The cumulative observed model quality of the top ranked models produced by each method. The McGuffin group methods are indicated in bold. The ModFOLD servers did not participate in the TS category, however the cumulative scores for the top ranked models are are shown for comparison with server methods. The McGuffin results are from our manual TS predictions, which were made using a beta version of the ModFOLD v 2.0 method to select models. Methods are ranked by the combined score, which is the mean of the TM-score, MaxSub and GDT-TS scores.
Method TMscore MaxSub GDT Combined
ModFOLDclust 87.642 74.452 78.643 80.246
Zhang-Server 87.455 74.170 78.211 79.946
ModFOLDv2_0 86.992 73.974 78.070 79.679
pro-sp3-TASSER 85.360 71.514 75.737 77.537
RAPTOR 84.572 71.714 75.785 77.357
METATASSER 84.793 71.328 74.854 76.992
Phyre_de_novo 83.633 70.266 74.931 76.277
MULTICOM-REFINE 83.725 70.218 74.774 76.239
MULTICOM-CLUSTER 83.516 70.257 74.596 76.123
HHpred5 83.519 70.154 74.404 76.026
MUProt 83.315 69.868 74.360 75.848
BAKER-ROBETTA 83.463 69.587 74.276 75.775
HHpred2 83.406 69.529 74.006 75.647
HHpred4 83.297 69.510 73.917 75.575
FAMSD 83.042 69.131 73.642 75.272
MUSTER 82.978 68.818 73.389 75.061
MULTICOM-RANK 82.297 68.866 73.497 74.887
GS-KudlatyPred 82.126 69.150 73.344 74.873
SAM-T08-server 82.148 68.410 72.821 74.460
Pcons_multi 82.084 68.417 72.812 74.438
MULTICOM-CMFR 81.963 68.298 72.922 74.394
COMA-M 81.575 67.876 72.633 74.028
PS2-server 81.264 68.003 72.540 73.935
3DShot2 81.639 67.683 71.353 73.558
FFASsuboptimal 80.252 67.298 71.584 73.045
Phyre2 80.623 66.395 70.978 72.666
FEIG 80.349 66.213 70.327 72.297
PSI 80.321 65.855 70.579 72.252
COMA 79.838 65.811 70.329 71.993
FFASstandard 79.010 66.381 70.429 71.940
Phragment 79.515 65.230 70.092 71.612
FFASflextemplate 78.635 65.692 69.934 71.420
nFOLD3 78.528 65.580 69.608 71.238
mGenTHREADER 78.104 65.383 69.727 71.071
Poing 78.976 64.431 69.422 70.943
Pcons_dot_net 78.037 65.201 69.423 70.887
ModFOLDv1_1 77.832 64.956 69.260 70.683
circle 78.315 64.428 68.959 70.567
3D-JIGSAW_V3 77.871 64.148 69.184 70.401
CpHModels 77.369 64.975 68.816 70.387
3D-JIGSAW_AEP 77.363 64.370 68.762 70.165
BioSerf 77.688 63.839 68.818 70.115
GeneSilicoMetaServer 77.106 64.239 68.448 69.931
FALCON 77.624 63.041 68.152 69.606
fais-server 77.260 63.405 67.752 69.472
SAM-T06-server 77.183 62.389 67.814 69.129
GS-MetaServer2 75.846 63.625 67.509 68.993
Pcons_local 75.266 62.819 66.841 68.309
SAM-T02-server 74.271 62.665 66.474 67.803
pipe_int 74.518 61.687 66.089 67.431
keasar-server 73.183 61.003 65.590 66.592
3Dpro 72.425 59.349 63.794 65.189
FALCON_CONSENSUS 72.768 57.384 62.859 64.337
FUGUE_KM 71.357 58.330 63.206 64.298
forecast 69.451 55.693 60.748 61.964
ACOMPMOD 68.651 54.978 59.910 61.180
Frankenstein 66.984 55.523 59.782 60.763
panther_server 67.759 55.202 58.833 60.598
MUFOLD-Server 68.222 51.807 58.334 59.454
Pushchino 64.020 53.980 57.590 58.530
Distill 66.119 50.554 55.015 57.229
rehtnap 63.127 51.181 54.941 56.417
LEE-SERVER 60.806 52.362 54.633 55.934
LOOPP_Server 62.029 49.660 54.495 55.395
Fiser-M4T 56.117 48.827 50.743 51.896
FOLDpro 54.966 39.860 46.104 46.977
YASARA 48.543 42.384 44.357 45.094
mariner1 47.146 33.167 39.015 39.776
OLGAFS 40.905 31.517 35.950 36.124
huber-torda-server 39.163 32.279 35.262 35.568
MUFOLD-MD 39.293 26.787 32.879 32.986
RBO-Proteus 35.244 23.622 29.343 29.403
schenk-torda-server 18.788 9.662 14.169 14.206
mahmood-torda-server 11.305 6.704 9.932 9.314
Jiang_Zhu 3.611 3.009 3.266 3.295
BHAGEERATH 1.374 1.204 1.549 1.376
DistillSN 1.286 0.479 0.850 0.871
SHORTLE 0.863 0.843 0.848 0.851
LEE 0.849 0.769 0.799 0.805
xianmingpan 0.751 0.704 0.694 0.716
test_http_server_01 0.787 0.625 0.686 0.699
HCA 0.413 0.246 0.351 0.337