Staff Profile:Dr Graham Luke

Name:
Dr Graham Luke
Job Title:
Technical Head of Teaching and Research Development
Responsibilities:

I am based on the first floor of the Hopkins Building where I manage the microscopy facility and support laboratory workers including undergraduate project students.

I also have a large teaching aspect to my work (I am registered on the PGCAP programme here at Reading). In the past I have been the Module coordinator of a (now discontinued) Marine Biology Field Work Course, and lectured in the Invertebrate Zoology module, and was a tutor in the Science Communication module (now discontinued). At present I am the Module coordinator of two Second year UG Vertebrate Zoology modules, and lecture in the Animal Plant and Microbial Development Module. I also provide demonstrating support in some practical classes.

Areas of Interest:
Research groups / Centres:
Publications:
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This list was generated on Sat Oct 21 17:45:25 2017 BST.

Career History:

After graduating from Leicester University I was employed as a technician within the Psychology Department and then the Department of Pure and Applied Zoology at Reading. I then studied for a PhD within that department as a research assistant investigating the clustering of homeobox genes in the Cephalochordate, Branchiostoma floridae. This was funded by the BBSRC. Following this I was a post-doctoral researcher investigating firstly the evolution and phylogenetics of FOX genes in a variety of invertebrate taxa (Oxford and Reading University) and then the effect on the transcriptomic/proteomic profile of embryonic musculature under treatment with the myogenic factors follistatin and myostatin (here at the University of Reading). Following this I became a technician again.

Publications:

Collins-Hooper, H., et al., Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers. Transl Res, 2011.

Valasek, P., et al., Cellular and molecular investigations into the development of the pectoral girdle. Dev Biol, 2011.

Shimeld, S.M., B. Degnan, and G.N. Luke, Evolutionary genomics of the Fox genes: origin of gene families and the ancestry of gene clusters. Genomics, 2010. 95(5): p. 256-60.

Shimeld, S.M., et al., Clustered Fox genes in lophotrochozoans and the evolution of the bilaterian Fox gene cluster. Dev Biol, 2010. 340(2): p. 234-48.

Otto, A., et al., Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration. J Cell Sci, 2008. 121(Pt 17): p. 2939-50.

Luke, G.N., et al., Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes. J Gen Virol, 2008. 89(Pt 4): p. 1036-42.

Larroux, C., et al., Genesis and expansion of metazoan transcription factor gene classes. Mol Biol Evol, 2008. 25(5): p. 980-96.

Schmidt, C., et al., Expression and regulation of Nkd-1, an intracellular component of Wnt signalling pathway in the chick embryo. Anat Embryol (Berl), 2006. 211(5): p. 525-34.

Osborne, P.W., et al., Identification and characterisation of five novel miniature inverted-repeat transposable elements (MITEs) in amphioxus (Branchiostoma floridae). Int J Biol Sci, 2006. 2(2): p. 54-60.

Mazet, F., G.N. Luke, and S.M. Shimeld, The amphioxus FoxQ1 gene is expressed in the developing endostyle. Gene Expr Patterns, 2005. 5(3): p. 313-5.

Mazet, F., et al., Expression of AmphiCoe, an amphioxus COE/EBF gene, in the developing central nervous system and epidermal sensory neurons. Genesis, 2004. 38(2): p. 58-65.

Luke, G.N., et al., Dispersal of NK homeobox gene clusters in amphioxus and humans. Proc Natl Acad Sci U S A, 2003. 100(9): p. 5292-5.

Luke, G.N. Education, Engineering and Enlightenment; The Three E's. State and Home Education Contrasted. Home School Researcher, Volume 14, No. 4, 2001, p. 13-23.

Luke, G.N. and P.W. Holland, Amphioxus type I keratin cDNA and the evolution of intermediate filament genes. J Exp Zool, 1999. 285(1): p. 50-6.

Patton, S.J., G.N. Luke, and P.W. Holland, Complex history of a chromosomal paralogy region: insights from amphioxus aromatic amino acid hydroxylase genes and insulin-related genes. Mol Biol Evol, 1998. 15(11): p. 1373-80.

Simkiss, K. and G. Luke, Ballistic transfection of avian primordial germ cells in ovo, in Transgenic Animals: Generation and Use, L.M. Houdebine, Editor. 1997, Harwood Academic: Amsterdam ; Great Britain. p. xxii, 576p.

Simkiss, K., G. Luke, and J. Behnam, Female chromosomes in cockerel ejaculates. Proc Biol Sci, 1996. 263(1374): p. 1245-9.

Bresler, M., et al., Manipulations of germ-cell populations in the gonad of the fowl. Br Poult Sci, 1994. 35(2): p. 241-7.

Vick, L., G. Luke, and K. Simkiss, Germ-line chimaeras can produce both strains of fowl with high efficiency after partial sterilization. J Reprod Fertil, 1993. 98(2): p. 637-41.

Simkiss, K., et al., The production of transgenic birds from primordial germ cell manipulated embryos, in Avian Endocrinology, P.J. Sharp, Editor. 1993, Society for Endocrinology: [Bristol]. p. 408p.

Page, N., et al., Transfection of chick cells by non-retroviral DNA. Biochem Soc Trans, 1991. 19(3): p. 328S.

biosci-lukegedit

Contact Details

Email:
g.n.luke@reading.ac.uk
Telephone:
+44 (0) 118 378 5092
Fax:
+44 (0) 118 378 0180
Building:
103 Hopkins

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