Dr Louise Johnson
Responsibilities
Lecturer
- Admissions Tutor for BSc Zoology
Member of:
- School Athena SWAN Committee
- University-wide committee to promote undergraduate research
Areas of Interest
- Experimental evolution of the genetic code
- Multilevel selection in cancer and intragenomic conflicts
- Evolution of genetic systems, particularly breeding systems
- Funding from NERC and the Leverhulme Trust
Member of the Evolution Research Group
Impact, Enterprise and Outreach
- Involved in outreach events to schools and the public including the Wellcome-funded "I'm a Scientist" and L'Oreal / ZSL "Soap Box Science"
- Contributor to "The Open Laboratory" popular science anthology
Esteem Factors
- Member of Steering Committee of NERC Biomolecular Analysis Facility
- Editorial Board, Journal of Evolutionary Biology and Mobile Genetic Elements
- Plenary Speaker, "Genomic Consequences of Unconventional Sex", University of Cape Town
Teaching
- Part 1: Genes and Chromosomes, Pathology: Introduction to Human Disease, Exploiters and Exploited
- Part 2: Evolutionary Biology, Animal, Plant and Microbial Development
- Part 3: Evolutionary Genetics and Phylogeny, Seminars in Biology , Mechanisms for Microbial Function, Research Project Supervision
International Collaborators
- Prof. Paul Rainey FRSNZ, New Zealand Institute of Advanced Study and Max Planck Institute for Evolutionary Biology, New Zealand
- Prof. James Cook, University of Western Sydney, Australia
- Dr Tek Tay, CSIRO, Australia
National Collaborators
- Prof. Michael Brockhurst, University of York
- Prof. Richard Nichols, Queen Mary University, London
- Dr. James Cotton, Sanger Centre, Cambridge
- Dr. Steve Le Comber, Queen Mary University, London
Research groups / Centres
Publications
2020
-
Butler, G., Keeton, S. J., Johnson, L. J.
ORCID: https://orcid.org/0000-0002-0006-1511 and Dash, P. R. (2020) A phenotypic switch in the dispersal strategy of breast cancer cells selected for metastatic colonization. Proceedings of the Royal Society B: Biological Sciences, 287 (1940). ISSN 0962-8452 doi: https://doi.org/10.1098/rspb.2020.2523
- Cascant-Lopez, E., Crosthwaite, S. K., Johnson, L. J. and Harrison, R. J. (2020) No evidence that homologs of key circadian clock genes direct circadian programs of development or mRNA abundance in Verticillium dahliae. Frontiers in Microbiology, 11 (1977). ISSN 1664-302X doi: https://doi.org/10.3389/fmicb.2020.01977
- Wass, A. V., Butler, G., Taylor, T. B., Dash, P. R. and Johnson, L. J. (2020) Cancer cell lines show high heritability for motility but not generation time. Royal Society Open Science, 7 (4). 191645. ISSN 2054-5703 doi: https://doi.org/10.1098/rsos.191645
2017
- Taylor, T. B., Wass, A. V., Johnson, L. J. and Dash, P. (2017) Resource competition promotes tumour expansion in experimentally evolved cancer. BMC Evolutionary Biology, 17. 268. ISSN 1471-2148 doi: https://doi.org/10.1186/s12862-017-1117-6
2015
- Taylor, T., Mulley, G., McGuffin, L., Johnson, L., Brockhurst, M., Arseneault, T., Silby, M. and Jackson, R. (2015) Evolutionary rewiring of bacterial regulatory networks. Microbial Cell, 2 (7). pp. 256-258. ISSN 2311-2638 doi: https://doi.org/10.15698/mic2015.07.215
- Taylor, T. B., Mulley, G., Dills, A. H., Alsohim, A. S., McGuffin, L. J., Studholme, D. J., Silby, M. W., Brockhurst, M. A., Johnson, L. J. and Jackson, R. W. (2015) Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system. Science, 347 (6225). pp. 1014-1017. ISSN 0036-8075 doi: https://doi.org/10.1126/science.1259145
2014
- Alsohim, A. S., Taylor, T., Barrett, G., Gallie, J., Zhang, X.-X., Altamirano-Junqueira, A. E., Johnson, L., Rainey, P. B. and Jackson, R. (2014) The biosurfactant viscosin produced by Pseudomonas fluorescens SBW25 aids spreading motility and plant growth promotion. Environmental Microbiology, 16 (7). pp. 2267-2281. ISSN 1462-2920 doi: https://doi.org/10.1111/1462-2920.12469
2013
- Taylor, T. B., Johnson, L. J., Jackson, R. W., Brockhurst, M. A. and Dash, P. R. (2013) First steps in experimental cancer evolution. Evolutionary Applications, 6 (3). pp. 535-548. ISSN 1752-4571 doi: https://doi.org/10.1111/eva.12041
2011
- Jackson, R. W., Johnson, L. J., Clarke, S. R. and Arnold, D. L. (2011) Bacterial pathogen evolution: breaking news. Trends in Genetics, 27 (1). pp. 32-40. ISSN 0168-9525 doi: https://doi.org/10.1016/j.tig.2010.10.001
- Johnson, L. J., Cotton, J. A., Lichtenstein, C. P., Elgar, G. S., Nichols, R. A., Polly, P. D. and Le Comber, S. C. (2011) Stops making sense: translational trade-offs and stop codon reassignment. BMC Evolutionary Biology, 11 (1). 227. ISSN 1471-2148 doi: https://doi.org/10.1186/1471-2148-11-227
2010
- Johnson, L. J. (2010) Pseudogene rescue: an adaptive mechanism of codon reassignment. Journal of Evolutionary Biology, 23 (8). pp. 1623-1630. ISSN 1010-061X doi: https://doi.org/10.1111/j.1420-9101.2010.02027.x
- Johnson, L. J. and Tricker, P. J. (2010) Epigenomic plasticity within populations: its evolutionary significance and potential. Heredity, 105 (1). pp. 113-121. ISSN 0018-067X doi: https://doi.org/10.1038/hdy.2010.25
- Johnson, L. J., Giraud, T., Anderson, R. and Hood, M. E. (2010) The impact of genome defense on mobile elements in Microbotryum. Genetica, 138 (3). pp. 313-319. ISSN 1573-6857 doi: https://doi.org/10.1007/s10709-009-9419-2
2008
- Johnson, L. J. (2008) Selfish genetic elements favor the evolution of a distinction between soma and germline. Evolution, 62 (8). pp. 2122-2124. ISSN 0014-3820 doi: https://doi.org/10.1111/j.1558-5646.2008.00433.x
- Johnson, L. (2008) Transposon silencing: the extraordinary epigenetics of a transposon trap. Heredity, 100 (1). p. 5. ISSN 1365-2540 doi: https://doi.org/10.1038/sj.hdy.6801064
2007
- Antonovics, J., Abbate, J. L., Baker, C. H., Daley, D., Hood, M. E., Jenkins, C. E., Johnson, L. J., Murray, J. J., Panjeti, V., Rudolf, V. H., Sloan, D. and Vondrasek, J. (2007) Evolution by any other name: antibiotic resistance and avoidance of the E-word. PLoS Biology, 5 (2). e30. ISSN 1544-9173
- Johnson, L. J. (2007) The genome strikes back: The evolutionary importance of defence against mobile elements. Evolutionary Biology, 34 (3-4). pp. 121-129. ISSN 0071-3260 doi: https://doi.org/10.1007/s11692-007-9012-5
2006
- Brookfield, J. F. and Johnson, L. J. (2006) The evolution of mobile DNAs: when will transposons create phylogenies that look as if there is a master gene? Genetics, 173 (2). pp. 1115-23. ISSN 0016-6731 doi: https://doi.org/10.1534/genetics.104.027219
- Johnson, L. J. and Brookfield, J. F. (2006) A test of the master gene hypothesis for interspersed repetitive DNA sequences. Molecular Biology and Evolution, 23 (2). pp. 235-9. ISSN 0737-4038 doi: https://doi.org/10.1093/molbev/msj034
Pre 2006
L.J. Johnson, J. Antonovics and M. E. Hood. The evolution of intratetrad mating rates. Evolution 59: 2525-2532 (2005).
L. J. Johnson, V. Koufopanou, M. R. Goddard, R. Hetherington, S Schaeffer and A. Burt. Population genetics of the wild yeast Saccharomyces paradoxus. Genetics 166: 43-52 (2004).
L. J. Johnson and J. F. Y. Brookfield. Evolution of spatial expression pattern. Evolution and Development 5: 593-599 (2003).
L. J. Johnson and J. F. Y. Brookfield. Evolutionary dynamics of a selfishly spreading gene that stimulates sexual reproduction in a partially sexual population. Journal of Evolutionary Biology 15: 42-48 (2002).