Staff Profile:Dr Wing-Man Lau

Areas of Interest:

Transdermal and topical drug delivery: Delivery of drugs via the skin is advantageous because it avoids first-pass metabolism and minimises systemic side effects. However, the outer skin barrier prevents effective drug uptake. The focus of this work is on the use of sophisticated drug design and delivery systems (e.g. pro-drugs/co-drugs; biologically/mechanically triggered, site-specific drug release from polymers) to overcome the outer skin barrier.

Drug toxicity testing: Our work focuses on the impact of the drug system at the cellular level using a range of tissue culture and molecular biology techniques including immunocytochemistry, flow cytometry and Western Blot analysis. The ultimate aim is to improve drug formulation, bioavailability, safety and patient acceptability.

Wound healing: In this work, we study the cellular effects of different wound healing treatments (including hyperbaric oxygen therapy) using monolayer cell cultures and to understand the cellular mechanisms underpinning the wound healing process.

Other research interests are:

Clinical practice research: This work involves promoting the effective use of drugs in the primary and secondary care settings, by enhancing the roles of various healthcare professionals in patient education. This is done by identifying the current barriers to effective drug use and raising public awareness on avoiding adverse effects and improving dosing accuracy.

Pharmacy Education: I also have interest in the use of technology in pharmacy education, investigating the benefit of various teaching methods and their impact in enhancing teaching and learning environment.

Research groups / Centres:
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This list was generated on Mon Feb 19 00:56:24 2018 UTC.

Conference presentations

Mockaityte, I, Ng, KW, Lau, WM. (Podium) Controlled topical antioxidant delivery to the skin using the co-drug approach (Podium). APS PharmSci 2013, Edinburgh, UK. Sep 2013

Khateb, KA, Lau, WM, Khutoryanskiy, V. Synthesising and characterising a new temperature responsive triblock copolymer based on PNIPAAm and PEG. 2013 Young Researchers Pharmaceutics and Biopharmaceutics Meeting, Reading, Aug 2013

Khateb, KA, Lau, WM, Khutoryanskiy, V. Pluronic-based in situ gelling systems for ocular drug delivery (Poster). UK & Ireland Controlled Release Society Symposium, Reading, Apr 2013.

Khateb, KA, Lau, WM, Khutoryanskiy, V. Thermo-reversible in situ gelling systems for ocular drug delivery. Polymeric and Self-Assembled Hydrogels 2012 conference, King's College London, UK. Poster Prize. Sep 2012

Lau, W.M. Examining community pharmacists' role in relation to the use of topical corticosteroids. 1st Pharmacy Practice Research Showcase, Reading, UK. Feb 2013. (invited speaker)

Lau, W.M. et al. Improved topical delivery and skin staining effect of dithranol using the co-drug approach (Poster). Perspectives in Percutaneous Penetration 13th International Conference, France. Apr 2012

Sakenyte, K and Lau, W.M. Skin enzymes facilitated pro-drug and co-drug hydrolysis - implications for topical drug delivery. 69th BPSA Annual Conference, Portsmouth, UK. Apr 2011.

PhD opportunities (self-funded):

A number of opportunities are currently available for self-funded PhD students to undertake research in the areas of:

Topical and transdermal drug delivery

Vaccine design and formulation

Infectious diseases diagnosis and treatment

Safety and efficacy of traditional and herbal medicines

If you are interested in the above areas and would like to discuss the possibility to join our research group as a PhD student, please contact Dr Wing Man Lau for an informal discussion.

Contact Details

Food and Nutritional Sciences 1.05c

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