Funded by: |
Publications
Khanna, S; Dash PR & Darbre PD (2014) "Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro" Journal of Applied Toxicology doi 10.1002/jat.3003
Dannoura A, Giraldo A, Pereira I, Gibbins JM, Dash PR, Bicknell K & Brooks G (2014) "Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: Role of PPARγ" Journal of Pharmacy and Pharmacology. doi: 10.1111/jphp.12203
Collins-Hooper H, Sartori R, Macharia R, Visanuvimol K, Foster K, Matsakas A, Flasskamp H, Ray S, Dash PR, Sandri M, Patel K. (2014) "Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice."J Gerontol A Biol Sci Med Sci 69(9):1049-59
Hooper CL, Paudyal A, Dash PR and Boateng SY (2013) "Modulation of stretch-induced myocyte remodeling and gene expression by nitric oxide: a novel role for lipoma preferred partner in myofibrillogenesis." Am J Physiol Heart Circ Physiol. 2013 May 15;304(10):H1302-13
T.B. Taylor, L.J. Johnson, R.W. Jackson, M.A. Brockhurst and P.R. Dash (2013) "First steps in experimental cancer evolution" Evolutionary Applications 6:535-48
Hooper C, Dash PR and Boateng S (2012) "Lipoma Preferred Partner is a nitric oxide dependent mechanosensitive protein in the heart" FEBS Open Bio. 2:135-144.
Collins-Hooper H, Woolley TE, Dyson L, Patel A, Potter P, Baker RE, Gaffney EA, Maini PK, Dash PR and Patel K (2012) "Age related changes in speed and mechanism of adult skeletal muscle stem cell migration" Stem Cells 30(6): 1182-1195.
Patel A and Dash PR (2012) "Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation" Eur.J.Cell.Biol. 91: 171-179. *Selected by the Faculty of 1000
Otto A, Collins-Hooper H, Patel A, Dash PR and Patel K (2011) "Adult skeletal muscle stem cell migration is mediated by a blebbing / amoeboid mechanism" Rejuvenation Research 14: 249-260
Arias MA, Loxley A, Eatmon C, Van Roey G, Fairhurst D, Mitchnick M, Dash P, Cole T, Wegmann F, Sattentau Q, Shattock R. (2011) "Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen." Vaccine 29:1259-69
Bommer UA, Heng C, Perrin A, Dash P, Lobov S, Elia A and Clemens MJ (2010) "Roles of the translationally controlled tumour protein (TCTP) and the double stranded RNA-dependent protein kinase PKR in cellular stress responses" Oncogene 29, 763–773
Harris LK, McCormick J, Cartwright JE, Whitley GS & Dash PR (2008) "S-nitrosylation of proteins at the leading edge of migrating trophoblasts by inducible nitric oxide synthase promotes trophoblast invasion" Exp.Cell.Res 314: 1765-1776
LaMarca HL, Dash PR, Vishnuthevan K, Harvey E, Sullivan DE, Morris CA & Whitley GStJ (2008) “EGF -stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 MAP Kinase.” Hum. Rep. 23(8):1733-41
Dash PR, McCormick J, Thomson MJ, Johnstone AP, Cartwright JE & Whitley GS (2007) "Fas ligand-induced apoptosis is regulated by nitric oxide through the inhibition of fas receptor clustering and the nitrosylation of protein kinase C epsilon" Exp.Cell Res. 313(16):3421-31
Ganapathy R, Whitley GS, Cartwright JE, Dash PR, Thilaganathan B (2007) "Effect of heparin and fractionated heparin on trophoblast invasion" Hum.Rep. 22(9):2523-7
Whitley GStJ, Dash PR, Ayling LJ, Prefumo F, Thilaganathan B & Cartwright JE (2007) “First Trimester Extravillous Trophoblasts from Pregnancies at Risk of Developing Preeclampsia are More Sensitive to Apoptotic Stimuli” Am.J.Path. 170(6):1903-9
Wong MCY, Portmann B, Sherwood R, Niemela O, Koivisto H, Parkkila S, Trick K, L’Abbe MR, Wilson J, Dash PR, Srirajaskanthan R, Preedy VR & Wiseman H (2007) “The cytoprotective effect of alpha-tocopherol and daidzein against D-galactosamine-induced oxidative damage in the rat liver” Metabolism Jul;56(7):865-75
Dash PR, Whitley GS, Ayling LJ, Johnstone AP & Cartwright JE (2005) “Trophoblast apoptosis is inhibited by hepatocyte growth factor through the AKT and beta-catenin mediated up-regulation of inducible nitric oxide synthase” Cell.Signal. 17(5): 571-80
Ashton SV, Whitley GS, Dash PR, Wareing M, Crocker IP, Baker PN & Cartwright JE (2005) “Uterine spiral artery remodelling involved endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions” Arterioscler. Thromb. Vasc. Biol. 25 (1): 102-108
Dash PR, Cartwright JE, Baker PN, Johnstone AP & Whitley GS (2003) “Nitric oxide protects human extravillous trophoblast cells from apoptosis by a cyclic GMP-dependent mechanism and independently of caaspse 3 nitrosylation” Exp.Cell.Res 287 (2): 314-324
Dash PR, Cartwright JE & Whitley GS (2003) “Nitric oxide inhibits polyamine-induced apoptosis in the human extravillous trophoblast cell line SGHPL-4” Hum.Reprod. 18(5): 959-68
J.E. Cartwright, L.C. Kenny, P.R. Dash, I.P. Crocker, J.D. Aplin, P.N. Baker and G.StJ. Whitley (2001) “Trophoblast invasion of spiral arteries: a novel in vitro model.” Placenta 23: 232-235
Parker, A.L.; Oupicky, D.; Dash, P.R. & Seymour, L.W. (2001) “Methodologies for monitoring nanoparticle formation by self-assembly of DNA with poly(L-lysine)” Anal.Biochem. 302: 75-80
Oupicky, D.; Ogris, M.; White, S.; Ward, C.M.; Howard, K.A.; Dash, P.R. & Seymour, L.W. (2001) “Importance of lateral stabilisation of polyelectrolyte gene delivery vectors for extended systemic circulation and accumulation in subcutaneous tumours” Molecular Therapy 5: 463-472
Dash, P.R.; Read, M.; Fisher, K.; Oupicky, D.; Nazarova, O.; Ulbrich, K. & Seymour, L.W. (2000) “Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer
and Retargeting through Attachment of Transferrin” J.Biol.Chem 275 (6): 3793-3802
Howard, K. A.; Dash, P. R.; Read, M. L.; Ward, C.; Tomkins, L. M.; Nazarova, O.; Ulbrich, K. & Seymour, L. W. (2000) “Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA” Biochim. Biophys. Acta- Gen. Subjects 1475 (3): 245-255
Read, M.L.; Dash, P.R.; Clark, A.; Howard, K.A.; Oupicky, D.; Toncheva, V.; Alpar, H.O.; Schacht, E.H.; Ulbrich, K. and Seymour, L.W. (2000) “Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers” Eu.J.Pharm.Sci 10 (3):169-177
Oupicky, D.; Howard, K.A.; Konak, C.; Dash, P.R.; Ulbrich, K, & Seymour, L.W. (2000) “Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly N-(2-hydroxypropyl)methacrylamide.” Bioconjugate Chem. 11: 492-501
Dash, P.R.; Read, M.; Barret, L.B. & L.W.Seymour (1999) “Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery” Gene Therapy 6: 643-650
Wolfert, M.A.; Dash, P.R.; Oupicky, D.; Smart, S.; Nazarova, O.; Ulbrich, K. & Seymour, L.W. (1999) “Comparison of the biophysical properties of polymer-based vectors for gene therapy formed using a variety of cationic polymers” Bioconjugate Chem. 10: 993-1004
Oupicky, D.; Konak, C.; Dash, P.R.; Seymour, L.W. and Ulbrich, K. (1999) “Effect of Albumin and polyanion on the structure of DNA complexes with polycation containing a hydrophilic nonionic block” Bioconjugate Chem. 10: 764-772
Toncheva, V.; Wolfert, M.A.; Dash, P.R.; Oupicky, D.; Ulbrich, K.; Seymour, L.W. & Schacht, E.H. (1998) “Novel Vectors for Gene Delivery Formed by Self-Assembly of DNA with Poly(L-lysine) Grafted with Hydrophilic Polymers” Biochim.Biophys.Acta 1380: 354-368
Dash, P.R.; Toncheva, V.; Schacht, E. & Seymour, L.W. (1997) “Synthetic Polymers for vectorial Delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy, stability to nuclease degradation and disruption by polyanions in vitro” J.Controlled Release 48: 269-276