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Dr Dyan Sellayah – University of Reading

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Dr Dyan Sellayah

Dr Dyan Sellayah
Job Title:
Lecturer in Cellular and Organismal Metabolism
Dyan Sellayah



  • Module convenor for BI3BA7-Medical Genetics (year 3), BI3EM1-Evolutionary Medicine (year 3)
  • Admissions Tutor & Program Director for Medical Sciences

Areas of Interest

Dr. Sellayah's research aims to investigate the molecular mechanisms that govern fat (adipose) tissue development and function in the context of obesity. His specific focus is in:

  • Investigating the developmental programming of brown adipose tissue thermogenesis.
  • Assessing the Impact of maternal nutrition during development on offspring adipose tissue development and function.
  • Elucidating the function of FTO in adipogenesis
  • Establishing the therapeutic potential of metformin's effects on adipose tissue
  • Evolutionary origins of obesity

Impact, Enterprise and Outreach

  • School Director for Outreach
  • Project co-founder of ReadiLab Initiative
  • Contributor to Reading Scholars' Program

Esteem Factors

  • Recipient of the MRC New Investigator Research Grant award (2017) of £409,989
  • Junior Research Fellow, Linacre College, University of Oxford 2014-2015
  • Paper selected in top 5 basic research articles of 2014 in the journal Endocrinology
  • Research highlight, Nature Medicine:17:1356, 2011


  • Part 3: Medical Genetics

National Collaborators

  • Prof Roger Cox (MRC Harwell)
  • Dr Felino Cagampang (University of Southampton)
  • Prof Dame Frances Ashcroft (University of Oxford)

Research groups / Centres


Jump to: 2020 | 2019 | 2018 | 2015 | 2014
Number of items: 11.






This list was generated on Sat Jan 23 20:44:07 2021 UTC.


Sellayah D, Sikder D. Feeding the heat on brown fat. Annals of the New York Academy of Sciences 2013: 1302(1):11-23.

Sellayah D, Sikder D. Food for thought: Understanding the multifaceted nature of orexins. Endocrinology 2013: 154(11):3990-9.


Sellayah D, Sikder D. Orexin receptor-1 mediates brown fat developmental differentiation. Adipocyte 2012: 1:58-63.


Sellayah D, Bharaj P, Sikder D. Orexin is required for brown adipose tissue development, differentiation and function. Cell Metabolism 2011: 14:478-490.


Sellayah D, Sek K, Anthony FW, Hanson MA, Cagampang FR. Sensitivity of housekeeping genes in the hypothalamus to mismatch in diets between pre- and postnatal periods in mice. Neuroscience Letters 2008: 447(1):54-57.

Sellayah D, Sek K, Anthony FW, Watkins AJ, Osmond C, Fleming TP, Hanson MA, Cagampang FR. Appetite regulatory mechanisms and food intake in mice are sensitive to mismatch in diets between pregnancy and postnatal periods. Brain Research 2008: 1237:146-152.

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