Dr Anastasia Christakou
Responsibilities
Teaching
Part 1 and Part 3; MSc; PhD
Qualifications
BSc Biology, Imperial College London
PhD Behavioural Neuroscience, University of Cambridge
Areas of Interest
Learning and decision-making; development; cognition/emotion interactions; neurochemistry; molecules-to-mind approaches in neuroscience
Research groups / Centres
CINN; Psychopathology and Affective Neuroscience; Adolescence; Lifespan Development
Publications
Y
Number of items: 33.
2018
- Reader, A. T., Rao, V. M., Christakou, A. and Holmes, N. P. (2018) A kinematic examination of dual-route processing for action imitation. Attention, Perception, & Psychophysics. ISSN 1943-393X doi: https://doi.org/10.3758/s13414-018-1582-z
- Bell, T., Lindner, M., Mullins, P. G. and Christakou, A. (2018) Functional neurochemical imaging of the human striatal cholinergic system during reversal learning. The European Journal of Neuroscience, 47 (10). pp. 1184-1193. ISSN 0953-816X doi: https://doi.org/10.1111/ejn.13803
- Norman, L. J., Carlisi, C. O., Christakou, A., Murphy, C. M., Chantiluke, K., Giampietro, V., Simmons, A., Brammer, M., Mataix-Cols, D. and Rubia, K. (2018) Fronto-striatal dysfunction during decision-making in Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022 doi: https://doi.org/10.1016/j.bpsc.2018.03.009 (In Press)
- O’Connell, G., Hsu, C.-T., Christakou, A. and Chakrabarti, B. (2018) Thinking about others and the future: neural correlates of perspective taking relate to preferences for delayed rewards. Cognitive, Affective, & Behavioral Neuroscience, 18 (1). pp. 35-42. ISSN 1531-135X doi: https://doi.org/10.3758/s13415-017-0550-8
2017
- Carlisi, C. O., Norman, L. J., Murphy, C. M., Christakou, A., Chantiluke, K., Giampietro, V., Simmons, A., Brammer, M., Murphy, D. M., Mataix-Cols, D., Rubia, K. and MRC AIMS consortium, (2017) Shared and disorder-specific neurocomputational mechanisms of decision-making in Autism Spectrum Disorder and Obsessive-Compulsive Disorder. Cerebral Cortex, 27 (12). pp. 5804-5816. ISSN 1460-2199 doi: https://doi.org/10.1093/cercor/bhx265
- Norman, L. J., Carlisi, C. O., Christakou, A., Chantiluke, K., Murphy, C., Simmons, A., Giampietro, V., Brammer, M., Mataix-Cols, D. and Rubia, K. (2017) Neural dysfunction during temporal discounting in paediatric Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder. Psychiatry Research: Neuroimaging, 269. pp. 97-105. ISSN 0925-4927 doi: https://doi.org/10.1016/j.pscychresns.2017.09.008
- Murphy, C. M., Christakou, A., Giampietro, V., Brammer, M., Daly, E. M., Ecker, C., Johnston, P., Spain, D., Robertson, D. M., MRC AIMS, C., Murphy, D. G. and Rubia, K. (2017) Abnormal functional activation and maturation of ventromedial prefrontal cortex and cerebellum during temporal discounting in autism spectrum disorder. Human Brain Mapping, 38 (11). pp. 5343-5355. ISSN 1065-9471 doi: https://doi.org/10.1002/hbm.23718
- Carlisi, C. O., Norman, L., Murphy, C. M., Christakou, A., Chantiluke, K., Giampietro, V., Simmons, A., Brammer, M., Murphy, D. G., Mataix-Cols, D. and Rubia, K. (2017) Comparison of neural substrates of temporal discounting between youth with Autism Spectrum Disorder and with Obsessive-Compulsive Disorder. Psychological Medicine, 47 (14). pp. 2513-2527. ISSN 1469-8978 doi: https://doi.org/10.1017/S0033291717001088
- Lindner, M., Bell, T., Iqbal, S., Mullins, P. G. and Christakou, A. (2017) In vivo functional neurochemistry of human cortical cholinergic function during visuospatial attention. PLoS ONE, 12 (2). e0171338. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0171338
- Norman, L. J., Carlisi, C. O., Christakou, A., Cubillo, A., Murphy, C. M., Chantiluke, K., Simmons, A., Giampietro, V., Brammer, M., Mataix-Cols, D. and Rubia, K. (2017) Shared and disorder-specific task-positive and default mode network dysfunctions during sustained attention in paediatric Attention-Deficit/Hyperactivity Disorder and obsessive/compulsive disorder. NeuroImage: Clinical, 15. pp. 181-193. ISSN 2213-1582 doi: https://doi.org/10.1016/j.nicl.2017.04.013
2016
- Carlisi, C. O., Norman, L., Murphy, C. M., Christakou, A., Chantiluke, K., Giampietro, V., Simmons, A., Brammer, M., Murphy, D. G., MRC, A. C., Mataix-Cols, D. and Rubia, K. (2016) Disorder-specific and shared brain abnormalities during vigilance in autism and obsessive-compulsive disorder. Biological Psychiatry. ISSN 0006-3223 doi: https://doi.org/10.1016/j.bpsc.2016.12.005
- Morriss, J., Christakou, A. and Van Reekum, C. M. (2016) Nothing is safe: intolerance of uncertainty is associated with compromised fear extinction learning. Biological Psychology, 121. pp. 187-193. ISSN 0301-0511 doi: https://doi.org/10.1016/j.biopsycho.2016.05.001 (Part B)
- Carlisi, C. O., Chantiluke, K., Norman, L., Christakou, A., Barrett, N., Giampietro, V., Brammer, M., Simmons, A. and Rubia, K. (2016) The effects of acute fluoxetine administration on temporal discounting in youth with ADHD. Psychological Medicine, 46 (6). pp. 1197-1209. ISSN 0033-2917 doi: https://doi.org/10.1017/S0033291715002731
2015
- Morriss, J., Christakou, A. and Van Reekum, C. M. (2015) Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry. Biology of Mood & Anxiety Disorders, 5 (1). 4. ISSN 2045-5380 doi: https://doi.org/10.1186/s13587-015-0019-8
- O'Connell, G., Christakou, A. and Chakrabarti, B. (2015) The role of simulation in intertemporal choices. Frontiers in Neuroscience, 9. 94. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2015.00094
2014
- Christakou, A. (2014) Present simple and continuous: emergence of self-regulation and contextual sophistication in adolescent decision-making. Neuropsychologia, 65. pp. 302-312. ISSN 0028-3932 doi: https://doi.org/10.1016/j.neuropsychologia.2014.09.008
- Murphy, C. M., Christakou, A., Daly, E. M., Ecker, C., Giampetro, V., Brammer, M., Smith, A. B., Johnston, P., Robertson, D. M., Murphy, D. G. and Rubia, K. (2014) Abnormal functional activation and maturation of fronto-striato-temporal and cerebellar regions during sustained attention in autism spectrum disorder. American Journal of Psychiatry, 171 (10). pp. 1107-1116. ISSN 0002-953X doi: https://doi.org/10.1176/appi.ajp.2014.12030352
- Chantiluke, K., Christakou, A., Murphy, C. M., Giampietro, V., Daly, E. M., Ecker, C., Brammer, M., Murphy, D. G. and Rubia, K. (2014) Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and Autism. Psychiatry Research: Neuroimaging, 223 (2). pp. 113-120. ISSN 0925-4927 doi: https://doi.org/10.1016/j.pscychresns.2014.04.006
2013
- Christakou, A., Gershman, S., Niv, Y., Simmons, A., Brammer, M. and Rubia, K. (2013) Neural and psychological maturation of decision-making in adolescence and young adulthood. Journal of Cognitive Neuroscience, 25 (11). pp. 1807-1823. ISSN 1530-8898 doi: https://doi.org/10.1162/jocn_a_00447
- O'Connell, G., Christakou, A., Haffey, A. J. and Chakrabarti, B. (2013) The role of empathy in choosing rewards from another's perspective. Frontiers in Human Neuroscience, 7. Article 174. ISSN 1662-5161 doi: https://doi.org/10.3389/fnhum.2013.00174
- Christakou, A., Murphy, C., Chantiluke, K., Cubillo, A., Smith, A., Giampietro, V., Daly, E., Ecker, C., Robertson, D., MRC AIMS Consortium, -, Murphy, D. and Rubia, K. (2013) Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism. Molecular Psychiatry, 18 (2). pp. 236-244. ISSN 1476-5578 doi: https://doi.org/10.1038/mp.2011.185
2011
- Christakou, A., Brammer, M. and Rubia, K. (2011) Maturation of limbic corticostriatal activation and connectivity associated with developmental changes in temporal discounting. NeuroImage, 54 (2). pp. 1344-1354. ISSN 1053-8119 doi: https://doi.org/10.1016/j.neuroimage.2010.08.067
2009
- Christakou, A., Halari, R., Smith, A. B., Ifkovits, E., Brammer, M. and Rubia, K. (2009) Sex-dependent age modulation of frontostriatal and temporo-parietal activation during cognitive control. NeuroImage, 48 (1). pp. 223-236. ISSN 1095-9572 doi: https://doi.org/10.1016/j.neuroimage.2009.06.070
- Christakou, A., Brammer, M., Giampietro, V. and Rubia, K. (2009) Right ventromedial and dorsolateral prefrontal cortices mediate adaptive decisions under ambiguity by integrating choice utility and outcome evaluation. The Journal of Neuroscience , 29 (35). pp. 11020-8. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.1279-09.2009
- Rubia, K., Halari, R., Christakou, A. and Taylor, E. (2009) Impulsiveness as a timing disturbance: neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidate. Philosophical Transactions of the Royal Society B-Biological Sciences, 364 (1525). pp. 1919-31. ISSN 0962-8436 doi: https://doi.org/10.1098/rstb.2009.0014
- Christakou, A., Brammer, M. and Rubia, K. (2009) Maturation of limbic corticostriatal activation and connectivity associated with developmental changes in temporal discounting. In: British Association for Cognitive Neuroscience Conference and Annual Meeting , London, UK.
- Murphy, C., Christakou, A., Daly, E., Johnston, P., Spain, D., Murphy, D.G. and Rubia, K. (2009) fMRI investigation of sustained attention and sensorimotor synchronisation in children and adolescents with autistic spectrum disorder. In: 8th Annual International Society Meeting for Autism Research, Chicago, USA.
2007
- Baunez, C., Christakou, A., Chudasama, Y., Forni, C. and Robbins, T. W. (2007) Bilateral high-frequency stimulation of the subthalamic nucleus on attentional performance: transient deleterious effects and enhanced motivation in both intact and parkinsonian rats. The European Journal of Neuroscience, 25 (4). pp. 1187-1194. ISSN 0953-816X doi: https://doi.org/10.1111/j.1460-9568.2007.05373.x
- Haggard, P., Christakou, A. and Serino, A. (2007) Viewing the body modulates tactile receptive fields. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 180 (1). pp. 187-193. ISSN 0014-4819 doi: https://doi.org/10.1007/s00221-007-0971-7
2005
- Christakou, A., Robbins, T. W. and Everitt, B. J. (2005) Prolonged neglect following unilateral disruption of a prefrontal cortical-dorsal striatal system. The European Journal of Neuroscience, 21 (3). pp. 782-792. ISSN 0953-816X doi: https://doi.org/10.1111/j.1460-9568.2005.03892.x
2004
- Christakou, A., Robbins, T. W. and Everitt, B. J. (2004) Prefrontal cortical-ventral striatal interactions involved in affective modulation of attentional performance: implications for corticostriatal circuit function. The Journal of Neuroscience , 24 (4). pp. 773-780. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.0949-03.2004
2001
- Christakou, A., Robbins, T. W. and Everitt, B. J. (2001) Functional disconnection of a prefrontal cortical-dorsal striatal system disrupts choice reaction time performance: implications for attentional function. Behavioral Neuroscience, 115 (4). pp. 812-25. ISSN 0735-7044 doi: https://doi.org/10.1037/0735-7044.115.4.812
- Christakou, A. (2001) Prefrontal cortico-striatal systems underlying executive attention. PhD thesis, University of Cambridge.
Teaching:
Undergraduate: Learning and Decision-making; Postgraduate: Adolescent Development and Psychopathology, Frontostriatal Mechanisms of Reinforcement, Affective Decision-making, Scientific Writing
Qualifications:
BSc Biology, Imperial College London; PhD Experimental Psychology, Cambridge