Staff Profile:Professor Mark Pagel
- Name:
- Professor Mark Pagel
- Job Title:
- Academic, Philip Lyle Building
- Responsibilities:
- Areas of Interest:
Head of Bioinformatics Laboratory
Molecular Evolution and Adaptation
- genome organisation
- genomic imprinting
- genomic conflict
- prion protein evolution
Statistical Methods for Comparative Studies
- methods of analysis for discrete and continuously varying characters
- reconstruction of ancestral character states
- Markov-chain monte carlo methods for comparative studies
Evolutionary Theory and Behavioural Ecology
- signalling theory
- arms races
Linguistic Evolution
- language phylogenies
- language evolution
- Research groups / Centres:
- Evolutionary biology research
- Publications:
-
YNumber of items: 52.
2013
- Pagel, M., Atkinson, Q. D., S. Calude, A. and Meade, A. (2013) Ultraconserved words point to deep language ancestry across Eurasia. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424 doi: 10.1073/pnas.1218726110
2011
- Venditti, C., Meade, A. and Pagel, M. (2011) Multiple routes to mammalian diversity. Nature, 479. pp. 393-396. ISSN 0028-0836 doi: 10.1038/nature10516
- Wilson Sayres, M. A., Venditti, C., Pagel, M. and Makova, K. D. (2011) Do variations in substitution rates and male mutation bias correlate with life-history traits? A study of 32 mammalian genomes. Evolution, 65 (10). pp. 2800-2815. ISSN 1558-5646 doi: 10.1111/j.1558-5646.2011.01337.x
- Gomes, N. M. V., Ryder, O. A., Houck, M. L., Charter, S. J., Walker, W., Forsyth, N. R., Austad, S. N., Venditti, C., Pagel, M., Shay, J. W. and Wright, W. E. (2011) Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination. Aging cell, 10 (5). pp. 761-768. ISSN 1474-9718 doi: 10.1111/j.1474-9726.2011.00718.x
2010
- Venditti, C. and Pagel, M. (2010) Speciation as an active force in promoting genetic evolution. Trends in Ecology & Evolution, 25 (1). pp. 14-20. ISSN 0169-5347 doi: 10.1016/j.tree.2009.06.010
- Venditti, C., Meade, A. and Pagel, M. (2010) Phylogenies reveal new interpretation of speciation and the Red Queen. Nature, 463 (7379). pp. 349-352. ISSN 0028-0836 doi: 10.1038/nature08630
2009
- Organ, C. L., Janes, D. E., Meade, A. and Pagel, M. (2009) Genotypic sex determination enabled adaptive radiations of extinct marine reptiles. Nature, 461 (7262). pp. 389-392. ISSN 0028-0836 doi: 10.1038/nature08350
- Pagel, M. (2009) Human language as a culturally transmitted replicator. Nature Reviews Genetics, 10 (6). pp. 405-415. ISSN 1471-0056 doi: 10.1038/nrg2560
- Pagel, M. (2009) Insight overview: natural selection 150 years on. Nature, 457 (7231). pp. 808-811. ISSN 0028-0836 doi: 10.1038/nature07889
- Pagel, M. (2009) Natural selection 150 years on. Nature, 457 (7231). pp. 808-811. ISSN 0028-0836 doi: 10.1038/nature07889
2008
- Venditti, C. and Pagel, M. (2008) Evolution in fits and starts. The Biologist, 55 (3). pp. 140-146.
- Atkinson, Q. D., Meade, A., Venditti, C., Greenhill, S. J. and Pagel, M. (2008) Languages evolve in punctuational bursts. Science, 319 (5863). p. 588. ISSN 0036-8075 doi: 10.1126/science.1149683
- Venditti, C. and Pagel, M. (2008) Model misspecification not the node-density artifact. Evolution, 62 (8). pp. 2125-2126. ISSN 0014-3820 doi: 10.1111/j.1558-5646.2008.00407.x
- Pagel, M. and Meade, A. (2008) Modelling heterotachy in phylogenetic inference by reversible-jump Markov chain Monte Carlo. Philosophical Transactions of the Royal Society B-Biological Sciences, 363 (1512). pp. 3955-3964. ISSN 0962-8436 doi: 10.1098/rstb.2008.0178
- Atkinson, Q. D., Meade, A., Venditti, C., Greenhill, S. J. and Pagel, M. (2008) Parsing the evolution of language - Response. Science, 320 (5875). p. 446. ISSN 0036-8075
- Venditti, C., Meade, A. and Pagel, M. (2008) Phylogenetic mixture models can reduce node-density artifacts. Systematic Biology, 57 (2). pp. 286-293. ISSN 1063-5157 doi: 10.1080/10635150802044045
- Freckleton, R. P., Phillimore, A. B. and Pagel, M. (2008) Relating traits to diversification: A simple test. American Naturalist, 172 (1). pp. 102-115. ISSN 0003-0147 doi: 10.1086/588076
- Pagel, M. (2008) Rise of the digital machine. Nature, 452 (7188). p. 699. ISSN 0028-0836 doi: 10.1038/452699a
- Venditti, C. and Pagel, M. (2008) Speciation and bursts of evolution. Evolution: Education and Outreach, 1 (3). pp. 274-280. ISSN 1936-6426 doi: 10.1007/s12052-008-0049-4
- Pagel, M. and Pomiankowski, A. (2008) The organismal prospect. In: M., P. and Pomiankowski, A. (eds.) Evolutionary Genomics and Proteomics. Sinauer, Sunderland MA, pp. 1-10. ISBN 9780878936540
- Meade, A. and Pagel, M. (2008) A phylogenetic mixture model for heterotachy. In: Pontarotti, P. (ed.) Evolutionary Biology from Concept to Application. Springer Verlag, Heidelberg, 29-41 . ISBN 9783642009518
- Pagel, M. and Atkinson, Q. D. (2008) The potential for genetic adaptations to language. Behavioral and Brain Sciences, 31 (5). 529-+. ISSN 0140-525X doi: 10.1017/s0140525x08005207
2007
- Pagel, M., Meade, A. and Scott, D. (2007) Assembly rules for protein networks derived from phylogenetic-statistical analysis of whole genomes. Bmc Evolutionary Biology, 7. p. 11. ISSN 1471-2148 doi: 10.1186/1471-2148-7-s1-s16
- Barker, D., Meade, A. and Pagel, M. (2007) Constrained models of evolution lead to improved prediction of functional linkage from correlated gain and loss of genes. Bioinformatics, 23 (1). pp. 14-20. ISSN 1367-4803 doi: 10.1093/bioinformatics/btl558
- Pagel, M., Atkinson, Q. D. and Meade, A. (2007) Frequency of word-use predicts rates of lexical evolution throughout Indo-European history. Nature, 449 (7163). 717-U7. ISSN 0028-0836 doi: 10.1038/nature06176
- Sibly, R. M., Barker, D., Hone, J. and Pagel, M. (2007) On the stability of populations of mammals, birds, fish and insects. Ecology Letters, 10 (10). pp. 970-976. ISSN 1461-023X doi: 10.1111/j.1461-0248.2007.01092.x
- Organ, C. L., Shedlock, A. M., Meade, A., Pagel, M. and Edwards, S. V. (2007) Origin of avian genome size and structure in non-avian dinosaurs. Nature, 446 (7132). pp. 180-184. ISSN 0028-0836 doi: 10.1038/nature05621
2006
- Pagel, M. and Meade, A. (2006) Bayesian analysis of correlated evolution of discrete characters by reversible-jump Markov chain Monte Carlo. American Naturalist, 167 (6). pp. 808-825. ISSN 0003-0147 doi: 10.1086/503444
- Pagel, M. (2006) Darwinian cultural evolution rivals genetic evolution. Behavioral and Brain Sciences, 29 (4). p. 360. ISSN 0140-525X
- Pagel, M. (2006) Darwinism and its discontents. Nature, 443 (7107). p. 31. ISSN 0028-0836 doi: 10.1038/443031b
- Venditti, C., Meade, A. and Pagel, M. (2006) Detecting the node-density artifact in phylogeny reconstruction. Systematic Biology, 55 (4). pp. 637-643. ISSN 1063-5157 doi: 10.1080/10635150600865567
- Pagel, M. (2006) Editorial: evolution, bioinformatics, and EBO. Evolutionary Bioinformatics Online , 2. pp. 357-358. ISSN 1176-9343
- Pagel, M. and Meade, A. (2006) Estimating rates of lexical replacement on phylogenetic trees of languages. In: Forster, P. and Renfrew, C. (eds.) Phylogenetic methods and the prehistory of languages. McDonald institute Monographs, pp. 173-182. ISBN 9781902937335
- Lumbsch, H. T., Schmitt, I., Barker, D. and Pagel, M. (2006) Evolution of micromorphological and chemical characters in the lichen-forming fungal family Pertusariaceae. Biological Journal of the Linnean Society, 89 (4). pp. 615-626. ISSN 0024-4066 doi: 10.1111/j.1095-8312.2006.00696.x
- Pagel, M., Venditti, C. and Meade, A. (2006) Large punctuational contribution of speciation to evolutionary divergence at the molecular level. Science, 314 (5796). pp. 119-121. ISSN 0036-8075 doi: 10.1126/science.1129647
- Sibly, R. M., Barker, D., Denham, M. C., Hone, J. and Pagel, M. (2006) Response to comment on "On the regulation of populations of mammals, birds, fish, and insects''. Science, 313 (5783). p. 45. ISSN 0036-8075
- Sibly, R. M., Barker, D., Denham, M. C., Hone, J. and Pagel, M. (2006) Response to comments on "On the regulation of populations of mammals, birds, fish, and insects". Science, 311 (5764). p. 1. ISSN 0036-8075 doi: 10.1126/science.1121565
- Lester, L., Meade, A. and Pagel, M. (2006) The slow road to the eukaryotic genome. Bioessays, 28 (1). pp. 57-64. ISSN 0265-9247 doi: 10.1002/bies.20344
2005
- Pagel, M. and Meade, A. (2005) Bayesian estimation of correlated evolution across cultures: a case study of marriage systems and wealth transfer at marriage. In: Mace, R., Holden, C.J. and Shennan, S. (eds.) The Evolution of Cultural Diversity: a phylogenetic approach. University College London Press, London, pp. 235-256. ISBN 9781844720651
- Pagel, M. and Meade, A. (2005) Mixture models in phylogenetic inference. In: Gascuel, O. (ed.) Mathematics of Evolution and Phylogeny. Oxford University Press, pp. 121-142. ISBN 9780198566106
- Sibly, R. M., Barker, D., Denham, M. C., Hone, J. and Pagel, M. (2005) On the regulation of populations of mammals, birds, fish, and insects. Science, 309 (5734). pp. 607-610. ISSN 0036-8075 doi: 10.1126/science.1110760
- Barker, D. and Pagel, M. (2005) Predicting functional gene links from phylogenetic-statistical analyses of whole genomes. PLoS Computational Biology, 1 (1). pp. 24-31. ISSN 1553-734X doi: 10.1371/journal.pcbi.0010003
2004
- Pagel, M., Meade, A. and Barker, D. (2004) Bayesian estimation of ancestral character states on phylogenies. Systematic Biology, 53 (5). pp. 673-684. ISSN 1063-5157 doi: 10.1080/10635150490522232
- Pagel, M. (2004) Limpets break Dollo's law. Trends in Ecology & Evolution, 19 (6). pp. 278-280. ISSN 0169-5347 doi: 10.1016/j.tree.2004.03.020
- Webster, A. J., Payne, R. and Pagel, M. (2004) Response to comments on "Molecular phylogenies link rates of evolution and speciation". Science, 303 (5655). p. 2. ISSN 0036-8075 doi: 10.1126/science.1091131
- Pagel, M. and Mace, R. (2004) The cultural wealth of nations. Nature, 428 (6980). pp. 275-278. ISSN 0028-0836 doi: 10.1038/428275a
- Pagel, M. and Bodmer, W. (2004) The evolution of human hairlessness: cultural adaptations and the ectoparasite hypothesis. In: Wasser, S.P. (ed.) Evolutionary Theory and Processes: Modern Horizons (papers in honour of Eviatar Nevo). Kluwer Academic Publishers., London, pp. 329-336. ISBN 140201693X
- Pagel, M. and Meade, A. (2004) A phylogenetic mixture model for detecting pattern-heterogeneity in gene sequence or character-state data. Systematic Biology, 53 (4). pp. 571-581. ISSN 1063-5157 doi: 10.1080/10635150490468675
2003
- Freckleton, R. P., Harvey, P. H. and Pagel, M. (2003) Bergmann's rule and body size in mammals. American Naturalist, 161 (5). pp. 821-825. ISSN 0003-0147 doi: 10.1111/j.1466-8238.2007.00363.x
- Pagel, M. (2003) Evolutionary biology: polygamy and parenting. Nature, 424 (6944). pp. 23-24. ISSN 0028-0836 doi: 10.1038/424023a
- Webster, A. J., Payne, R. J. H. and Pagel, M. (2003) Molecular phylogenies link rates of evolution and speciation. Science, 301 (5632). p. 478. ISSN 0036-8075 doi: 10.1126/science.1083202
- Pagel, M. and Bodmer, W. (2003) A naked ape would have fewer parasites. Proceedings of the Royal Society of London Series B-Biological Sciences, 270 (Suppl 1). S117-S119. ISSN 0962-8452 doi: 10.1098/rsbl.2003.0041