Staff Profile:Professor Gavin Brooks

Name:

Professor Gavin Brooks

Job Title:

Pro-Vice-Chancellor (Teaching and Learning), Professor of Cardiovascular Research

Responsibilities:

Areas of Interest:

Cardiovascular disease, including heart failure and atherosclerosis, remains the most common cause of death in the Western world. In an effort to understand more clearly the cellular mechanisms that lead to heart failure and vascular disease, our laboratory is focussing on the mechanisms that control growth and proliferation of cardiovascular cells. Three main research areas currently are under investigation:

• Intracellular controls of cardiac myocyte growth
• Intracellular controls of vascular smooth muscle cell (VSMC) proliferation

Research groups / Centres:

Cardiovascular biology

Institute for Cardiovascular & Metabolic Research

Publications:

Y

Jump to: 2011 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987

Number of items: 91.

2011

• Valasek, P., Theis, S., DeLaurier, A., Hinits, Y., Luke, G. N., Otto, A. M., Minchin, J., He, L., Christ, B., Brooks, G., Sang, H., Evans, D. J., Logan, M., Huang, R. and Patel, K. (2011) Cellular and molecular investigations into the development of the pectoral girdle. Developmental Biology, 357 (1). pp. 108-116. ISSN 0012-1606 doi: 10.1016/j.ydbio.2011.06.031
• Moseley, F. L., Faircloth, M. E., Lockwood, W., Marber, M. S., Bicknell, K. A., Valasek, P. and Brooks, G. (2011) Limitations of the MRL mouse as a model for cardiac regeneration. Journal of Pharmacy and Pharmacology, 63 (5). pp. 648-656. ISSN 2042-7148 doi: 10.1111/j.2042-7158.2011.01261.x

2009

• Aravindan, L. , Bicknell, K. A., Brooks, G., Khutoryanskiy, V. V. and Williams, A. C. (2009) Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine. International Journal of Pharmaceutics, 378 (1-2). pp. 201-210. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2009.05.052
• Mulgrew, C.J., A., C.-S., McLatchie, L.M., Brooks, G., Shattock, M.J. and Hendry, B.M. (2009) Inhibition of human mesangial cell proliferation by targeting T-Type calcium channels. Nephron Experimantal Nephrology, 113 (2). e77-e88. ISSN 1660-2129 doi: 10.1159/000232590
• Coxon, C. H., Bicknell, K. A., Moseley, F. L. and Brooks, G. (2009) Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. PLoS ONE, 4 (8). e6752. ISSN 1932-6203 doi: 10.1371/journal.pone.0006752

2008

• Bicknell, K. A. and Brooks, G. (2008) Reprogramming the cell cycle machinery to treat cardiovascular disease. Current Opinion in Pharmacology, 8 (2). pp. 193-201. ISSN 1471-4892 doi: 10.1016/j.coph.2007.12.015
• Emmott, E., Dove, B. K., Howell, G., Chappell, L. A., Reed, M. L., Boyne, J. R., You, J. H., Brooks, G., Whitehouse, A. and Hiscox, J. A. (2008) Viral nucleolar localisation signals determine dynamic trafficking within the nucleolus. Virology, 380 (2). pp. 191-202. ISSN 1096-0341 doi: 10.1016/j.virol.2008.05.032

2007

• Bicknell, K.A., Coxon, C.N.H. and Brooks, G. (2007) Can the cardiomyocyte cell cycle be reprogrammed? Journal of Molecular and Cellular Cardiology, 42 (4). pp. 706-721. ISSN 0022-2828 doi: 10.1016/j.yjmcc.2007.01.006
• Harrison, S.M., Dove, B.K., Rothwell, L., Kaiser, P., Tarpey, I., Brooks, G. and Hiscox, J.A. (2007) Characterisation of cyclin D1 down-regulation in coronavirus infected cells. FEBS Letters, 581 (7). pp. 1275-1286. ISSN 0014-5793 doi: 10.1016/j.febslet.2007.02.039
• McKoy, G., Bicknell, K. A., Patel, K., Brooks, G. and , (2007) Developmental expression of myostatin in cardiomyocytes and its effect on foetal and neonatal rat cardiomyocyte proliferation. Cardiovascular Research, 74 (2). pp. 304-312. ISSN 0008-6363 doi: 10.1016/j.cardiores.2007.02.023
• Li, J.M., Fan, L.M., George, V.T. and Brooks, G. (2007) Nox2 regulates endothelial cell cycle arrest and apoptosis via p21 (cip1) and p53. Free Radical Biology and Medicine, 43 (6). pp. 976-986. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2007.06.001
• George, V.T., Brooks, G. and Humphrey, T.C. (2007) Regulation of cell cycle and stress responses to hydrostatic pressure in fission yeast. Molecular Biology of the Cel, 18 (10). pp. 4168-4179. ISSN 1059-1524 doi: 10.1091/mbc.E06-12-1141
• Moseley, F.L., Bicknell, K.A., Marber, M.S. and Brooks, G. (2007) The use of proteomics to identify novel therapeutic targets for the treatment of disease. Journal of Pharmacy and Pharmacology, 59 (5). pp. 609-628. ISSN 0022-3573 doi: 10.1211/jpp.59.5.0001

2006

• Dove, B., Brooks, G., Bicknell, K. A., Wurm, T. and Hiscox, J. A. (2006) Cell cycle perturbations induced by infection with the coronavirus infectious bronchitis virus and their effect on virus replication. Journal of Virology, 80 (8). pp. 4147-4156. ISSN 0022-538X doi: 10.1128/jvi.80.8.4147-4156.2006
• Dove, B.K., You, J.H., Reed, M.L., Emmett, S.R., Brooks, G. and Hiscox, J.A. (2006) Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus. Cellular Microbiology, 8 (7). pp. 1147-1157. ISSN 1462-5814 doi: 10.1111/j.1462-5822.2006.00698.x
• Movassagh, M., Bicknell, K. A. and Brooks, G. (2006) Characterisation and regulation of E2F-6 and E2F-6b in the rat heart: a potential target for myocardial regeneration? Journal of Pharmacy and Pharmacology, 58 (1). pp. 73-82. ISSN 0022-3573 doi: 10.1211/jpp.58.1.0009
• Reed, M.L., Dove, B.K., Jackson, R.M., Collins, R., Brooks, G. and Hiscox, J.A. (2006) Delineation and modelling of a nucleolar retention signal in the coronavirus nucleocapsid protein. Traffic, 7 (7). pp. 833-848. ISSN 1398-9219 doi: 10.1111/j.1600-0854.2006.00424.x
• Dove, B.K., Bicknell, K., Brooks, G., Harrison, S. and Hiscox, J.A. (2006) Infectious bronchitis coronavirus induces cell-cycle perturbations. In: Perlman, S. and Holmes, K.V. (eds.) Nidoviruses: toward control of SARS and other nidovirus diseases. Advances in Experimental Medicine and Biology, 581. Springer-Verlag, Berlin, pp. 357-362. ISBN 9780387262024
• Morissette, M.R., Cook, S.A., Foo, S., McKoy, G., Ashida, N., Novikov, M., Scherrer-Crosbie, M., Li, L., Matsui, T., Brooks, G. and Rosenzweig, A. (2006) Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circulation Research, 99 (1). pp. 15-24. ISSN 0009-7330 doi: 10.1161/01.RES.0000231290.45676.d4
• Harper, J.V. and Brooks, G. (2006) The eukaryotic cell cycle. In: Hiscox, J.A. (ed.) Viruses and the nucleus. Wiley, Chichester, pp. 25-68. ISBN 9780470851128

2005

• Humphrey, T. and Brooks, G., eds. (2005) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp402. ISBN 9781588291448
• Brooks, G. (2005) Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 291-298. ISBN 9781588291448 doi: 10.1385/1-59259-857-9:291
• Bicknell, K., Brooks, G., Kaiser, P., Chen, H. Y., Dove, B. K. and Hiscox, J. A. (2005) Nucleolin is regulated both at the level of transcription and translation. Biochemical and Biophysical Research Communications, 332 (3). pp. 817-822. ISSN 0006-291X doi: 10.1016/j.bbrc.2005.05.022
• Harper, J.V. and Brooks, G. (2005) The mammalian cell cycle: an overview. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 113-153. ISBN 9781588291448 doi: 10.1385/1-59259-857-9:113

2004

• Brooks, G. (2004) Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. Methods in Molecular Biology, 296. pp. 291-8. ISSN 1064-3745 doi: 10.1385/1592598579
• Bicknell, K. A., Coxon, C. H. and Brooks, G. (2004) Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes. The Biochemical Journal, 382 (2). pp. 411-6. ISSN 1470-8728
• Harper, J. V. and Brooks, G. (2004) The Mammalian cell cycle: an overview. Methods in Molecular Biology, 296. pp. 113-54. ISSN 1064-3745
• Gray, L. S., Perez-Reyes, E., Gamorra, J. C., Haverstick, D. M., Shattock, M., McLatchie, L., Harper, J., Brooks, G., Heady, T. and Macdonald, T. L. (2004) The role of voltage gated T-type Ca2+ channel isoforms in mediating "capacitative" Ca2+ entry in cancer cells. Cell Calcium, 36 (6). pp. 489-97. ISSN 0143-4160 doi: 10.1016/j.ceca.2004.05.001

2003

• Li, J. M., Fan, L. M., Shah, A. and Brooks, G. (2003) Targeting αvβ3 and α5β1 for gene delivery to proliferating VSMCs: synergistic effect of TGF-β1. American Journal of Physiology-Heart and Circulatory Physiology, 285 (3). H1123-H1131. ISSN 0363-6135
• Vara, D., Bicknell, K. A., Coxon, C. H. and Brooks, G. (2003) Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy. The Journal of Biological Chemistry, 278 (24). pp. 21388-21394. ISSN 1083-351X doi: 10.1074/jbc.M212612200
• Wang, Y. Q., Brooks, G., Harper, J., Li, Y. Q., Zhu, C. B., Yuan, W. Z. and Wu, X. S. (2003) Inhibition of vascular smooth muscle cell proliferation by non-steroidal anti-inflammatory drugs. Shi Yan Sheng Wu Xue Bao, 36 (2). pp. 85-90. ISSN 0001-5334
• Brooks, G., Yu, X. M., Wang, Y. Q., Crabbe, M. J. C., Shattock, M. J. and Harper, J. V. (2003) Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle. Journal of Pharmacy and Pharmacology, 55 (4). pp. 519-526. ISSN 0022-3573 doi: 10.1211/002235702775
• Mulgrew, C. J., Shattock, M. J., Brooks, G. and Hendry, B. M. (2003) Targeting T-type calcium channels in human mesangial cell proliferation. Journal of the American Society of Nephrology, 14. 342A-342A. ISSN 1046-6673
• Bicknell, K. A., Surry, E. L. and Brooks, G. (2003) Targeting the cell cycle machinery for the treatment of cardiovascular disease. Journal of Pharmacy and Pharmacology, 55 (5). pp. 571-591. ISSN 2042-7158 doi: 10.1211/002235703765344487

2002

• Brooks, G. (2002) Gene therapy. The use of DNA as a drug. The Pharmaceutical Press, pp328. ISBN 0853694559
• VARA, D.J., MOVASSAGH, M. and Brooks, G. (2002) Gene therapy for the treatment of cardiovascular diseases. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 135-188.
• Chen, H., Wurm, T., Britton, P., Brooks, G. and Hiscox, J.A. (2002) Interaction of the coronavirus nucleoprotein with nucleolar antigens and the host cell. Journal of Virology, 76 (10). pp. 5233-5250. ISSN 0022-538X doi: 10.1128/JVI.76.10.5233-5250.2002
• Bicknell, K. A. and Brooks, G. (2002) Methods for delivering DNA to target tissues and cells. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 23-49. ISBN 9780853694557
• Brooks, G. (2002) An introduction to DNA and its use in gene therapy. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 1-21. ISBN 9780853694557
• Mahadeva, H., Brooks, G., Chong, N.W., Lodwick, D. and Samani, N.J. (2002) ms1, a novel stress-responsive, muscle-specific gene that is up-regulated in the early stages of pressure overload-induced left ventricular hypertrophy. FEBS Letters, 521 (1-3). pp. 100-104. ISSN 0014-5793

2001

• Wurm, T., Chen, H., Hodgson, T., Britton, P., Brooks, G. and Hiscox, J.A. (2001) Localization to the nucleolus is a common feature of coronavirus nucleoproteins and the protein may disrupt host cell division. Journal of Virology, 75 (19). pp. 9345-9356. ISSN 0022-538X doi: 10.1128/JVI.75.19.9345-9356.2001
• Hiscox, J.A., Wurm, T., Wilson, L., Britton, P., Cavanagh, D. and Brooks, G. (2001) The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus. Journal of Virology, 75 (1). pp. 506-512. ISSN 0022-538X doi: 10.1128/JVI.75.1.506-512.2001

1999

• Poolman, R.A., Li, J.-M., Durand, B. and Brooks, G. (1999) Altered expression of cell cycle proteins and prolonged duration of cardiac myocyte hyperplasia in p27KIP1 knockout mice. Circulation Research, 85 (2). pp. 117-127. ISSN 0009-7330
• Li, J.-M. and Brooks, G. (1999) Cell regulatory molecules and the cardiovascular system: Potential targets for therapy. European Heart Journal, 20 (6). pp. 406-420. ISSN 0195-668X doi: 10.1053/euhj.1998.1308
• Brooks, G. and La Thangue, N.B. (1999) The cell cycle and drug discovery: The promise and the hope. Drug Discovery Today, 4 (10). pp. 455-463. ISSN 1359-6446 doi: 10.1016/S1359-6446(99)01400-2

1998

• Poolman, R.A., Gilchrist, R. and Brooks, G. (1998) Cell cycle profiles and expression of p21CIP1 and P27KIP1 during myocyte development. International Journal of Cardiology, 67 (1). pp. 133-142. ISSN 0167-5273 doi: 10.1016/S0167-5273(98)00320-9
• Brooks, G. (1998) Biotechnology in healthcare: an introduction to biopharmaceuticals. The Pharmaceutical Press, pp228. ISBN 0853693722
• Atsumi, T., Khamashta, M.A., Haworth, R.S., Brooks, G., Amengual, O., Ichiawa, K., Koike, T. and Hughes, G.R.V. (1998) Arterial disease and thrombosis in the antiphospholipid syndrome (APS): A pathogenic role for endothelin-1 (ET-1). Arthritis and Rheumatism, 41 (5). pp. 800-807. ISSN 0004-3591 doi: 10.1002/1529-0131(199805)41:5<800::AID-ART5>3.0.CO;2-J
• Brooks, G., Poolman, R.A. and Li, J.-M. (1998) Arresting developments in the cardiac myocyte cell cycle: Role of cyclin-dependent kinase inhibitors. Cardiovascular Research, 39 (2). pp. 301-311. ISSN 0008-6363 doi: 10.1016/S0008-6363(98)00125-4
• Galinanes, M., Goss, M.W., McGill, C.J., Hearse, D.J. and Brooks, G. (1998) Diacylglycerol-induced protection against injury during ischemia and reperfusion can be achieved without activation of protein kinase C in the rat heart: Comparative studies with ischemic preconditioning. International Journal of Cardiology, 65 (2). pp. 129-138. ISSN 0167-5273 doi: 10.1016/S0167-5273(98)00108-9
• Haworth, R.S., Brooks, G., Cummins, P., Dobie, K., Chilton, D.C. and Avkiran, M. (1998) Differential changes in transforming growth factor β isoform expression during postnatal cardiac growth. Biochemical and biophysical research communications, 245 (3). pp. 923-927. ISSN 0006-291X doi: 10.1006/bbrc.1998.8528
• Poolman, R.A. and Brooks, G. (1998) Expressions and activities of cell cycle regulatory molecules during the transition from myocyte hyperplasia to hypertrophy. Journal of Molecular and Cellular Cardiology, 30 (10). pp. 2121-2135. ISSN 0022-2828 doi: 10.1006/jmcc.1998.0808
• Brooks, G. and Vile, R. (1998) Gene therapy for the treatment of disease. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 83-116. ISBN 9780853693727
• Li, J.-M., Poolman, R.A. and Brooks, G. (1998) Role of G1 phase cyclins and cyclin dependent kinases during hypertrophic growth of adult rat cardiomyocytes. American Journal of Physiology-Heart and Circulatory Physiology, 275 (3 Part 2). H814-H822. ISSN 0363-6135
• Brooks, G. (1998) Transgenic animals as a source of biopharmaceuticals. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 131-146. ISBN 9780853693727
• Brooks, G. (1998) An introduction to basic molecular biology. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 1-15. ISBN 9780853693727
• Brooks, G. (1998) The polymerase chain reaction (PCR): General applications and potential for clinical use. In: Brooks, G. (ed.) Biotechnology in Healthcare: An Introduction to Biopharmaceuticals. The Pharmaceutical Press, UK, pp. 61-81. ISBN 9780853693727

1997

• Li, J.-M. and Brooks, G. (1997) Differential protein expression and subcellular distribution of TGFβ1, β2 and β3 in cardiomyocytes during pressure overload-induced hypertrophy. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2213-2224. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0457
• Brooks, G., Poolman, R.A., McGill, C.J. and Li, J.-M. (1997) Expression and activities of cyclins and cyclin-dependent kinases in developing rat ventricular myocytes. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2261-2271. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0471
• Brooks, G., Goss, M.W., Rozengurt, E. and Galinanes, M. (1997) Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2273-2284. ISSN 0022-2828 doi: 10.1006/jmcc.1997.0466
• Poolman, R.A. and Brooks, G. (1997) Braking the cardiac myocyte cell cycle: Role of cyclin-dependent kinase inhibitors. British Society for Cardiovascular Research Bulletin, 10 (1). pp. 4-10.
• Haworth, R.S., Yasutake, M., Brooks, G. and Avkiran, M. (1997) Cardiac Na+/H+ exchanger during post-natal development in the rat: Changes in mRNA expression and sarcolemmal activity. Journal of Molecular and Cellular Cardiology, 29 (1). pp. 321-332. ISSN 0022-2828 doi: 10.1006/jmcc.1996.0277
• Li, J.-M. and Brooks, G. (1997) Downregulation of cyclin-dependent kinase inhibitors p21 and p27 in pressure-overload hypertrophy. American Journal of Physiology-Heart and Circulatory Physiology, 273 (2). H1358-H1367. ISSN 0363-6135
• McGill, C.J. and Brooks, G. (1997) Expression and regulation of 80K/MARCKS, a major substrate of protein kinase C, in the developing rat heart. Cardiovascular Research, 34. pp. 368-376. ISSN 0008-6363 doi: 10.1016/S0008-6363(97)00041-2

1996

• Brooks, G., Brooks, S.F. and Goss, M.W. (1996) MARCKS functions as a novel growth/tumour suppressor in cells of melanocyte origin. Carcinogenesis, 17 (4). pp. 683-689. ISSN 0143-3334 doi: 10.1093/carcin/17.4.683
• Brooks, G. and Hearse, D.J. (1996) Role of protein kinase C in ischemic preconditioning: Player or spectator? Circulation Research, 79 (3). pp. 628-631. ISSN 0009-7330

1995

• McGill, C.J. and Brooks, G. (1995) Cell cycle control mechanisms and their role in cardiac growth. Cardiovascular Research, 30 (4). pp. 557-569. ISSN 0008-6363
• Brooks, G. (1995) The use of transgenic animals in medicine, surgery and pharmaceuticals. BioAccess, 1 (3). pp. 10-13.

1994

• Brooks, G. (1994) Gene therapy. Pharmaceutical Journal, 252. pp. 256-260. ISSN 0031-6873
• Brooks, G. (1994) Transgenic animals. Pharmaceutical Journal, 253 (6802). pp. 227-231. ISSN 0031-6873
• Goss, M.W. and Brooks, G. (1994) The polymerase chain reaction. Pharmaceutical Journal, 253. pp. 884-889. ISSN 0031-6873
• Brooks, G. (1994) The role of 80K/MARCKS, a specific substrate of protein kinase C, in cell growth and tumour progression. Pigment Cell Research, 7 (6). pp. 451-457. ISSN 0893-5785 doi: 10.1111/j.1600-0749.1994.tb00074.x

1993

• Brooks, G., Goss, M.W., East, J.A. and Hart, I.R. (1993) Growth of melanocytic cells is associated with down-regulation of protein kinase C α,δ and ε isoforms: Possible role of diacylglycerol. The Journal of Biological Chemistry, 268. pp. 23868-23875. ISSN 1083-351X

1992

• Brooks, G., Goss, M.W. and Hart, I.R. (1992) Differential induction of 12-O-tetradecanoylphorbol 13-acetate sequence gene expression in murine melanocytes and melanoma cells. Molecular Carcinogenesis, 5 (4). pp. 328-333. ISSN 0899-1987 doi: 10.1002/mc.2940050414
• Brooks, G. and Hart, I.R. (1992) Signal transduction mechanisms involved in melanocytic cell growth and progression. In: Spandidos, D.A. (ed.) Current Perspectives on Molecular and Cellular Oncology. JAI Press Ltd, London, pp. 175-209.

1991

• Brooks, G., Wilson, R.E., Dooley, T.P., Goss, M.W. and Hart, I.R. (1991) Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth. Cancer Research, 51. pp. 3281-3288. ISSN 0008-5472

1990

• Evans, A.T., Brooks, G. and Evans, F.J. (1990) Non-promoting diterpene esters can induce Epstein-Barr Virus early antigen expression in the Raji cell line. Cancer Letters, 49 (1). pp. 25-29. ISSN 0304-3835 doi: 10.1016/0304-3835(90)90135-K
• Brooks, G. and Brooks, S.F. (1990) Both tumour-promoting and non-promoting phorbol esters inhibit 125I-EGF binding and stimulate the phosphorylation of a 80kd protein kinase C substrate protein in intact Swiss 3T3 cells. Carcinogenesis, 11 (4). pp. 667-672. ISSN 0143-3334 doi: 10.1093/carcin/11.4.667
• Brooks, G., Evans, A.T., Aitken, A., Evans, F.J., Rizk, A.-F., Hammouda, F.M., El-Missery, M.M. and Ismail, S.E. (1990) Daphnane diterpenes of Thymelaea hirsuta. Phytochemistry, 29 (7). pp. 2235-2237. ISSN 0031-9422 doi: 10.1016/0031-9422(90)83044-2
• Brooks, G. (1990) Drug-induced photosensitivity. Pharmaceutical Journal, 245. pp. 19-21. ISSN 0031-6873
• Brooks, G., Birch, M. and Hart, I.R. (1990) Effects of biologically active tumour-promoting and non-promoting phorbol esters on in vivo growth of melanocytic cells. Pigment Cell Research, 3 (2). pp. 98-100. ISSN 0893-5785 doi: 10.1111/j.1600-0749.1990.tb00328.x
• Brooks, G., Goss, M.W. and Hart, I.R. (1990) Inhibition of 125I-epidermal growth factor binding to murine fibroblasts and keratinocytes by irradiation with ultraviolet-B light. Carcinogenesis, 11 (7). pp. 1223-1227. ISSN 0143-3334 doi: 10.1093/carcin/11.7.1223
• Brooks, G. and Evans, F.J. (1990) Toxic hazards of plants from the families Euphorbiaceae and Thymelaeaceae. In: Rizk, A.-F. (ed.) Poisonous Plant Contamination of Edible Plants. CRC Press, Boca Raton, USA, pp. 27-63. ISBN 9780849363696
• Brooks, G., Evans, A.T., Markby, D.P., Harrison, M.E., Baldwin, M.A. and Evans, F.J. (1990) An ingenane diterpene from Belizian Mabea excelsa. Phytochemistry, 29 (5). pp. 1615-1617. ISSN 0031-9422 doi: 10.1016/0031-9422(90)80132-Z

1989

• Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1989) Tumour-promoting and hyperplastic effects of phorbol and daphnane esters in CD-1 mouse skin and a synergistic effect of calcium ionophore with a non-promoting activator of protein kinase C. Carcinogenesis, 10 (2). pp. 283-288. ISSN 0143-3334
• Markby, D.P., Brooks, G., Evans, A.T. and Evans, F.J. (1989) The poison sap tree and its pro-inflammatory constituent: a potent activator of protein kinase C. Lancet, 8560. p. 1320. ISSN 0140-6736

1988

• Brooks, G., Morrice, N., Aitken, A. and Evans, F.J. (1988) Partial synthesis of the phorbol ester probe, Sapintoxin D. Phytochemistry, 27 (5). pp. 1523-1524. ISSN 0031-9422

1987

• Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1987) Sapintoxin A, a fluorescent phorbol ester that is a potent activator of protein kinase C but is not a tumour promoter. Cancer Letters, 38. pp. 165-170. ISSN 0304-3835
• Edwards, M.C., Williamson, E.M., Foumokong, E., Brooks, G. and Evans, F.J. (1987) Secretion and properties of a polypeptide factor generated by phorbol ester stimulation of human blood platelets. Biochemical Pharmacology, 36 (14). pp. 2418-2420. ISSN 0006-2952 doi: 10.1016/0006-2952(87)90613-7
• Brooks, G., Evans, A.T., Morrice, N., Ellis, C., Aitken, A. and Evans, F.J. (1987) Toxic phorbol esters from Chinese Tallow (Sapium sebiferum L.Roxb.). Toxicon, 25 (11). pp. 1229-1233. ISSN 0041-0101 doi: 10.1016/0041-0101(87)90141-3
• Ellis, C.A., Brooks, S.F., Brooks, G., Evans, A.T., Morrice, N., Evans, F.J. and Aitken, A. (1987) The effects of phorbol esters with different activities on protein kinase C. Phytotherapy Research, 1 (4). 187 -192. ISSN 0951-418X doi: 10.1002/ptr.2650010412

This list was generated on Sat May 25 06:27:14 2013 BST.