Staff Profile:Dr Hisham Al-Obaidi
- Name:
- Dr Hisham Al-Obaidi
- Job Title:
- Lecturer in Pharmaceutics
- Responsibilities:
- Teaching on MPharm Programme and PM3A convener
- Areas of Interest:
Dr Hisham Al-Obaidi is a member of the General Pharmaceutical Council, Royal Pharmaceutical Society and the UK Clinical Pharmacy Association (UKCPA). He completed his BSc in pharmacy from Jordan University of Science and Technology. He then finished his MSc (distinction) and PhD in drug delivery from University College London. After working at King's College London as a research and teaching fellow in pharmacy, he then joined Reading school of Pharmacy in February 2016 as a lecturer in pharmaceutics.
During his research he has developed novel drug delivery carriers such as tertiary-based polymeric solid dispersions and hybrid magnetite nanoparticles for targeted drug delivery. He is particularly interested in engineering amorphous and crystalline materials for drug delivery purposes. These include the use of co-crystals as combination treatments, amorphous solid dispersions for oral drug delivery and encapsulation of bioactives into more complex carriers. Within this context Dr Al-Obaidi has developed substantive experience in thermodynamic models for prediction of drug/carrier miscibility and use of surface-active agents to aid dissolution and improve aqueous solubility. Being a prescribing pharmacist along side previous experience in pharmaceutical industry and community pharmacy his research is originated towards matching scientific research with clinical needs.
- Research groups / Centres:
- Publications:
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YNumber of items: 9.
2020
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Sanduk, F., Meng, Y., Widera, D.
ORCID: https://orcid.org/0000-0003-1686-130X, Kowalczyk, R. M., Michael, N., Kaur, A., Yip, V., Zulu, S., Zavrou, I., Hana, L., Yaqoob, M. and Al-Obaidi, H. (2020) Enhanced anti-inflammatory potential of degradation resistant curcumin/ferulic acid eutectics embedded in triglyceride-based microemulsions. Journal of Drug Delivery Science and Technology, 60. 102067. ISSN 1773-2247 doi: https://doi.org/10.1016/j.jddst.2020.102067
- Patel, N., Zariwala, M. G. and Al-Obaidi, H. (2020) Fabrication of biopolymer based nanoparticles for the entrapment of chromium and iron supplements. Processes, 8 (6). 707. ISSN 2227-9717 doi: https://doi.org/10.3390/pr8060707
- Chen, X., Partheniadis, I., Nikolakakis, I. and Al-Obaidi, H. (2020) Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling. Polymers, 12 (4). 854. ISSN 2073-4360 doi: https://doi.org/10.3390/polym12040854
- Mohammed, A., Zurek, J., Madueke, S., Al-Kassimy, H., Yaqoob, M., Houacine, C., Ferraz, A., Kalgudi, R., Zariwala, M. G., Hawkins, N. and Al-Obaidi, H. (2020) Generation of high dose inhalable effervescent dispersions against Pseudomonas aeruginosa biofilms. Pharmaceutical Research, 37 (8). 150. ISSN 0724-8741 doi: https://doi.org/10.1007/s11095-020-02878-w
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Assi, S., Khan, I., Edwards, A., Osselton, D. and Al-Obaidi, H.
ORCID: https://orcid.org/0000-0001-9735-0303 (2020) On-spot quantification of modafinil in generic medicines purchased from the internet using handheld Fourier transform-infrared, near-infrared and Raman spectroscopy. Journal of Analytical Science and Technology, 11 (1). 35. ISSN 2093-3371 doi: https://doi.org/10.1186/s40543-020-00229-3
2019
- Al-Obaidi, H., Kowalczyk, R. M., Kalgudi, R. and Zariwala, M. G. (2019) Griseofulvin solvate solid dispersions with synergistic effect against fungal biofilms. Colloids and Surfaces B: Biointerfaces, 184. 11540. ISSN 09277765 doi: https://doi.org/10.1016/j.colsurfb.2019.110540
2018
- Al-Obaidi, H., Kalgudi, R. and Gulrez Zariwala, M. (2018) Fabrication of inhaled hybrid silver/ciprofloxacin nanoparticles with synergetic effect against Pseudomonas aeruginosa. European Journal of Pharmaceutics and Biopharmaceutics, 128. pp. 27-35. ISSN 0939-6411 doi: https://doi.org/10.1016/j.ejpb.2018.04.006
2017
- Al-Obaidi, H., Majumder, M. and Bari, F. (2017) Amorphous and crystalline particulates: challenges and perspectives in drug delivery. Current pharmaceutical design, 23 (3). pp. 350-361. ISSN 1873-4286 doi: https://doi.org/10.2174/1381612822666161107162109
2016
- Al-Obaidi, H., Lawrence, M. J. and Buckton, G. (2016) Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions. Journal of Pharmacy and Pharmacology, 68 (11). pp. 1373-1383. ISSN 2042-7158 doi: https://doi.org/10.1111/jphp.12645
H. Al-Obaidi, A.T. Florence, 2015. Nanoparticle delivery and particle diffusion in confined and complex environments, J Drug Del Sci Tech, .
H. Al-Obaidi, M.J. Lawrence, S. Shah, H. Moghul, N. Al-Saden and F. Bari, 2013. Effect of drug-polymer interactions on the aqueous solubility of milled solid dispersions. Int J Pharm 446, 100-105.
H. Al-Obaidi, M. J. Lawrence, N. Al-Saden and P. Ke, 2013. Investigation of griseofulvin and hydroxypropylmethyl cellulose acetate succinate miscibility in ball milled solid dispersions. Int J Pharm 443, 95-102.
P. Wasutrasawat, H. Al-Obaidi, S. Gaisford, M.J. Lawrence, W. Warisnoicharoen, 2013. Drug solubilisation in lipid nanoparticles containing high melting point triglycerides. Eur J Pharm Biopharm.
P. Ke, S. Hasegawa, H. Al-Obaidi and G. Buckton, 2012. Investigation of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersions. Int J Pharm 422, 170-178.
H. Al-Obaidi, P. Ke, S. Brocchini and G. Buckton, 2011. Characterization and stability of ternary solid dispersions with PVP and PHPMA. Int J Pharm 419, 20-27.
H. Al-Obaidi, B. Nasseri and A.T. Florence, 2010. Dynamics of microparticles inside lipid vesicles: movement in confined spaces. J Drug Target 18, 821-830.
H. Al-Obaidi and G. Buckton, 2009. Evaluation of griseofulvin binary and ternary solid dispersions with HPMCAS. AAPS PharmSciTech 10, 1172-1177.
H.P. Jarvie, H. Al-Obaidi, S.M. King, M Bowes, M.J. Lawrence, A.F. Drake, M.A. Green and P.J. Dobson, 2009. Fate of silica nanoparticles in simulated primary wastewater treatment. Enviro Sci Technol 43, 8622-8628.
H.Al-Obaidi, S. Brocchini and G. Buckton, 2009. Anomalous properties of spray dried solid dispersions. J Pharm Sci 98, 4724-4737.
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Sanduk, F., Meng, Y., Widera, D.
Qualifications
BSc Pharmacy (JUST)
MSc Drug delivery (UCL)
PhD Pharmaceutics (UCL)
Diploma in pharmacy (Brighton)
PGCAP (KCL)
IP certificate (Hertfordshire)