Neuroscience Methods

Our neuroscience group has expertise not only in theoretical modelling of brain signals and its functions, but also in designing and conducting biological, physiological and psychological experiments in purposely built laboratories within the School or in collaboration with the Centre for Integrative Neuroscience and Neurodynamics (CINN), at the University of Reading. This enables us to design and conduct neuroscience experiments, in-house, based on hypotheses generated by mathematical models, and the loop is closed when we modify these mathematical models based on experimental evidence.

We use a range of neuroimaging methods and laboratory techniques:

In vitro experimental studies

Neuroscience MethodsA state-of-the-art laboratory, Brain Embodiment Laboratory, was established in 2012. It is located on the ground floor of the School and it currently has over 14 research staff and PhD students.

The laboratory provides excellent research facility to study how neurons communicate with each other by growing cultured neural networks in a dish and measure neural interaction via a multi-electrode array.

In vivo experimental studies

Neuroscience MethodsAn electrophysiological laboratory has been established recently in the School (located in the BioResource Unit) to conduct in vivo experiments to understand the nature of neocortical neural recordings via micro-electrodes and the link between changes in neural activity and the ensuing changes in the regional cerebral blood flow.

One of our research objectives is to provide appropriate interpretations of signals recorded using non-invasive neuroimaging techniques such as the EEG and fMRI.

Human EEG studies

Neuroscience MethodsThere are two human EEG suites, which are part of the BEL facility, located on the ground floor of the School. Many human EEG projects have been conducted ranging from studying visual attention while driving a train, to looking for signatures of phase synchronisation patterns in pairs of subjects performing a mutual tracking task.

Concurrent EEG and fMRI studies

Neuroscience MethodsIn collaboration with the Centre for Integrative Neuroscience and Neurodynamics (CINN) at the University of Reading, we are developing novel methods that make use of the combined information contained in EEG and fMRI signals, when recorded concurrently, to infer more knowledge about the underlying neural mechanisms, than would otherwise be gathered in separate experiments. Our current projects utilising coupled EEG-fMRI include music perception, sensorimotor processing, characterising functional connectivity during semantic and syntactic information processing, and identifying neural correlates to sensory integration via a virtual 3D avatar (phantom limb).

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Professor Slawomir Nasuto

+44 (0)118 378 6701

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