The Psychopathology & Affective Neuroscience (PAN) Research Division incorporates psychological and neuroscientific approaches to the study of emotion-relevant processes in clinical and non-clinical populations. Our guiding principle is to ensure that our research yields health benefits across the lifespan, from infancy to old age.
We have internationally recognised strengths in development of emotion and psychopathology, treatment of psychopathology, emotion regulation, and the brain, bodily and genetic mechanisms of social cognition and emotional order and disorder.
With a focus on translational research, we are dedicated to advancing understanding of the underlying causes and effective treatment of depression, anxiety, psychosis, eating disorders and autism in children and younger adults, as well as neurodegeneration and wellbeing in older adults.
Our team includes founders of the Winnicott Research Unit, the Charlie Waller Institute of Evidence Based Psychological Treatments, the Anxiety and Depression in Young People (AnDY) research clinic, the Centre for Autism and the Centre for Integrative Neuroscience and Neurodynamics.
The Division's research strength is unique in the UK and researchers within PAN are strongly interconnected, as evidenced by joint research grants and projects, co-supervision of PhD students funded by internal and external grants – including an MRC Doctoral Training Grant – and the organisation of events and meetings such as the annual Reading Emotions symposia.
Our researchers’ expertise has also benefited wider society through the publication of books, including Professor Lynne Murray’s The Psychology of Babies and Professor Shirley Reynolds and Dr Monika Parkinson's Am I Depressed And What Can I Do About It?. The latter, a self-help guide for teenagers, has been selected as part of the Books on Prescription scheme and will be held in all libraries.
The findings of a study led by PAN researchers are breaking new ground in the delivery of interventions to improve cognitive and language development in children in low and middle income countries
Working alongside colleagues from South Africa’s Stellenbosch University, Professors Peter Cooper and Lynne Murray showed that their programme to enhance the book-sharing skills of carers of young children led to significant improvements in infants’ attention and language skills.
The success of this research, which was carried out in Khayelitsha, Cape Town, has inspired a larger scale study in Lesotho. Further research is currently underway or planned in South Africa, El Salvador, Brazil, and America.
Peter Cooper and Lynne Murray have set up a charity, www.mikhulutrust.org, to facilitate the dissemination of the training materials developed in the course of this work.
In an absolute state: elevated use of absolutist words is a marker specific to anxiety, depression and suicidal ideation. Clinical Psychological Science. ISSN 2167-7034 - DOI
Navigating the development and dissemination of internet cognitive behavioral therapy (iCBT) for anxiety disorders in children and young people: a consensus statement with recommendations from the #iCBTLorentz Workshop Group. Internet Interventions. ISSN 2214-7829- DOI (In Press)
Intolerance of uncertainty, anxiety and worry in children and adolescents: a meta-analysis. Journal of Affective Disorders, 225. pp. 80-90. ISSN 0165-0327 - DOI
Brief Behavioural Activation treatment for depressed adolescents delivered by non-specialist clinicians: a case illustration. Cognitive and Behavioral Practice, 25 (2). pp. 208-224. ISSN 1077-7229 - DOI
Aging is associated with a prefrontal lateral-medial shift during picture-induced negative affect. Social Cognitive and Affective Neuroscience, 13 (2). pp. 156-163. ISSN 1749-5024 - DOI
Reduced reward-related neural response to mimicry in individuals with autism. The European Journal of Neuroscience, 47 (6). pp. 610-618. ISSN 0953-816X - DOI
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Reading Emotions Symposium, 12-13 June 2018