Staff Profile:Dr Marcus Tindall

Name::

Position / Job Title:

RCUK Research Fellow in System Biology

Responsibilities:

Areas of Interest:

Dr Tindall's work is focused on developing well informed mathematical models of biological and biomedical processes. Within this broad remit his work is focused in the areas of lipoprotein metabolism, bacterial chemotaxis and tumour growth. The mathematical models developed are deterministic in nature (ordinary differential and partial differential equations), are used to elucidate the importance of mechanisms within the system being studied and to help in directing future experimental work. Models are solved using computational and analytical (asymptotic) techniques and work is carried out in close collaboration with experimental colleagues.

Research groups / Centres:

Vascular function and pathophysiology

Diet composition and cardiovascular disease phenotype

Publications:

• A continuum receptor model of hepatic lipoprotein metabolism. Tindall MJ, Wattis JA, O'Malley BJ, Pickersgill L, Jackson KG. J Theor Biol. 2008 Dec 6. PMID: 19109979
• Overview of mathematical approaches used to model bacterial chemotaxis I: the single cell. Tindall MJ, Porter SL, Maini PK, Gaglia G, Armitage JP. Bull Math Biol. 2008 Aug;70(6):1525-69
• Overview of mathematical approaches used to model bacterial chemotaxis II: bacterial populations. Tindall MJ, Maini PK, Porter SL, Armitage JP. Bull Math Biol. 2008 Aug;70(6):1570-607.
• Modelling the formation of necrotic regions in avascular tumours. Tindall MJ, Please CP, Peddie MJ. Math Biosci. 2008 Jan;211(1):34-55.
• The migration of cells in multicell tumor spheroids. Pettet GJ, Please CP, Tindall MJ, McElwain DL. Bull Math Biol. 2001 Mar;63(2):231-57.A continuum receptor model of hepatic lipoprotein metabolism. Tindall MJ, Wattis JA, O'Malley BJ, Pickersgill L, Jackson KG. J Theor Biol. 2008 Dec 6. PMID: 19109979