duque, L. , Waterfield, N. , Shard, A. , Spencer, S. , Jenkins, A. , Johnson, A. (2011) Plasma deposited metal Schiff-base compounds as antimicrobials. New Journal of Chemistry , 35 (7). pp. 1477-1484. ISSN: 1144-0546 | doi: https://dx.doi.org/10.1039/c1nj20091g
Mulley, G. ORCID: 0000-0003-0650-478X , White, J. , Karunakaran, R. , Prell, J. , Bourdes, A. , Bunnewell, S. , Hill, L. , Poole, P. (2011) Mutation of GOGAT prevents pea bacteroid formation and N2 fixation by globally downregulating transport of organic nitrogen sources. Molecular Microbiology , 80 (1). pp. 149-167. ISSN: 0950-382X | doi: https://dx.doi.org/10.1111/j.1365-2958.2011.07565.x

Mulley, G. ORCID: 0000-0003-0650-478X , Lopez-Gomez, M. , Zhang, Y. , Terpolilli, J. , Prell, J. , Finan, T. , Poole, P. (2010) Pyruvate is synthesized by two pathways in pea bacteroids with different efficiencies for nitrogen fixation. Journal of Bacteriology , 192 (19). pp. 4944-4953. ISSN: 1098-5530 | doi: https://dx.doi.org/10.1128/JB.00294-10