Molecular Biology of the Gene: Expression, Function and Analysis

DNA imageGenes occupy centre stage within the biological universe since they dictate the make-up of all living organisms. But how do they work, what controls their activity and how can we study their function? In this module, we consider the molecular details of gene function in both complex eukaryotes and simplistic prokaryotes. In particular, we focus on how genes are controlled and how understanding of gene function can be enhanced by the use of bioinformatic approaches to investigate the molecular databases.

Spring Term


AndrewsSimon_largeProfessor Simon Andrews is the head of the Biomedical Sciences section of the School of Biological Sciences and the module convenor for the Molecular Biology of the Gene module. He is a microbiologist interested in iron regulation in bacteria. In animals (including humans), iron withdrawal is used as a highly-effective defence strategy to inhibit growth of invading microbes within the body. For this reason, pathogens deploy iron-acquisition systems that target body-iron sources. Such host-specific iron-uptake systems are 'virulence factors' that are often required for effective host colonisation and disease progression. Because of the importance of iron acquisition processes to pathogens, much research is directed towards understanding microbial iron transport in the hope of developing effective countermeasures that could be used to combat infection.

staff photoProfessor Ketan Patel is a developmental biologist with a particular interest in the development of skeletal muscle and also in the maintenance of skeletal muscle in adults. He began his career with a BSc Hons in Biochemistry from the University of Kent before gaining a PhD from Imperial College, London. He previously worked at the Royal Veterinary College before joing the University of Reading.




Other lecturers on this module: Professor Simon Andrews, Professor Ketan Patel, Dr Michael Fry, Dr Liam McGuffin, Professor Philippa Darbre

Module convenor: Professor Simon Andrews

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