Staff Profile:Dr Vitaliy Khutoryanskiy
- Name:
- Dr Vitaliy Khutoryanskiy
- Job Title:
- Reader in Pharmaceutical Materials
- Responsibilities:
School of Pharmacy Director of Postgraduate Studies
Module convenor PM2PH2
- Areas of Interest:
- Polymers for pharmaceutical applications
- Mucoadhesive drug delivery systems
- Water-soluble polymers, amphiphilic polymers and polymeric complexes
- Hydrogels, biomaterials & polymeric blends
- Polymer colloids
- Stimuli-responsive polymers
- Ocular drug delivery
- Cationic polymers for gene delivery
- Research groups / Centres:
- Publications:
-
1 edited book, 80 original research papers, 5 reviews and 3 book chapters.
Selected recent publications are listed below:
1. Irmukhametova G.S., Fraser B., Keddie J.L., Mun G.A., Khutoryanskiy V.V.* The hydrogen bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surfaces, Langmuir, la-2011-038735.R2, accepted (2011)
2. Hall D.J., Khutoryanskaya O.V., Khutoryanskiy V.V.* Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems, Soft Matter, 7, 9620-9623 (2011)
3. Irmukhametova G.S., Mun G.A., Khutoryanskiy V.V.* Thiolated mucoadhesive and PEGylated non-mucoadhesive organosilica nanoparticles from 3-mercaptopropyl-trimethoxysilane, Langmuir, 27, 9551-9556 (2011).
4. Cook M., Tzortzis G., Charalampopoulos D., Khutoryanskiy V.V. Production and Evaluation of Dry Alginate - Chitosan Microcapsules as an Enteric Delivery Vehicle for Probiotic Bacteria, Biomacromolecules, 12, 2834-2840 (2011)
5. Khutoryanskiy V.V. Advances in mucoadhesion and mucoadhesive polymers, Macromol. Biosci., 11, 748-764 (2011)
6. Zhunuspayev D.E., Mun G.A., Khutoryanskiy V.V. Temperature-Responsive Properties and Drug Solubilization Capacity of Amphiphilic Copolymers Based on N-Vinylpyrrolidone and Vinyl Propyl Ether, Langmuir, 26, 7590-7597 (2010)
7. Khutoryanskaya O.V., Potgieter M., Khutoryanskiy V.V. Multilayered hydrogel coatings covalently-linked to glass surfaces showing a potential to mimic mucosal tissues, Soft Matter, 6, 551-557 (2010)
8. Sogias I.A., Khutoryanskiy V.V., Williams A.C. Exploring the factors affecting the solubility of chitosan in water, Macromol. Chem. Phys., 211, 426-433 (2010).
9. Al-Saadi A., Yu C.H., Khutoryanskiy V.V., Shih S.-J., Crossley A., Tsang S.C. Layer-by-layer electrostatic entrapment of protein molecules on superparamagnetic nanoparticle: new strategy to enhance adsorption capacity and maintain biological activity, J. Phys. Chem. C., 113, 15260-15265 (2009)
10. Aravindan L., Bicknell K.A., Brooks G., Khutoryanskiy V.V., Williams A.C. Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine, Int. J. Pharm., 378, 201-210 (2009)
11. Sogias I.A., Williams A.C., Khutoryanskiy V.V. Why is chitosan mucoadhesive? Biomacromolecules, 9, 1837-1842 (2008)
12. Zhunuspayev D.E., Mun G.A., P. Hole, Khutoryanskiy V.V. Solvent effects on the formation of nanoparticles and multilayered coatings based on hydrogen-bonded interpolymer complexes of poly(acrylic acid) with homo- and copolymers of N-vinyl pyrrolidone, Langmuir, 24, 13742-13747 (2008)
13. Khutoryanskaya O.V., Mayeva Z.A., Mun G.A., Khutoryanskiy V.V. Designing temperature-responsive biocompatible copolymers and hydrogels based on 2-hydroxyethyl(meth)acrylates, Biomacromolecules, 9, 3353-3361 (2008)
14. Khutoryanskaya O.V., Williams A.C., Khutoryanskiy V.V. pH-mediated interactions between poly(acrylic acid) and methylcellulose in the formation of ultrathin multilayered hydrogels and spherical nanoparticles, Macromolecules, 40, 7707-7713 (2007).
15. Khutoryanskiy V.V. Hydrogen-bonded interpolymer complexes as materials for pharmaceutical applications, Int. J. Pharm., 334, 1-2, 15-26 (2007)
16. Dubolazov A.V., Nurkeeva Z.S., Mun G.A., Khutoryanskiy V.V. Design of mucoadhesive films based on poly(acrylic acid) and hydroxypropyl cellulose, Biomacromolecules, 7, 1637-1643 (2006).
17. Qu X., Khutoryanskiy V.V., Stewart A., Rahman S., Sternberg B., Dufes C., McCarthy D., Wilson C.G., Lyons R., Carter C., Schatzlein A., Uchegbu I.F. Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude, Biomacromolecules, 7, 3452-3459 (2006).
Complete list of publications can be found here: Khutoryanskiy publications
