- School Director for Outreach
- Project co-founder of ReadiLab Initiative
- Contributor to Reading Scholars' Program
Dyan Sellayah

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Associate Professor
- Module convenor for BI3BA7-Medical Genetics (year 3), BI3EM1-Evolutionary Medicine (year 3)
- Admissions Tutor & Program Director for Medical Sciences
Teaching
Part 3: Medical GeneticsResearch centres and groups
National Collaborators
- Prof Roger Cox (MRC Harwell)
- Dr Felino Cagampang (University of Southampton)
- Prof Dame Frances Ashcroft (University of Oxford)
Research projects
Dr. Sellayah's research aims to investigate the molecular mechanisms that govern fat (adipose) tissue development and function in the context of obesity. His specific focus is in:
- Investigating the developmental programming of brown adipose tissue thermogenesis.
- Assessing the Impact of maternal nutrition during development on offspring adipose tissue development and function.
- Elucidating the function of FTO in adipogenesis
- Establishing the therapeutic potential of metformin's effects on adipose tissue
- Evolutionary origins of obesity
Awards and honours
Esteem Factors
- Recipient of the MRC New Investigator Research Grant award (2017) of £409,989
- Junior Research Fellow, Linacre College, University of Oxford 2014-2015
- Paper selected in top 5 basic research articles of 2014 in the journal Endocrinology
- Research highlight, Nature Medicine:17:1356, 2011
Impact, enterprise and outreach
Publications
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Gaspar, R.
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Unsworth, A.
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Al-Dibouni, A.
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Bye, A.
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Sage, T.
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Stewart, M.
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Cox, R.
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Gibbins, J.
ORCID: 0000-0002-0372-5352 , Sellayah, D. , Hughes, C.
ORCID: 0000-0002-9790-5820 (2021) Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring. Scientific Reports , 11 ISSN: 2045-2322 | doi: https://dx.doi.org/10.1038/s41598-020-80373-3
- Al-Dibouni, A. , Gaspar, R. , Ige, S. , Boateng, S. , Cagampang, F. , Gibbins, J. , Cox, R. , Sellayah, D. (2020) Unique genetic and histological signatures of mouse pericardial adipose tissue. Nutrients , 12 (6). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu12061855
- Sellayah, D. , Thomas, H. , Lanham, S. , Cagampang, F. (2019) Maternal obesity during pregnancy and lactation influences offspring obesogenic adipogenesis but not developmental adipogenesis in mice. Nutrients , 11 (3). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu11030495
- Sellayah, D. (2019) The impact of early human migration on brown adipose tissue evolution and its relevance to the modern obesity pandemic. Journal of the Endocrine Society , 3 (2). pp. 372-386. ISSN: 2472-1972 | doi: https://dx.doi.org/10.1210/js.2018-00363
- Sellayah, D. and Cagampang, F. (2018) The divergent effect of maternal protein restriction during pregnancy and postweaning high-fat diet feeding on blood pressure and adiposity in adult mouse offspring. Nutrients , 10 (12). ISSN: 2072-6643 | doi: https://dx.doi.org/10.3390/nu10121832
- Merkestein, M. and Sellayah, D. (2015) Role of FTO in adipocyte development and function: recent insights. International Journal of Endocrinology , 2015 ISSN: 1687-8337 | doi: https://dx.doi.org/10.1155/2015/521381
- Merkestein, M. , Laber, S. , McMurray, F. , Andrew, D. , Gregor, S. , Sanderson, J. , Li, M. , Usher, S. , Sellayah, D. , Ashcroft, F. , Cox, R. (2015) FTO influences adipogenesis by regulating mitotic clonal expansion. Nature Communications , 6 ISSN: 2041-1723 | doi: https://dx.doi.org/10.1038/ncomms7792
- Sellayah, D. and Sikder, D. (2014) Orexin restores aging-related brown adipose tissue dysfunction in male mice. Endocrinology , 155 (2). pp. 485-501. ISSN: 1945-7170 | doi: https://dx.doi.org/10.1210/en.2013-1629
- Sellayah, D. , Dib, L. , Anthony, F. , Watkins, A. , Flemming, T. , Hanson, M. , Cagampang, F. (2014) Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding of diet-induced thermogenesis in adult mouse offspring. European Journal of Nutrition , 53 (7). pp. 1523-1531. ISSN: 1436-6215 | doi: https://dx.doi.org/10.1007/s00394-014-0657-4
- Sellayah, D. , Cagampang, F. , Cox, R. (2014) On the evolutionary origins of obesity: a new hypothesis. Endocrinology , 155 (5). pp. 1573-1588. ISSN: 1945-7170 | doi: https://dx.doi.org/10.1210/en.2013-2103
- Merkestein, M. , Cagampang, F. , Sellayah, D. (2014) Fetal programming of adipose tissue function: an evolutionary perspective. Mammalian Genome , 25 (9-10). pp. 413-423. ISSN: 1432-1777 | doi: https://dx.doi.org/10.1007/s00335-014-9528-9