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Sheila MacIntyre

Portrait of Sheila Macintyre

Programme advisor for Microbiology


 

Areas of interest

  • Cell surfaces of Gram negative bacteria
  • Secretion via the chaperone: usher pathway
  • Assembly of surface F1 antigen of the plague pathogen, Yersinia pestis
  • Secretion of proteins by fish pathogens belonging to Aeromonas spp
  • Genomics of rodent associated Campylobacter

Teaching

  • Part 1: Introductory Microbiology
  • Part 2: Microbiology- a medical perspective; Medical microbiology (Pharmacy); Function of the Bacterial Cell
  • Part 3: Bacterial pathogens; Use and abuse of the Microbial world

Research centres and groups

Microbiome and Iron Research Group

International Collaborators

  • Professor Stefan Knight, Swedish University of Agricultural Sciences, Uppsala, Sweden
  • Dr Anton Zavialov, SUAS, Uppsala and University of Turku, Finland

National Collaborators

  • Professor Martin Maiden , Dept Zoology, Oxford University
  • Dr Noel MacCarthy, Oxford University /PHE Didcot
  • Professor Haroun Shah, PHE Microbiology services, Colindale, London

Background

Member of the Microbiology Research Group

Selected publications

Kersley, J., Zavialov, A. V., Moslehi, E. , Knight, S. D. and MacIntyre, S. (2003) Mutagenesis elucidates the assembly pathway and structure of Yersinia pestis F1 polymer Adv Exp Med Biol 529: 113-116

Zavialov, A.V. Kersley, J., Korpela, T., Zav'yalov, V.P., MacIntyre, S. and Knight, S. (2002) Donor strand complementation mechanism in the biogenesis of non-pilus system. Mol. Microbiol45, 983-995

MacIntyre, S., Zyrianova, I.M., Chernovskaya, T.V., Leonard, M., Rudenko,E.G., Zav'yalov, V.P. and Chapman, D.A.G. (2001) An extended hydrophobic interactive surface of Yersinia pestis Caf1M chaperone is essential for subunit binding and F1 capsule assembly Mol. Microbiol39, 12-25.

Publications

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