Cardiovascular biology research group

Red blood cells in a fibrin clot Cardiovascular diseases, which include heart attacks, strokes and heart failure, are the cause of approximately 250,000 deaths each year in the UK alone, with similar incidence rates across Europe, and North America, and are becoming an increasing burden in rapidly developing nations with very large populations. Substantial progress has been made as a result of biomedical research in the last 3 decades that has resulted in a 50% reduction in the death rate in patients who suffer from cardiovascular diseases.

Staff in the School of Biological Sciences form a core component of the Institute for Cardiovascular and Metabolic Research (ICMR). The ICMR is multidisciplinary centre that brings together scientists from a wide range of research fields to work to understand the development of cardiovascular diseases, and the underlying obesity-related metabolic diseases from which they develop.

Further information about the research interests of individual staff members from the School of Biological Sciences working in the area of cardiovascular disease can be found in the table below. Further details on the work of the ICMR can be found on the Institute for Cardiovascular & Metabolic Research website.

Staff		Research Interests
Professor Angela Clerk		Head of cardiovascular research group Cardiac myocyte signalling and gene expression
Dr Sam Boateng		Cardiovascular research, Myocyte mechanosensing, Circadian proteins
Professor Gavin Brooks		Cardiovascular research, Myocardial regeneration
Dr Michael Fry		Cell signalling, PI-3 kinase signalling, Proteomics & kinase signalling, GSK-3 & Wnt signalling in platelets
Professor Jon Gibbins		Cardiovascular research, Cell Biology, Platelets Haemostasis, Thrombosis
Dr David Leake		Cardiovascular research, Atherosclerosis, Oxidised Low Density Lipoprotein
Dr Liam McGuffin		Bioinformatics, Molecular Systems Biology, Prediction of protein structures, functions and interactions
Professor Peter Sugden		Cardiovascular research
Dr Marcus Tindall		Systems biology, Mathematical modelling
Dr Kim Watson		Metabolic enzymes, ABC transporters, Protein crystallography, Computational Biology