CH2OR1-Further Organic Chemistry

Module Provider: Chemistry
Number of credits: 20 [10 ECTS credits]
Terms in which taught: Autumn / Spring / Summer module
Pre-requisites: CH1OR1 Shape, Structure and Reactivity in Organic Chemistry or CH1OR2 Fundamentals of Organic Chemistry and CH1OR4 Further Fundamental Organic Chemistry for Biologists
Non-modular pre-requisites:
Modules excluded:
Current from: 2018/9

Module Convenor: Dr John McKendrick


Type of module:

Summary module description:

To build on the basic concepts of organic chemistry with a more detailed treatment of selected topics.


To build on the basic concepts of organic chemistry with a more detailed treatment of selected topics.

Assessable learning outcomes:

Students who have successfully completed this module will be able to:

  • • Have an appreciation for the utility of the carbonyl group in Organic Chemistry.

  • • Appreciate how structure, shape and reactivity are linked when considering Organic reactions.

  • • Explain how Organic chemists have studied and unravelled the mechanism of Organic reactions.

Additional outcomes:
The tutorial/workshop environment will improve the students’ oral and presentation skills.

Outline content:

Further Carbonyl Chemistry (5 Lectures): Revision of alpha-acidity of carbonyl compounds. The aldol condensation reaction, crossed aldol condensations, Claisen condensation, Dieckmann condensation, the use of 1,3-dicarbonyl compounds, decarboxylation of 1,3-keto-acids, Michael addition reactions, Robinson annelation.

Organometallics (5 Lectures): Methods for forming C-C bonds using organometallic reagents; basic aspects of preparative carbanion chemistry.

Radical Reactions in Synthesis (6 lectures): The properties and use of free radicals in synthesis will be discussed. Areas covered will include radical addition reactions, radical cyclisations. Tandem radical reactions, the acloin reaction and the Birch reduction.

Molecular Rearrangements (5 Lectures): Topics covered will include the Beckmann, pinacol, Curtius, Hofmann, Baeyer-Villiger and Lossen rearrangements and their use for the synthesis of molecules of industrial importance.

Conformational Analysis (5 Lectures): Differences between conformational and configurational isomers; staggered and eclipsed forms of ethane; butane and butane derivatives; elimination reactions; cyclic systems; small, normal, medium and large rings; entropy and enthalpy factors in ring formations; conformational isomerisation in cyclohexane and relationship to reactivity; decalin systems and steroids.

Synthesis of Alicyclic Compounds (5 Lectures): The methods available for the synthesis of small, medium and large carbo- and hetero-cyclic rings will be outlined, with suitable examples.

Physical Aspects of Organic Chemistry (5 lectures): Factors which drive organic reactions: Isotope effects, Hammett Equation, Rate Equations and Organic Thermodynamics.

Brief description of teaching and learning methods:
Approximately three one-hour lectures per week with roughly one tutorial or workshop on related material every two weeks.

Contact hours:
  Autumn Spring Summer
Lectures 10 26
Seminars 1 2 6
Tutorials 2 4
Guided independent study 37 68 44
Total hours by term 50.00 100.00 50.00
Total hours for module 200.00

Summative Assessment Methods:
Method Percentage
Written exam 80
Set exercise 20

Summative assessment- Examinations:

2 Hours

End of year examination covering all material taught in the lectures (80%).


Summative assessment- Coursework and in-class tests:

On-line tests (20%): Students will be required to undertake short Blackboard tests relating to the lecture material.

Formative assessment methods:

Students attend tutorials and workshops on the material covered in this module. Attendance is compulsory at both, failure to attend will play a part in the triggering of the Universities academic non-engagement process. Workshops build on lecture material and encourage students to think about the lecture material in context and apply this knowledge to unseen problems; workshop problems provide good practice for the end of year examination.

Penalties for late submission:
The Module Convener will apply the following penalties for work submitted late:

  • where the piece of work is submitted after the original deadline (or any formally agreed extension to the deadline): 10% of the total marks available for that piece of work will be deducted from the mark for each working day[1] (or part thereof) following the deadline up to a total of five working days;
  • where the piece of work is submitted more than five working days after the original deadline (or any formally agreed extension to the deadline): a mark of zero will be recorded.

  • The University policy statement on penalties for late submission can be found at:
    You are strongly advised to ensure that coursework is submitted by the relevant deadline. You should note that it is advisable to submit work in an unfinished state rather than to fail to submit any work.

    Assessment requirements for a pass:
    A mark of 40% overall

    Reassessment arrangements:

    Reassessment will be held in the August re-sit examination period and will be by examination only, worth 100%.

    Additional Costs (specified where applicable):

    1) Required text books: Organic Chemistry by Clayden, Greeves and Warren, Oxford University Press

    2) Specialist equipment or materials: N/A

    3) Specialist clothing, footwear or headgear: N/A

    4) Printing and binding: Printing Of Notes Using University Printers incurrs the standard per-page charge. All lecture material will be available on Blackboard. Printing should cost around £20 for this course.

    5) Computers and devices with a particular specification: N/A

    6) Travel, accommodation and subsistence: N/A

    Last updated: 20 April 2018


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